Gene Information

Name : Thicy_1344 (Thicy_1344)
Accession : YP_004537587.1
Strain : Thioalkalimicrobium cyclicum ALM1
Genome accession: NC_015581
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoylalanine--D-glutamate ligase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 1526507 - 1527853 bp
Length : 1347 bp
Strand : -
Note : TIGRFAM: UDP-N-acetylmuramoylalanine-D-glutamate ligase; HAMAP: UDP-N-acetylmuramoylalanine-D-glutamate ligase; KEGG: tcx:Tcr_0566 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Mur ligase, central; Mur ligase, C-terminal

DNA sequence : 
ATGTATCTAGTCATCGGGTTAGGGGTTACAGGACAATCGGTGTTGCGTTATTTAACGCACAATAACGAAACGATATTCGC
CTTTGATACGCGTGAAACCTTGGATATTACCTCTTTGCAGCAAGCCTACCCTGGCGTGCAGTTTGCAACCGGTCAATTGC
CAAAAGCCTGGATTGCTAAAACCGCTATCCTAGTGGTTAGTCCGGGTGTTGATCTGCGCCAGACCTGGTTGCAGGTTTTT
AAGCAAAAGGGCATTGAAATTATTGGCGATATTGAGTTGTTTGCGCGCGCGGCCAGCGCCCCTATCATTGGCATTACTGG
CTCAAATGGCAAAAGTACGGTGACTAGCCTAACAGCTCAATTATTAAGTGCGGCTGGTTATAAAGCCGGGCTGGGCGGTA
ACATTGGAAAACCGGCGTTAGATTTGCTAAAAGAAAACCAAGATTATGATGTGTTTGTGCTCGAGCTATCGAGCTTTCAA
CTAGATACCACCTACTCATTGCACACGGTGGCGGCGACGGTGCTCAATATTTGTGAAGATCACCTTGATCGTTACGATGG
CATGGACGCTTATATTCAATCAAAAAATACCATCTATCAAGATACTGAGTTAGCGGTGATGCCGCTGGAGGAGCCCACTC
ATTTTTGGGTGCCAGGTATTACACCCAGGTACTATTTCGGGCTACAGCACCCTCGCAACAGTAGTGATTGGGGTTTAGTT
ATAGATAAGCAGGGTTTCCGGTATTTGGCCCGGGGTGAACAGTTGATTATGCCCGTGCAAGAGTTAAAACTGCAGGCACC
GCATCAGTTGCTCAATGCTTTGGCTGCGCTTGCCTTGGTTGATGAATTTGCTATTCCGCCGGAAATTATAAGACACGTAC
TAGCTGAGTTTACCGGCCTACCCCATCGTACTGAATGGGTTGCAGAGATGAACGGTGTGACTTGGATTAACGATTCCAAG
GGTACTAACGTTGGAGCGACACTAACCGCTATTAATAGTTTAGGTAGCAATGTAGCGCCTGGCAAGTTGGTGCTGTTGGC
GGGCGGCGATGCTAAGGGGGCAGATATGGCGCCACTAGCCGCTCCCTTGGCGCAATTTGCTCGTGCGGCCATTTTATATG
GCCGAGATGCTGATAAACTCTACCAGGCCTGGTCAGCTGATCTGCCCTGTCATCGATTGGAAACACTGGATGAGGCCGTT
GTTTTGGCAGCTTCATTAGCAAAGGCGGGTGATGCCGTTTTGTTATCACCAGCTTGTGCCAGTCTTGATCAATTTACCAA
TTATCAACATCGTGGCCAGCACTTTATAAGTTGTGTTGCAAACTTGGAGAAATCGTCTCGTGGCTAA

Protein sequence : 
MYLVIGLGVTGQSVLRYLTHNNETIFAFDTRETLDITSLQQAYPGVQFATGQLPKAWIAKTAILVVSPGVDLRQTWLQVF
KQKGIEIIGDIELFARAASAPIIGITGSNGKSTVTSLTAQLLSAAGYKAGLGGNIGKPALDLLKENQDYDVFVLELSSFQ
LDTTYSLHTVAATVLNICEDHLDRYDGMDAYIQSKNTIYQDTELAVMPLEEPTHFWVPGITPRYYFGLQHPRNSSDWGLV
IDKQGFRYLARGEQLIMPVQELKLQAPHQLLNALAALALVDEFAIPPEIIRHVLAEFTGLPHRTEWVAEMNGVTWINDSK
GTNVGATLTAINSLGSNVAPGKLVLLAGGDAKGADMAPLAAPLAQFARAAILYGRDADKLYQAWSADLPCHRLETLDEAV
VLAASLAKAGDAVLLSPACASLDQFTNYQHRGQHFISCVANLEKSSRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 6e-60 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 6e-60 42