Gene Information

Name : TREAZ_2020 (TREAZ_2020)
Accession : YP_004525912.1
Strain : Treponema azotonutricium ZAS-9
Genome accession: NC_015577
Putative virulence/resistance : Resistance
Product : aminoglycoside 6-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.-
Position : 354311 - 355156 bp
Length : 846 bp
Strand : +
Note : identified by match to protein family HMM PF04439

DNA sequence :
ATGCGCAGCGAAAGAGAAATGATGGCCCTCATCCTCGGGGTTGCCCAAAAGGATGAGCGCATACGGGCAGTGTGGATGAA
TGGTTCGCGCACCAACACCAATGCTCCCAAAGATGATTTTCAGGATTACGATATTGTATACCTGGTAACAGAAAGGGAAT
CATTCATACGCGATCCGTCCTGGATAGATGTCTTTGGCAAACGGGTCATTCTGCAAACCCCCGAAGATATGTCCCTCTTT
CCATCCGAATATCCCGATACCTACGCATACCTCATGCAGTTTGAAGACAGGAACCGCATAGACCTTACCCTGGTTCCCCT
GGAATTTTTGGAACCCAATGTTAAGGGCGATAGATTGACAGTAATACTGTTGGACAAAGATAATCGTATTGATCCTATTC
CTCCTCCGTCTGATGAAGACTACCATGTCAAAAAACCCTCAGCCGCTTTTTATGATGATTGCTGCAATGAATTCTGGTGG
GTCTCGACCTATGTAGTTAAGGGTCTTTACCGGCATGAGTTCCTCTATGCGGCGAGTCATCTGAACAGCTGGGTAAGGGA
ACAGCTTCTGCAAATGCTCTCCTGGCAGGTTGGAATAGAAACCGGTTTTTCACTCAGCGTCGGGAAAAGTTATAAATACC
TCAGCAAACATCTTCCCGAAGAAACCTGGAAGCGCCTGAGGTCAACTTTTAAGATGGATACTGAAGAGAATATACGGACC
GCCTTTAACGAGACTTTGCAACTTTTCCGGGAATCCTCAAAACTGGTAGGAAAACACTTAGGCTTTGCTTATCCCGATTA
CGACGAAAAGGTTACTGCCTATATTGAAGGACTCAAATCCAGGTAG

Protein sequence :
MRSEREMMALILGVAQKDERIRAVWMNGSRTNTNAPKDDFQDYDIVYLVTERESFIRDPSWIDVFGKRVILQTPEDMSLF
PSEYPDTYAYLMQFEDRNRIDLTLVPLEFLEPNVKGDRLTVILLDKDNRIDPIPPPSDEDYHVKKPSAAFYDDCCNEFWW
VSTYVVKGLYRHEFLYAASHLNSWVREQLLQMLSWQVGIETGFSLSVGKSYKYLSKHLPEETWKRLRSTFKMDTEENIRT
AFNETLQLFRESSKLVGKHLGFAYPDYDEKVTAYIEGLKSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 9e-74 56
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 9e-74 56
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 4e-72 53
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 2e-49 52
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 1e-68 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TREAZ_2020 YP_004525912.1 aminoglycoside 6-adenylyltransferase AJ489618.1.orf2.gene Protein 4e-54 54
TREAZ_2020 YP_004525912.1 aminoglycoside 6-adenylyltransferase NC_006663.1.orf0.gen Protein 9e-65 53
TREAZ_2020 YP_004525912.1 aminoglycoside 6-adenylyltransferase FN594949.1.gene25.p0 Protein 2e-65 49