Gene Information

Name : Thicy_0455 (Thicy_0455)
Accession : YP_004536707.1
Strain : Thioalkalimicrobium cyclicum ALM1
Genome accession: NC_015581
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 589855 - 591435 bp
Length : 1581 bp
Strand : +
Note : PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA methyl transferase-like; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; HAMAP: GMP synthase [glutamine-hydrolyzing]; KEGG: tcx:Tcr_1615 GMP synthase

DNA sequence :
ATGACTCAGCACTCAATACATGAACACCGCATTTTAATTTTGGACTTTGGTTCACAATACACCCAACTCATTGCACGACG
CATTCGCGAGATTGGGGTTTATTGTGAAATCGAACCCTGGGATGTTGATGCGCAATTTATTCGGGACTTTGGGGCTAAGG
GCATTATTCTCTCGGGCGGACCAGAAACGGTTATCGGAGACGATGCGCCAAAAGCACCAGGCCTGGTATTTGAGCTTGGT
GTGCCGTTATTGGGTATTTGTTACGGTATGCAAACCATGGCTCAACAGTTGGGTGGTCAAGTGATTCATGCCAATGAGCA
TGAATATGGCTACGCGCAGGTGCGTGCCCGCGGCCATACCGATTTATTTCGTGATATCGAAGATCATGTTAATGTCGAAG
GGCATGGATTATTAGATGTTTGGATGTCGCATGGTGATCGTGTCGACCAGGTGCCTAATGGCTTTAAATTGATGGCAAGC
ACGGAAAGCTGCCCAATTGCTGGTATGGCCGATGAAACTAGGCGGTTTTACGGTATTCAGTTTCATCCCGAAGTAACCCA
TACCAAACAGGGCTTGCGTATTTTAGAACGTTTCGTATCGCAGATTTGTGGTTGTGAAAAGCTTTGGACAACGGCGAATA
TTGTTGAAGACTCGATTGCCCGCGTTCGCGAGCAGGTTGGTGGCGATGACGTATTGCTTGGTTTGTCTGGCGGTGTCGAT
TCGTCGGTGGTTGCGGCCTTGTTGCACAAAGCTATTGGTGACCAGTTAACCTGTGTGTTTGTTGATCATGGTCTATTACG
TCATCAAGAAGGTGATCAGGTTATGGCGATGTTTGCGCAAAATATGGGCGTAAAGGTCATTCGTGTTGATGCCGAACAAC
GCTTTATGGATAAGCTGGTTGGTGAAGCGGACCCCGAAAAGAAACGCAAAATTATTGGTCATACCTTTATTGAGGTGTTT
GATGAGGAATCCTCAAAGCTGACGAATGTGAAGTGGTTAGCGCAAGGTACAATTTATCCGGATGTTATTGAGTCGGCTGG
TTCTAAAACTGGCAAGGCCAAAGTCATTAAGTCGCATCATAATGTCGGTGGCTTACCAGAGGATATGGAGCTTAAATTGC
TTGAGCCTTTGCGTGAGTTATTTAAAGATGAAGTTCGCAAGCTTGGTGTTGAGTTGGGTCTGCCGGCCGATATGGTGTAT
CGCCATCCTTTCCCGGGACCAGGCCTGGGAGTACGAATTTTGGGCGAAGTTAAAAAAGAATATGCCGATATTTTGCGTTT
AGCGGACCATATTTTTATCGAAGAATTGCGCAAAGCAGATTTGTACGATGAAACCTCTCAAGCCTTCACGGTGTTTTTAC
CGGTCAAGTCTGTTGGGGTGGTCGGCGATGCACGTCGTTATGATTATGTGGTGAGTTTACGTGCGGTCGAAACCATTGAT
TTCATGACCGCACGTTGGGCGCATCTACCCTATGAGTTTTTAGAAAAAGTGTCGAATCGGATTATCAATGAAATCCCACG
AATCTCTCGCGTCACCTATGATATTTCGAGTAAACCACCCGCGACGATTGAATGGGAATAA

Protein sequence :
MTQHSIHEHRILILDFGSQYTQLIARRIREIGVYCEIEPWDVDAQFIRDFGAKGIILSGGPETVIGDDAPKAPGLVFELG
VPLLGICYGMQTMAQQLGGQVIHANEHEYGYAQVRARGHTDLFRDIEDHVNVEGHGLLDVWMSHGDRVDQVPNGFKLMAS
TESCPIAGMADETRRFYGIQFHPEVTHTKQGLRILERFVSQICGCEKLWTTANIVEDSIARVREQVGGDDVLLGLSGGVD
SSVVAALLHKAIGDQLTCVFVDHGLLRHQEGDQVMAMFAQNMGVKVIRVDAEQRFMDKLVGEADPEKKRKIIGHTFIEVF
DEESSKLTNVKWLAQGTIYPDVIESAGSKTGKAKVIKSHHNVGGLPEDMELKLLEPLRELFKDEVRKLGVELGLPADMVY
RHPFPGPGLGVRILGEVKKEYADILRLADHIFIEELRKADLYDETSQAFTVFLPVKSVGVVGDARRYDYVVSLRAVETID
FMTARWAHLPYEFLEKVSNRIINEIPRISRVTYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-125 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-125 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-125 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-111 49