Gene Information

Name : TREPR_0218 (TREPR_0218)
Accession : YP_004529133.1
Strain : Treponema primitia ZAS-2
Genome accession: NC_015578
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 64646 - 66319 bp
Length : 1674 bp
Strand : +
Note : identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888

DNA sequence :
ATGGATAAAATACTTATTTTAGATTTTGGCAGCCAGACCACCCAGCTCATCGGACGGCGTATCCGGGACCTGGGGGTCTA
TACAGAGATCATCCCCGGGGACGCGGTTCTCACCGATACTATTCTTGCAGGAAGCGAAGGCAGCGTACTGAGGGGCATCA
TTCTTTCAGGTTCCCCCGAATCGGTCTATACCCAGGAAGGCGCCGTGCCGGACAAAAAGGTCTATACTTCCGGCCTTCCC
CTGCTGGGGATCTGTTACGGCCTTCAGCGCATGACAGCTGATCACGGTGGCCTGGTGGAGCCTTTGCCCAAGCGGGAGTA
TGGCAGGATAGGGGTAACAGTCAGGAATGAGGAAGATACTGCGGGGAAGGGGCTTATTCGGCGCTTTCTTACGGGGTTCG
ATAAGGCTATCCCCCTGGAAAAAATTGTTGAGGGGGCGCCGGGTACTTTGCAAGATCAGCCCTGTACCATTACTGCCTGG
ATGAGCCACGGGGATACCCTTACCCGGCTGGCCCCGGGGTTTCGGGAATACGGCGTCAGTGACACCGGCTACCCCGCAGT
GGCAGCCCACGGAGAAAAACCCTGGTTCGGGCTCCAGTTCCACCCCGAGGTAACCCATACCGAGCGGGGCCTGGAGATAC
TCGCAGCTTTTGTGTTCGGGATTTGTGGTTGCAAAAAAAGCTGGACCATGGAACAGTACGTAGAAGAACTCGGCGATGCC
CTCCGGAAACGGGTGGAAGCAAACCCGGTGTTGCTCCTTATTTCCGGCGGGGTCGATTCCACTGTGGCGGGTGCGCTGCT
CCTCAAAACCCTGAAACCGGACCTGGTCCACCTCATGTATATGGACACCGGCCTCATGCGCAAAGATGAAACAAAAACCG
TTTCTACCGCCCTGGAAAAACTCGGGGCAAAACATCTGCATATTATTCACTGTGAGGAAGAATTTCTCTCTGCCCTGAAA
GGTCTTGAGGACCCGGAGGCGAAACGCAAAGCCATCGGGGATCTGTTCATCACCATCCAGGAGCGTGAGGTGAAGCGGCT
GGGCCTGCCGGATTCCTACTTCCTCGCCCAAGGCACCCTCTACACGGACCTTATTGAAAGTGGCAAGGGGGTAGGCAAAA
AGGCCCATCTGATCAAGAGCCACCACAATGTGGGAAGTCCCCTGGTAGACGCCAAGCGCAAGGCCGGCCGGATCATTGAA
CCCCTGGACCGGCTCTACAAAGACGAAGTCCGCCAACTGGGCCGTATTCTGGGCATAGACGAGGAGGTGGTCCTCCGGCA
CCCCTTCCCCGGGCCTGGCCTGGCGGTGCGTATCCTGGGAGAAGTAACCCAGGAAAAGTGTGACATACTCCGGGAAGCGG
ACGCCATCTATATTGAAGAATTAAAGAGCCGCCTCTCCCCTGAGGGCAAACGGCTCTACGATGAGATATGGCAGGCCTTC
GCGGTACTCCTCCCCATACGCTCCGTAGGCGTGGCTGGGGATGTCCGCAAATACGGCTGGGTCCTCGCTCTGCGGGCCAT
AGTCAGCGCCGACGGCATGACCGCCGATGTGTACCCATTCCAGATAAAAGACCTGCTGGAAATTTCCACCCGCATCACTA
ATACTGTTAAAGACATAGGCCGGGTAAGCTACGATATTTCCTCCAAGCCCCCGGCGACCATTGAATGGGAGTAG

Protein sequence :
MDKILILDFGSQTTQLIGRRIRDLGVYTEIIPGDAVLTDTILAGSEGSVLRGIILSGSPESVYTQEGAVPDKKVYTSGLP
LLGICYGLQRMTADHGGLVEPLPKREYGRIGVTVRNEEDTAGKGLIRRFLTGFDKAIPLEKIVEGAPGTLQDQPCTITAW
MSHGDTLTRLAPGFREYGVSDTGYPAVAAHGEKPWFGLQFHPEVTHTERGLEILAAFVFGICGCKKSWTMEQYVEELGDA
LRKRVEANPVLLLISGGVDSTVAGALLLKTLKPDLVHLMYMDTGLMRKDETKTVSTALEKLGAKHLHIIHCEEEFLSALK
GLEDPEAKRKAIGDLFITIQEREVKRLGLPDSYFLAQGTLYTDLIESGKGVGKKAHLIKSHHNVGSPLVDAKRKAGRIIE
PLDRLYKDEVRQLGRILGIDEEVVLRHPFPGPGLAVRILGEVTQEKCDILREADAIYIEELKSRLSPEGKRLYDEIWQAF
AVLLPIRSVGVAGDVRKYGWVLALRAIVSADGMTADVYPFQIKDLLEISTRITNTVKDIGRVSYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-91 43
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-91 43
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-91 42
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-78 41