Gene Information

Name : TREPR_2283 (TREPR_2283)
Accession : YP_004530786.1
Strain : Treponema primitia ZAS-2
Genome accession: NC_015578
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 1951205 - 1952773 bp
Length : 1569 bp
Strand : +
Note : identified by match to protein family HMM PF02384

DNA sequence :
GTGGCCAAACGCGCCCCCAAACCAGTCAAAGAACTCTCCCTCGAAAGCGTCCTCTGGAATTGCCGGGTAGTTTTGCGGAA
CAAATGCAACAAGCCGACCAACCGGGACGCCGTATTGGCCCTCATCTTCCTGAAATTTGCCGGTGACAAGTTTGAAAAAC
GGCGGCAGGAGATAATCGCCGAGGAAGGGGATATCCCGGTTTTCCTTGAAAAACCTTCGTTCTATCTGGCTTCCAATGTT
TTCTACCTTAACGAAACCTCCCGCTGGTCCTACATCGTAAAAAATGCAAGCGATGATAAAATAGCCGTCATGCTGGATCA
GGCAATGGCAGACATTGAAGATAAAAATGAATCCCTGAAAGGCGCCCTACCCCAGCGGTTTTTCTCCAGCCTGGGGGTAA
ACAGCAAGGATATAAAATCCCTCATCGACGAAATAAATAAAATATCAGAAGAACGGTTCCACGAAAAAGATTTAATCGGA
CGGGTCTACGAATATTTTTTACAACAGTTCGCCATGGATGAAGCAAAAGAAAAGGGAGAATTTTATACACCCAAGGCAAT
TGTCAATCTGATTGCCGAATTGATAGAACCCTATAAGGGCAGAATCTATGACCCCTGTTGCGGTTCCGGCGGCATGTTTG
TACAATCCCTCAAATTTGTAGAAAGCCATAATGGCAATAAAAATAACATATCCATCTTTGGGCAGGAATCCGATCCCGAT
ACCCGCAGGCTGGCTAAAATGAATCTGGCCATACGGGGCATATCAAATAACCTGGGGGATAAAAATGCCTCCTCCTTTAC
CGATGACCGGCAAAAGGATTTAAAAGTAGATTTTATCATGGCGAATCCTCCCTTCAACCTTAAGGCTTGGCGTGGTGAAG
ACGAATTAACCAATGATCCCCGCTGGTCAGGCTACGGTACTCCCCCGGTAAGCAATGCCAATTATGCCTGGATACTCCAT
ATACTTTCCAAACTTGATGTGAGTAACGGTATAGCGGGCTTTCTGCTTGCAAATGGCGCATTGGGAGCTGGGGCGGAAGA
ATACAATATTAGGAAACAACTTATTGAGAATGATAAAATAGAGGCAATAATTGTTCTGCCCCGTGAAATGTTTTACAGTA
CCGATATATCCGTAACCCTATGGATATTAAATAACAATAAGAAACCGCGAACCTTAAATAAACGAAAATTGCGGGACAGA
CAAAACGAAGTACTTTTTATTGACCTCCGCACATGGAATAAAAATGTATACGAAAAAAGTTATGTCACCTTTGATGATTC
ACAAATAGCTGCCGTCAAAAAAATCTATACCAATTGGCAAAGCGCCGAAAAGGGCTACAAAAATGTTCCAGAACTCTGTA
AATCCGTAAAAATAACGGACATACGAAAGAATGATTATTCCCTTGTGCCAAGCAAGTATATTAAGTTTATTGACCACGAT
TTGGATATAGATTACCAGAAAGAAATGAAAAGAATTCAAAAAGAGATGAAGGATATTTTGAAGGAGGAGAAGAAATCTCA
GGAAATGCTGGAATCCGCTTTTAAGGGAATCGGATATGGCATTAAATAA

Protein sequence :
MAKRAPKPVKELSLESVLWNCRVVLRNKCNKPTNRDAVLALIFLKFAGDKFEKRRQEIIAEEGDIPVFLEKPSFYLASNV
FYLNETSRWSYIVKNASDDKIAVMLDQAMADIEDKNESLKGALPQRFFSSLGVNSKDIKSLIDEINKISEERFHEKDLIG
RVYEYFLQQFAMDEAKEKGEFYTPKAIVNLIAELIEPYKGRIYDPCCGSGGMFVQSLKFVESHNGNKNNISIFGQESDPD
TRRLAKMNLAIRGISNNLGDKNASSFTDDRQKDLKVDFIMANPPFNLKAWRGEDELTNDPRWSGYGTPPVSNANYAWILH
ILSKLDVSNGIAGFLLANGALGAGAEEYNIRKQLIENDKIEAIIVLPREMFYSTDISVTLWILNNNKKPRTLNKRKLRDR
QNEVLFIDLRTWNKNVYEKSYVTFDDSQIAAVKKIYTNWQSAEKGYKNVPELCKSVKITDIRKNDYSLVPSKYIKFIDHD
LDIDYQKEMKRIQKEMKDILKEEKKSQEMLESAFKGIGYGIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-99 42
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-99 41
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 3e-100 41