Gene Information

Name : clpB (TREPR_0638)
Accession : YP_004532266.1
Strain : Treponema primitia ZAS-2
Genome accession: NC_015578
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3685111 - 3687729 bp
Length : 2619 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGGATTTCGAAAAATTAACCGTAAAAGCCCAGGAAGCCATTAACGAAGCTTCCGGAATCGCCCAAAAAAACGACCATTC
CCAGATTGAAACCGAACACCTGCTTCTGGCTCTGCTCAGCCAGGAAGATGGCATTGTTTTGCCCATTGTCAAGCAAATCG
GGGCCAATACGGAGCAGCTTATCGCCGACATACAGGCCCTGGTAGCCGCTAGCCCCAAGATTTATGGCGAAGCTGCCCAG
GTATACCTCTCGTCAGCGGCTTCCAAGGTTTTGGCAAAGGCCGAAACCGAGGCCTCTTCCTTAAAAGACGAATACATTTC
CGCCGAACACCTGCTTCTTGCCATAGTCGCCGGGGAAGGGAAGGCTGCGGATGTCCTGAAAAAGGCAGGGGTCACCCATC
AGTCAATCCTTGCCGCATTGAAGCAGGTCCGGGGGAACGCTCGGGTAACTGACCAGAACCCCGAGGGCAAGTACCAGGTT
CTGGACAAGTACTGCCGGGACCTTACCGCCCTGGCCCGGCAGGAAAAGCTCGACCCGGTCATAGGCCGGGACGAGGAAAT
ACGCCGGGTGATGCAGGTCCTGTCCCGGCGCACCAAGAACAACCCGGTCCTCATCGGCGAACCCGGTGTGGGGAAGACCG
CTATCGCCGAAGGCTTGGCCCGGCGCATCGTGGCCGGGGATGTGCCCGAAGGGCTCAAGGGGAAAAAACTCCTGTCCCTG
GATTTAGGCGCCCTGGTAGCGGGGGCCAAGTTTCGGGGGGAATTCGAGGAGCGGCTCAAGGCGGTGATCCACGAGGTCCA
AGCCGCAGACGGGAACATAATACTGTTTATCGACGAACTCCACACCCTGGTGGGCGCGGGGGCCGCAGAAGGCGCCACCG
ACGCCTCCAATCTGCTCAAGCCTGCTCTGGCCCGGGGGGAACTCCGCTGCATAGGCGCCACCACCCTGGACGAGTACCGC
AAACATATTGAAAAAGACGCCGCCCTGGAACGGCGCTTCCAGCAGGTCTACACCGCTGAGCCTTCCGTGGAGGACACGAT
AGCGATACTGCGGGGCTTGCAGGAACGCTACGAGGTACACCACGGGGTGCGTATAAAAGACGAAGCCCTGGTGGCCGCAG
CAACACTGTCGGACCGATACATCACCAGCCGCTTCCTTCCGGATAAGGCCATCGACCTGGTGGACGAAGCGGCCAGCCGT
CTCAAGATGGAACTGGACAGCCGGCCCACGGAGCTGGACAAACTGGAACGGAAACTGTTGCAGCTTTCCATTGAACGGCA
GGCCCTGACCCGCGAAGAGGACGCTGCCTCCAAAGACCGGCTAGGCAAACTGGAAAAAGAAATCGCTGAGCTTACCGCTG
AACGGGATGCTATGAAAGCCCGGTGGGACAGCGAAAAACAGGATATCCAAAAGATAAGGGAAATCAAACAACGCATAGAA
GAACTGCGCATAGAAGAGACCCGTTACGAACGGGAGGGGAACCTCACAAAAGCTGCGGAAGTTAAGCACGGCCGCATCCC
GGAGGCACAGAAAGAGCTTGCCCGGCTCACCGGCTTGATGGAAGAGAAACGGGAAAGCGGCAGAGGCGTGCCGGCCCTGC
TCCGGGAAGAGGTGAGCGAGGAAGATATTGCCCAGGTGGTATCCGCGTGGACTGGCATCCCGGTTTCAAAGATGCTAAGC
GGGGAACTCCAGAAGTACCTGGACTTGGAAAAGGTCCTGGAACAGCGGGTGGTAGGCCAGGGCGCGGCGGTGTCCGCGGT
GGCCGATGCCATCCGGCGGAACAAGGCCGGTCTTTCCGATGCCAGCCGTCCCCTGGGCTCCTTCCTGTTCCTCGGCCCCA
CCGGGGTGGGCAAAACTGAACTTGCAAAGACCCTGGCAGACTTCCTCTTTAACGACGAAAAGGCCCTGACCCGGATCGAC
ATGAGCGAATACGGGGAAAAGCATTCGGTAAGCCGCCTCATCGGTGCGCCTCCGGGCTATGTGGGTTACGAGCAGGGGGG
CCAGCTCACCGAAGCGGTGCGCCGCCGCCCCTACAGCGTGATCCTCTTTGACGAAATCGAGAAGGCCCACCCGGAAGTGT
TCAACGTCTTTCTCCAGATCCTCGACGATGGCCGCCTCACCGACGGCCAGGGCCGGGTGGTGGATTTCAAAAACGTGATC
ATCATCATGACAAGCAACCTTGGCTCAGACCTGATCCTTGGAACCAAAAACCCCGATGACATTAAGGATGGGCTGATGGA
ACTCCTCAAGCAAAGCTTCCGCCCGGAATTCTTAAACCGCATCGATGAGACGGTGATCTTCAACCGCCTGGGCCGGGATG
AGATCAGTAAAATTGTGGACATCCAGCTCAAGCGCCTTTCTGCCCGGCTTCTGGACCGGAAGATCACCCTCACGGTCACC
GATGGTGCCAGGCAGCTTTTGGCGGAACGGGGTTACGATCCCCTCTTCGGCGCCCGGCCCCTAAAACGGACCATACAGGC
GGACCTGGAAAACCCCCTGGCCAAGGGGATCATTGCCGGGAAGATAAAGGACGGGGATGCGGTCACTGCGGACCGAGGTC
CGGCGGACAAAGCGCCCGGTGGAGACGGTCTTATTTTTAAGAAAGGTCCGGCCGTATAG

Protein sequence :
MDFEKLTVKAQEAINEASGIAQKNDHSQIETEHLLLALLSQEDGIVLPIVKQIGANTEQLIADIQALVAASPKIYGEAAQ
VYLSSAASKVLAKAETEASSLKDEYISAEHLLLAIVAGEGKAADVLKKAGVTHQSILAALKQVRGNARVTDQNPEGKYQV
LDKYCRDLTALARQEKLDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIAEGLARRIVAGDVPEGLKGKKLLSL
DLGALVAGAKFRGEFEERLKAVIHEVQAADGNIILFIDELHTLVGAGAAEGATDASNLLKPALARGELRCIGATTLDEYR
KHIEKDAALERRFQQVYTAEPSVEDTIAILRGLQERYEVHHGVRIKDEALVAAATLSDRYITSRFLPDKAIDLVDEAASR
LKMELDSRPTELDKLERKLLQLSIERQALTREEDAASKDRLGKLEKEIAELTAERDAMKARWDSEKQDIQKIREIKQRIE
ELRIEETRYEREGNLTKAAEVKHGRIPEAQKELARLTGLMEEKRESGRGVPALLREEVSEEDIAQVVSAWTGIPVSKMLS
GELQKYLDLEKVLEQRVVGQGAAVSAVADAIRRNKAGLSDASRPLGSFLFLGPTGVGKTELAKTLADFLFNDEKALTRID
MSEYGEKHSVSRLIGAPPGYVGYEQGGQLTEAVRRRPYSVILFDEIEKAHPEVFNVFLQILDDGRLTDGQGRVVDFKNVI
IIMTSNLGSDLILGTKNPDDIKDGLMELLKQSFRPEFLNRIDETVIFNRLGRDEISKIVDIQLKRLSARLLDRKITLTVT
DGARQLLAERGYDPLFGARPLKRTIQADLENPLAKGIIAGKIKDGDAVTADRGPADKAPGGDGLIFKKGPAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-100 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 9e-103 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 7e-103 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_004532266.1 ATP-dependent chaperone ClpB VFG2076 Protein 4e-112 43
clpB YP_004532266.1 ATP-dependent chaperone ClpB VFG2084 Protein 2e-107 42