Gene Information

Name : fliI (TREPR_2555)
Accession : YP_004530526.1
Strain : Treponema primitia ZAS-2
Genome accession: NC_015578
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1628932 - 1630281 bp
Length : 1350 bp
Strand : +
Note : identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR03496

DNA sequence :
ATGGAAACCTTATTAGACAAGTATATTGAAACTGCGGAAGAAGTTGAAACCATAAAATACGTGGGCCATGTGATAAAGGT
CCAGGGTATACTCATAGAAAGTCTCGGCCCTTCCGCCGTGATAGGAGAAGTGTGCCGCATAGAAGTACCCCGGGGTAAAG
GGGTCATCCAGGCAGAAGTGGTGGGCCTCTCCAATGGCATAGTGCAGCTCATGGCCTACGAGGATATTGAAGGCATTGAG
ATAGGCAATAGGGTAGTGGCCTCAGGCGCTGCATTAGGGGTTGCAGTTTCCAACAAACTATTGGGCAGGGTCCTGGACGC
CATGGGCCGCCCCAGTGATGGGAAGGGCGAGATAGATTCCCCCCTGCAGTATCCTGCCATCGCCAGCCCCCCGCCCCCCC
TGAGCCGCAGACGTATTAAAGAGCGTATTGCAACCGGGGTGCGGGCCATAGACGGCATGTTAGCCGCAGGCCGTGGGCAG
CGTCTGGGGATCTTCGCCGGTTCCGGGGTGGGGAAGTCCACCCTCCTGGGCATGATAGCCCGGAACACCAATGCTGATGT
TAATGTTGTTGCCCTCATCGGAGAGCGGGGCCGGGAAGTCAACGATTTTATTGAAAATGATCTGGGCCCCGAAGGCCTGG
CCCGGAGCGTAATTATTGTAACCCCTTCTAATTCCCCCCCCCTGGCCCGGCTTCGGGGCGCCTACACTGCCACTGCGGTG
GCAGAATACTTCCGCGACCAGGGCCTGGACGTGATGCTCCTCTTTGACTCGGTCACCCGTTTCGCCCGGGCCCAGCGCGA
AATAGGCCTGGCAATCGGGGAACCCCCGGCCACCCGGGGCTATACCCCCAGCATGTTTGACTCCATGCCCAAGCTCCTGG
AACGCAGCGGCACTTCCGACCGGGGATCCATCACCGGCTTCTACACCATCCTGGTTGACGGGGACGACATGGACGAGCCT
GTGGCGGACACAGTCCGGGGTATCCTGGACGGCCACATCATCCTTTCACGGGACCTGGCTCAGCGTTACCATTACCCCGC
CATCGACGTGCTCACCAGCATATCCCGGCTGGCCCCCGCCGTATCCGGCCCGGTGACCAACAAAGCTGTGGGCTACATAC
GCCGGCTCATGGCGGACTATGCGGCGGCTGAGGACCTTATCAACGTGGGAGCCTACCGCACAGGCTCCAATCCAGCTATT
GATCAGGCCATCGCCAAGCGGGAGGCCATTGAGAATTTCCTCGTCCAGAATGTGGATGAAAAATCCACCATGAGCGAAAC
CCTAAAGACCCTGGCCGCCATAGCGGACATGCAGATCCCCGATGAAGAGCTGTCCCGGTACCGCGCATGA

Protein sequence :
METLLDKYIETAEEVETIKYVGHVIKVQGILIESLGPSAVIGEVCRIEVPRGKGVIQAEVVGLSNGIVQLMAYEDIEGIE
IGNRVVASGAALGVAVSNKLLGRVLDAMGRPSDGKGEIDSPLQYPAIASPPPPLSRRRIKERIATGVRAIDGMLAAGRGQ
RLGIFAGSGVGKSTLLGMIARNTNADVNVVALIGERGREVNDFIENDLGPEGLARSVIIVTPSNSPPLARLRGAYTATAV
AEYFRDQGLDVMLLFDSVTRFARAQREIGLAIGEPPATRGYTPSMFDSMPKLLERSGTSDRGSITGFYTILVDGDDMDEP
VADTVRGILDGHIILSRDLAQRYHYPAIDVLTSISRLAPAVSGPVTNKAVGYIRRLMADYAAAEDLINVGAYRTGSNPAI
DQAIAKREAIENFLVQNVDEKSTMSETLKTLAAIADMQIPDEELSRYRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-98 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-97 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-97 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-98 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-97 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-98 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-98 50
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-94 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-94 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-94 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 9e-91 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-71 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-87 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-87 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-81 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-81 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-81 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-81 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 7e-81 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-74 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-77 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-77 45
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-82 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 8e-76 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-77 44
escN AAC31513.1 L0034 Virulence LEE Protein 5e-84 44
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 5e-84 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-83 44
escN AAK26715.1 EscN Virulence LEE Protein 1e-83 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-83 44
escN AAL57542.1 EscN Virulence LEE Protein 1e-83 44
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-83 44
escN NP_290268.1 hypothetical protein Virulence LEE Protein 6e-84 44
escN CAI43874.1 EscN protein Virulence LEE Protein 8e-84 44
ECs4568 NP_312595.1 EscN Virulence LEE Protein 6e-84 44
escN AAC38383.1 EscN Virulence LEE Protein 6e-84 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-70 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-70 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-82 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-83 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-75 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-75 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-76 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-65 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-70 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-70 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-70 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG2144 Protein 8e-102 52
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG0048 Protein 1e-95 50
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG0390 Protein 3e-94 49
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG2331 Protein 6e-81 47
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG0192 Protein 5e-94 47
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG2499 Protein 2e-83 47
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG1254 Protein 3e-88 46
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG0515 Protein 1e-81 46
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG0730 Protein 4e-84 44
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG0812 Protein 3e-84 44
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG2459 Protein 2e-70 42
fliI YP_004530526.1 flagellar protein export ATPase FliI VFG0555 Protein 1e-70 41