Gene Information

Name : TREAZ_1964 (TREAZ_1964)
Accession : YP_004525959.1
Strain : Treponema azotonutricium ZAS-9
Genome accession: NC_015577
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 408652 - 409353 bp
Length : 702 bp
Strand : -
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGAGTTTTGTTGAATTTCATGATGTATGTAAATTTTATCATCTTGGTGAACATACAATCGCCGCCGCAGATCGCATGAA
CTTCAACATCGAACAGGGTGAATTCTGTGTGATTGTGGGGCCCAGCGGCGCAGGCAAGACCACCTTGCTCAACATGCTGG
GAGGTATGGATTCCTGCGATCAGGGAACCATCATACTGGATGGCCAAGAAATCAGCGGCTTAAACGAGAAGCATCTTACC
GATTTCAGACGTTACGATGTGGGCTTTGTGTTTCAGTTTTACAATCTTATCCAAAACCTTACGGCCCTCGAAAATGTAGA
GCTTGCTTCGGAAATTTGCCATGAGCCCCATGATCCGCGCGAGACCCTGCAGGCGGTGGGGCTTGTGGAACGGCTGGACA
ATTTTCCGGCTCAGTTGTCAGGGGGTGAACAGCAGCGGGTTGCCATTGCACGGGCAATAGCGAAAAACCCCAAGATCCTC
CTCTGCGATGAACCCACCGGCGCCCTGGACTACGAAACAGGAAAGCATATCCTGGAACTCCTGCAAAACAGCTGCAAGAG
TACCGGCAAAACCGTCATCGTAATTACCCACAACCATGCTATCGCAGCTATGGCGGATCGGGTCATTCAAGTAAAAAACG
GCCAAATTATCAGCAATGAAAAAAACGAAAATCCCCTGGCGGTAGAATGTATTGAGTGGTAA

Protein sequence : 
MSFVEFHDVCKFYHLGEHTIAAADRMNFNIEQGEFCVIVGPSGAGKTTLLNMLGGMDSCDQGTIILDGQEISGLNEKHLT
DFRRYDVGFVFQFYNLIQNLTALENVELASEICHEPHDPRETLQAVGLVERLDNFPAQLSGGEQQRVAIARAIAKNPKIL
LCDEPTGALDYETGKHILELLQNSCKSTGKTVIVITHNHAIAAMADRVIQVKNGQIISNEKNENPLAVECIEW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-32 41
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-33 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 9e-33 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TREAZ_1964 YP_004525959.1 macrolide export ATP-binding/permease MacB NC_012469.1.7685735. Protein 3e-61 55
TREAZ_1964 YP_004525959.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 8e-41 42
TREAZ_1964 YP_004525959.1 macrolide export ATP-binding/permease MacB CP001581.1.gene598.p Protein 2e-41 41
TREAZ_1964 YP_004525959.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 6e-40 41