Gene Information

Name : Thicy_0805 (Thicy_0805)
Accession : YP_004537056.1
Strain : Thioalkalimicrobium cyclicum ALM1
Genome accession: NC_015581
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 953109 - 954542 bp
Length : 1434 bp
Strand : -
Note : TIGRFAM: DNA helicase, DnaB type; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; KEGG: tcx:Tcr_1360 replicative DNA helicase; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGACCAAAACACCCGCTAACGAAATCTTTAAAATCCCACCACACTCTGAAGAAGCTGAGCAATCAGTTCTTGGTGCTTT
AATGCTCTCCGGTGATATTTTCGATGAGGTTTTTGGTTTAATTAATGAACAAGATTTTTATACTAAACAACATCAGCGTA
TTTTTTCAGCGATCCATACCTTAGCTCAGCGAAGTACAGCGGTGGATTTAGTCACGCTTACCAGTCATTTAGAAGCACAG
AACCAATTAACTGATTGCGGTGGACGGCATTATTTAATTGATTTAGTAACCAACACACCAGGTCCAAGTAACGCATTATT
TTATGCTCGAATTGTTAGAGAGAAGGCGATCCTTCGTCAATTAATAGCGGCTTCAAATGACATTGCTAATCGTTGTTATA
ACAGCAAAGGCGCAACCACCCGTGATATCCTTGACCAGGCAGAGTCTAGCGTTTTGGCTATTGCAGAGCATGGTGCCGGA
AAACAGCGTCAATATATGACAATTGATGATTTGCTTGGTAGCGCCATGATTCGCTTAGATGAGATTTTTAATACCGAAGG
GAATATTACCGGTATCGCCACACATTTATCCGCCTTTGACGATATGACCGCAGGCTTGCAGCGGGGTGATTTATTAATTG
TTGCTGGACGCCCCTCAATGGGGAAAACCACCTTCTCGATGAATGTCGCTGAAAATGTCGCTACGCGCTCAAAAGAACCT
GTTGCGGTGTTTAGTTTAGAAATGCCAGGAGAACAGTTAGCTCTAAGGATGCTAAGTTCGATTGGTCGCATTGATTCAAA
AAAAATGCGGACCGGTGACTTAGGTCCTGAAGATTGGAGTAACCTGAATGCGGCTGTAGCAAAGTTATCATCAGCACAAA
TTTTCATTGATGATACGCCGGCACTATCAATCAATGAGTTACGTGCACGAGCAAGGCGTATCGACAAGGATGTGCGTGAA
AAACAACGTCGTGAAGCGATTGCAGAAGGGGTAGATTTAGATGCTATTAACGCAAAAGGACTAGGATTAATAGTTATTGA
CTACTTACAATTAATGCGCGGCTCAACACAAACTGATAACCGTGTTAACGAAATTTCTGAGATTTCACGCGGTTTAAAAG
CATTAGCGAAAGAATTAAATATTCCTGTTATCGCTTTGTCGCAGTTAAATCGTAGCCTTGAACAACGCCCTAACAAACGC
CCGGTAATGTCGGATTTACGAGAGTCAGGTGCTATTGAGCAAGATGCCGATTTAATCATCTTTATTTATCGCGATGAGGT
TTATAATCCTGATAGTGAAGATAAAGGCACCGCCGAAATTATTATTGGTAAGCATCGTAACGGTTCTATTGGAACGCTAA
GACTGACCTTTATTGGTCAATATACTCGCTTTGAAAACTTCATTAACCTTCCTGATCAAGATAATCATTTTTAA

Protein sequence :
MTKTPANEIFKIPPHSEEAEQSVLGALMLSGDIFDEVFGLINEQDFYTKQHQRIFSAIHTLAQRSTAVDLVTLTSHLEAQ
NQLTDCGGRHYLIDLVTNTPGPSNALFYARIVREKAILRQLIAASNDIANRCYNSKGATTRDILDQAESSVLAIAEHGAG
KQRQYMTIDDLLGSAMIRLDEIFNTEGNITGIATHLSAFDDMTAGLQRGDLLIVAGRPSMGKTTFSMNVAENVATRSKEP
VAVFSLEMPGEQLALRMLSSIGRIDSKKMRTGDLGPEDWSNLNAAVAKLSSAQIFIDDTPALSINELRARARRIDKDVRE
KQRREAIAEGVDLDAINAKGLGLIVIDYLQLMRGSTQTDNRVNEISEISRGLKALAKELNIPVIALSQLNRSLEQRPNKR
PVMSDLRESGAIEQDADLIIFIYRDEVYNPDSEDKGTAEIIIGKHRNGSIGTLRLTFIGQYTRFENFINLPDQDNHF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 5e-80 43
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 2e-85 43
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 1e-79 43
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 3e-80 42
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 6e-73 41
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 2e-79 41