Gene Information

Name : TREPR_0345 (TREPR_0345)
Accession : YP_004532535.1
Strain : Treponema primitia ZAS-2
Genome accession: NC_015578
Putative virulence/resistance : Virulence
Product : VI polysaccharide biosynthesis protein VipA/tviB
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : 1.1.1.-
Position : 3998217 - 3999482 bp
Length : 1266 bp
Strand : -
Note : identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026

DNA sequence :
ATGGAAAACATAAAGGTTGCTGTACTTGGCCTTGGTTATGTTGGTCTCCCATTGGCACGGTTGTTTTCAACTAAATATCC
AACAGTTGGTTTTGATATAAATAGTGAACGGGTGAAAGCTTTATTAACAGGCCATGATACAACCTTAGAAATTACAGACG
AATTATTACAATCCGCTTTACGTGATGGGTTTATATGTACCTCCACCATAGATGATATAAGGGAATGTAACTTTTATATT
GTGGCAGTTCCAACGCCTGTCGACAAGAATAATAACCCTGATTTAACGCCGCTTTATAAAGCCAGTGAAGTCGTAGGCGC
AGTTATTTCAAACGGAGATATTGTTGTCTATGAATCGACGGTTTATCCGGGAGTTACAGAAGAAGAATGTATCCCTATCG
TTGAAAGAATTTCGGGATTACGATTTAATCAAGACTTTTTTGCAGGATATTCTCCTGAACGAATAAACCCCGGCGATAAA
TTGCATACGGTTGAAAAAATCAAAAAGATTACATCAGGATCAACTTATGAATCGGGTAAAAAGATAAATGAAGTTTATGC
ATCTGTAATTGAAGCGGGAACCCATTTGGCGCCTTCAATTAAAGTCGCTGAAGCGGCTAAGGTAATAGAAAATGCTCAAC
GGGATATTAATATAGCCTTTGTAAATGAATTATCAAAAATATTTAATTTAATGGAAATAGATACCCATGATGTATTAGAG
GCTGCCGGTACTAAGTGGAATTTTTTATCTTTTAAGCCTGGATTAGTTGGCGGGCATTGTATCGGCGTTGATCCATATTA
TTTAGCGCAGTGTGCGCAAAATTATGGGTACCACCCGGAAATTATTCTTGCAGGACGTAGAACAAATGATGGTATGGGAG
AATATGTCGCCAATCAGGTAATAAAGTTAATGATAAAAAAGCAGTTAAATGTATTAAATTCTAATATTTTAATATTGGGT
TTTACTTTTAAAGAAAATTGCCCTGATGTACGTAATACAAGGGTAATAGATATTTATAATGTCTTTAAAGAATATAATAT
CAATACTACAATATATGAACCATTAGCTGACAAAGCGATAGTTAAACATGAATATAATATTGATATAATAAAAGAATGTC
CCACACAAAAATTTGATGGCGTAGTATTGGCGGTTGGACATAAGATATTTGATACCATTGATGTTTTATCGCTATTAAAA
ACTTCTCATGTTGTTTATGATGCTAAGGCTGTACTGGATAAATCAATAGTTGATGGAAGGCTTTAA

Protein sequence :
MENIKVAVLGLGYVGLPLARLFSTKYPTVGFDINSERVKALLTGHDTTLEITDELLQSALRDGFICTSTIDDIRECNFYI
VAVPTPVDKNNNPDLTPLYKASEVVGAVISNGDIVVYESTVYPGVTEEECIPIVERISGLRFNQDFFAGYSPERINPGDK
LHTVEKIKKITSGSTYESGKKINEVYASVIEAGTHLAPSIKVAEAAKVIENAQRDINIAFVNELSKIFNLMEIDTHDVLE
AAGTKWNFLSFKPGLVGGHCIGVDPYYLAQCAQNYGYHPEIILAGRRTNDGMGEYVANQVIKLMIKKQLNVLNSNILILG
FTFKENCPDVRNTRVIDIYNVFKEYNINTTIYEPLADKAIVKHEYNIDIIKECPTQKFDGVVLAVGHKIFDTIDVLSLLK
TSHVVYDAKAVLDKSIVDGRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-110 58
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-110 58
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-103 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TREPR_0345 YP_004532535.1 VI polysaccharide biosynthesis protein VipA/tviB VFG0431 Protein 2e-110 58