Gene Information

Name : TREPR_1666 (TREPR_1666)
Accession : YP_004531330.1
Strain : Treponema primitia ZAS-2
Genome accession: NC_015578
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 2599031 - 2599732 bp
Length : 702 bp
Strand : -
Note : identified by match to protein family HMM PF00005

DNA sequence : 
GTGGGATATGTAGAATTTCGGGGGGTATGCAAATACTACACCATGGGGGAAATCAGGATAGCAGCGGCGGATCATCTCAA
TTTTGAGATTGAGAAGGGCGAATTCTGCGTCATCCTGGGACCCAGCGGGGCAGGAAAAACCACCCTCCTCAATATGCTGG
GGGGTATGGATTCCTGTGACGAAGGGGTAATACTCCTGGACGGCCGGGAGATCAGCGCCCTAAACGAGCGGCAGCTCACC
GATTACCGCCGTTACGATGTGGGATTTGTTTTTCAGTTTTACAACCTGATCCAGAACCTTACGGCCCTGGAAAACGTGGA
ACTTGCCTCGGAAATATGTGAGGCAAGCCGGGACCCCGGGGAAACCCTGACGGCGGTGGGCTTGGGGGAACGGATGGGCA
ATTTCCCGGGCCAGCTTTCCGGGGGGGAACAGCAGCGGGTCGCCGTGGCCCGTGCTCTGGCGAAAAACCCCCGGATACTG
CTCTGCGATGAACCCACCGGCGCCCTGGACTATGAGACGGGGAAACACATACTCAGGCTGCTCCAGGATTGTTGCGGGGA
AAACGGGAAGACAGTTATCGTGATCACCCATAACCTGGCCATTGCGGGCATGGCGGACCGGGTGATTGAGCTTAAAAACG
GACAAATTATCAAAATCCACCGGAATGCGAGCCCCCTGCCGGTGGAACAGATTGAGTGGTAA

Protein sequence : 
MGYVEFRGVCKYYTMGEIRIAAADHLNFEIEKGEFCVILGPSGAGKTTLLNMLGGMDSCDEGVILLDGREISALNERQLT
DYRRYDVGFVFQFYNLIQNLTALENVELASEICEASRDPGETLTAVGLGERMGNFPGQLSGGEQQRVAVARALAKNPRIL
LCDEPTGALDYETGKHILRLLQDCCGENGKTVIVITHNLAIAGMADRVIELKNGQIIKIHRNASPLPVEQIEW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-34 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 1e-34 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-34 41
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-32 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TREPR_1666 YP_004531330.1 macrolide export ATP-binding/permease MacB NC_012469.1.7685735. Protein 2e-61 57
TREPR_1666 YP_004531330.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 3e-38 43