Gene Information

Name : TREPR_2546 (TREPR_2546)
Accession : YP_004530534.1
Strain : Treponema primitia ZAS-2
Genome accession: NC_015578
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 1638240 - 1638923 bp
Length : 684 bp
Strand : -
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGATTACGCTAAGGGACATTTGGAAAAGCTACCCCATGGGAAAACTCGGCGTAGATGCCTTGAACGGGATTTCTCTGGA
ACTATCCAAGGGTGATTTTGTTTCCGTAGCCGGTCCTTCGGGTTCAGGAAAAACTACCCTAATGAACATTATCGGCCTCA
TTGATACCCCAAGCAGCGGCAGGGTACTTATCGACGGTAAAGAGACCGGGAACCTCCGCCGTAAGGAACTGACCCGCATA
CGGCAGGAAAGCATTGGGTTTGTATTCCAATCTTTTAATCTGCTGCCGGTTTTAACGGTTTTTGAGAATGTAGAACTTCC
CCTAACAATCGCACAAAAAAAGACTGCCCGTGCTGAACGACGGGAACGGGTTGAATACCTTTTGGAGGAAGTCGGGTTAG
GGGATAGGAAAACCCATAAGCCTTCAGAGCTCTCCGGCGGACAACAGCAACGTGTGGCTATCGCCCGGGCGTTGGTAACC
AGACCAAAAATAGTTATTGCCGATGAACCCACGGCAAACCTGGATTCCGCCAATGGGGAGCGGGTATTGGAACTTATGAA
AAAAATAAATCAGGAAGAGGGGACGACTTTTATTTTTTCAACCCATGATCCGGATATTTGGGAAATGGCTAATCACATTG
TTTTTTTAAAGGATGGTCGTATAGAATCGGAGAAGCGACGATGA

Protein sequence : 
MITLRDIWKSYPMGKLGVDALNGISLELSKGDFVSVAGPSGSGKTTLMNIIGLIDTPSSGRVLIDGKETGNLRRKELTRI
RQESIGFVFQSFNLLPVLTVFENVELPLTIAQKKTARAERRERVEYLLEEVGLGDRKTHKPSELSGGQQQRVAIARALVT
RPKIVIADEPTANLDSANGERVLELMKKINQEEGTTFIFSTHDPDIWEMANHIVFLKDGRIESEKRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1502 YP_001800896.1 cell division ATP-binding protein FtsE Not tested Not named Protein 5e-30 41
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-30 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 1e-30 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-30 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TREPR_2546 YP_004530534.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 3e-44 47
TREPR_2546 YP_004530534.1 macrolide export ATP-binding/permease MacB NC_008702.1.4606598. Protein 6e-33 46
TREPR_2546 YP_004530534.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 4e-37 43
TREPR_2546 YP_004530534.1 macrolide export ATP-binding/permease MacB CP001581.1.gene598.p Protein 5e-38 42