Gene Information

Name : pyk (TREAZ_3596)
Accession : YP_004527881.1
Strain : Treponema azotonutricium ZAS-9
Genome accession: NC_015577
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2574295 - 2576130 bp
Length : 1836 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGAAATCCATCAGAAACACCCGCATAGTCTGCACCATGGGGCCTGCCATAAAAACAATGGAAATGACCCGTTCCCTGAT
TCGCAAGGGCATGAACATAGCGCGCTTCAATTTTTCCCACGGCAGCCACGAGGAACACGCCATGCGGATTGTCATGGTGA
GGGAAGCCGCAAAGGCAGAGGGTGTTCCCGTTGCCTTGATTCTGGATACCAAGGGACCTGAAATACGCACCGGTGTTATT
AAGGACGATGGAGCAATAGACCTCAAAACCGGGACTCTCATTGACATAATTGCCGAGGAGGACGCGGCAAAACTTTCCGG
TGCCGATGGCGCCTATTCTACTACCAAGTGTATTACTGTCAGCTACAAGCTCCTTGCAGAGGATATTTTAAGTATTGACA
GCAATACTGCCAATGGAGATAAAAAAAAGAGCGTAAAAATACTGATTGCCGACGGTCTTATCGGCCTTGATGTATTGAAT
GTGGAAGGCAGAATAATTCACTGCAATGTTTCCAACGGCGGGGAACTGGGAAGCAGAAAGAATGTCAATGTCATAGGCGT
ACATACGAGGCTGCCCGCCATGTCCGAGAGGGACCAGGCCGACCTCCTTTTCGGGCACCAGCAGGGCATGGATTTTGTAG
CCGCTTCTTTTATACGCAAGGGCCAGGATGTCATCTCCATTAAAAAATATTTGACCTCCATAGGGTCTGATATGCCGGTG
ATCTCCAAAATCGAAGACGAGGAAGGGCTGGACAATATCGAAGAAATCATCCGCGTGTCGGACGGCATCATGGTAGCCCG
GGGGGACATGGGCGTGCAGATCCCCCCTGAGAGGGTGCCTTTGGAACAGAAGCGTATCATAAGCCTCTGCAACAGTGAGG
GAAAACCCGTCATAACCGCTACCCAGATGCTGGATTCCATGATTCACAACCCCAGGCCCACAAGGGCCGAAGCGGGAGAT
GTAGCGAACGCCATCCTCGACGGCACCGACTGTGTCATGCTTTCGGGAGAAACTTCCGCAGGGGCCTATCCTGAATTGGC
AGTAGAAGTAATGGATCGTATTGCGAGAACCACGGAAAATTCCGAAGCCTGCGGAGAAAGCCTTGACAGCCACCGCATAT
TCCCCAGGCATGGCTGCGACCTGGGCGAAGTGATCGCAAATTCAGCCAGCGAAACTGCCGACAGCATTAACGCCGCCTGC
ATTATTGTCCCTACCCTGTCAGGCCACAGCGCCCAGCTCATAAGCCGCTTCAAGCCCCGCAGGCCCATAGTGGCCGCCGC
GAGCAATGATTCTGTTGCCCGCCGACTCCTCCTTTACCGGGGCATAGTTCCCGTGGGGGTACAAAAAGTGGACGATTCCG
AAGCCATGATACAGGGCGCTATTACGGCGGCGATTAGAGAGGGTTTCGCGGGTCTTGCGGACAAAGTAGTTGTGGCGGCA
GGGCTCCCGGTCAATTCGCCCTTTACCTGCAACAGCATACGCATCCATGTGATAGGCAATATTTTGGGCCACGGACGCCG
AGGTTTCGGCGGACGCTGTACCGGAAGGATTTTCAAGGCTGACACCCTTACGGCCGCATCCCTGCTGCTGCATAAAAACC
GCGCCGAGATACTCCTCACCCATACCCTGGATGAATCATTTATTCCCATTATACGCATAGTGGACGGCATAATCCTTGAG
GGTATGTCCGAACTTTCCCAAAAGCAGCTTGAACTTATCAACCCTAAACTGGTTTACGTGGGCCAGGTTCCTGATGCGAT
AAAACACTTTGAAGACAATATCACCGTAACCCTGGATGGGGCTGAACGGACAATTTACGAGGGCAGTTTGTCCTGA

Protein sequence :
MKSIRNTRIVCTMGPAIKTMEMTRSLIRKGMNIARFNFSHGSHEEHAMRIVMVREAAKAEGVPVALILDTKGPEIRTGVI
KDDGAIDLKTGTLIDIIAEEDAAKLSGADGAYSTTKCITVSYKLLAEDILSIDSNTANGDKKKSVKILIADGLIGLDVLN
VEGRIIHCNVSNGGELGSRKNVNVIGVHTRLPAMSERDQADLLFGHQQGMDFVAASFIRKGQDVISIKKYLTSIGSDMPV
ISKIEDEEGLDNIEEIIRVSDGIMVARGDMGVQIPPERVPLEQKRIISLCNSEGKPVITATQMLDSMIHNPRPTRAEAGD
VANAILDGTDCVMLSGETSAGAYPELAVEVMDRIARTTENSEACGESLDSHRIFPRHGCDLGEVIANSASETADSINAAC
IIVPTLSGHSAQLISRFKPRRPIVAAASNDSVARRLLLYRGIVPVGVQKVDDSEAMIQGAITAAIREGFAGLADKVVVAA
GLPVNSPFTCNSIRIHVIGNILGHGRRGFGGRCTGRIFKADTLTAASLLLHKNRAEILLTHTLDESFIPIIRIVDGIILE
GMSELSQKQLELINPKLVYVGQVPDAIKHFEDNITVTLDGAERTIYEGSLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-78 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-78 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-78 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-77 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_004527881.1 pyruvate kinase VFG0479 Protein 6e-79 42