Gene Information

Name : TREAZ_1835 (TREAZ_1835)
Accession : YP_004526084.1
Strain : Treponema azotonutricium ZAS-9
Genome accession: NC_015577
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD) family protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 528694 - 530175 bp
Length : 1482 bp
Strand : -
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGAAACCGAATTTTAAAAGCCCGTATCAGTTGTTTATCAATGGCAAATGGAAGGATGCTTCCGATGGAGCGGTCTACGA
TGTTTTCTCTCCCGCGACCGGGGAGAAGCTGGCTTCATGCGCCCAAGCGACTGCGGCAGATGTGGACGAGGCCGTTGTCG
GGGCGCAAAAGGCCTTTGAATCATGGAAGAAGACCAGCCCGGCTGAACGGGCCAAGGTCCTTACCAGTATTGGGGACATC
ATCAATAAGAACCTGGAAGAATTGGCCATAATCGAAACCCTGGATAACGGCAAGCCCATCCGGGAATCCATGAATATTGA
CGTGCCGGTTGCGGCGGAACACTATTACTACTTTTCAGGGGCAATCCAGGCCGAAGAAGGCTCCGCCGTCATGCTGGATG
ATCAGACATTAAGTTTAGTGCTGCGTGAACCCATTGGAGTGGTGGGACAGATTGTGCCCTGGAACTTCCCCCTTCTTATT
GCGTCCTGGAAAATAGCCCCTGCCCTTGCCTCGGGCTGCTGCGTGGTCATAAAGCCTTCAAGCTATACCAGCCTCAGCCT
GCTCCGCATGGCGGAACTTATCCAGGAAGTAGTGCCTCCCGGAGTCTTTAATGTGATCACCGGTTCCGGTTCCAAAGCCG
GGGAACATATGCTGAAGCATCCGGGCTTCGCCAAGCTCGCCTTTACAGGGTCCACCGAAATCGGCTGCCGTGTGGCTGAT
GCCGCTGCTGAAAAATTAATTCCCGCTACCCTCGAATTGGGGGGCAAATCGGCGAACATCTATTTTGACGACTGCAATTT
TGACAAAGCCCTGGACGGCCTGCAAATGGGCATACTCTTTAACCAGGGCCAGGTCTGCGCCGCAGGTTCCCGTGTCTTTG
TGCAGGAAGGGATCTACGACAAGTTTGTCAAAGCAGCGGCAGAAGCCTTCAACAAAATAAAAGTCGGCGACCCCTTGAGC
TCCACCACCCAGATGGGCGCATTGATCTACGAAGACCACCTCAAGGATGTGCTGAATTATATCGAGATTGGCAAAAGGGA
AGGCGCCAGGGTGATCGCAGGGGGCGAACGCATCATGGTGGGCAGTTTCGGCAAAGGCTTTTTCCTCCAGCCCACCCTCC
TTGCGGGTGTGACCAACAATATGCGAGTCGCCCAGGAAGAAATTTTCGGCCCCGTGGCGGTGATCACCAAATTCAAAACT
GAAGAAGAAGCGATCAGGCTTGCCAACGATTCCCAGTACGGATTGGCCGGCGGCGTCTGGACCCAGGATATCAACCGAGG
CATCCGCGTCGCCCGGGCTGTTGAGACCGGCCGCATGTGGATCAATATGTACAACGCCGTTCCTGCGGGCGCCCCCTTTG
GAGGCTACAAAAAATCCGGCATAGGCCGCGAAACCCACAAGGTCATTCTTGAACACTACACCCAGATGAAGAACATCATG
ATAAGCCTTGCCGAGGGACCTTCGGGATTCTATCCGGCATAG

Protein sequence :
MKPNFKSPYQLFINGKWKDASDGAVYDVFSPATGEKLASCAQATAADVDEAVVGAQKAFESWKKTSPAERAKVLTSIGDI
INKNLEELAIIETLDNGKPIRESMNIDVPVAAEHYYYFSGAIQAEEGSAVMLDDQTLSLVLREPIGVVGQIVPWNFPLLI
ASWKIAPALASGCCVVIKPSSYTSLSLLRMAELIQEVVPPGVFNVITGSGSKAGEHMLKHPGFAKLAFTGSTEIGCRVAD
AAAEKLIPATLELGGKSANIYFDDCNFDKALDGLQMGILFNQGQVCAAGSRVFVQEGIYDKFVKAAAEAFNKIKVGDPLS
STTQMGALIYEDHLKDVLNYIEIGKREGARVIAGGERIMVGSFGKGFFLQPTLLAGVTNNMRVAQEEIFGPVAVITKFKT
EEEAIRLANDSQYGLAGGVWTQDINRGIRVARAVETGRMWINMYNAVPAGAPFGGYKKSGIGRETHKVILEHYTQMKNIM
ISLAEGPSGFYPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-108 49
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-113 49
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-113 49
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-113 49
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-113 49
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-81 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TREAZ_1835 YP_004526084.1 aldehyde dehydrogenase (NAD) family protein VFG0082 Protein 9e-109 49