Gene Information

Name : TREAZ_0761 (TREAZ_0761)
Accession : YP_004527095.1
Strain : Treponema azotonutricium ZAS-9
Genome accession: NC_015577
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1719432 - 1721984 bp
Length : 2553 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
GTGTTTAAAGGTTTGACCCAGAGAGTGCAGAGGATAATTTCCATTGATGCCCAGGAAGAAGCCCGCCATTCCGGCGCGGA
TGAGCTTCTGCCTGAGCATGTGATCATCGCCCTTTTAAAAGACGGGGCCGGGACTGCCTGCAAGATTCTTCAGACCGCCA
AGGTGGACTCTGTGGAATTCATCCGGGCCCTGGAAACCACCCTGTCCCGTTCTTCGTCCATAATGGTGCGCGGGGATGTG
CCGCCTTCCAAACGCACTAAAATTCTCCTTGACACAGCCACCGACGAAGCCAGGATACTTGGCACTGATTATATAGGCAC
AGAGCATATACTTTTTGCGGCCCTGAGGGAAAAAGATTCCCTTGTGCATGCTTTTCTCCATCAGCTTGATGTGGAGCTGG
AATTCCTGCGGGTAATAGCCCAGACCACTTTTTCGAACCGGGGGAATTTTCCCAATGCCCAGGATATTTCCAGGGAGGCT
TCGCGGTCATCGTATGGCCATGAGCATCCTTTTTACGCGCGCAGGGAAGAGGGCAGGGACAATCCCCGGATTAGGACTGC
CTCTTACCCGGTGCTGACCCCGACCCTGGATGAATTCAGCCGGGATCTTACCGCGTTGGCCCGGGCAGGCAAGCTCGATC
CCATGGTGGGGCGCCAAAAGGAAGTTTCCAGGGCTCTGCGCATTTTGGCCCGGCGCAGCAAGAATAATCCGGTGCTGGTA
GGTGAACCCGGAGTGGGGAAGACCGCCATCGTGGAGGGCCTTGCCCAGCTCTTTGCGGGGAACATGGTTCCCCAGGCACT
GGCGGGGAAAAGGATACTTTCCCTGGACATGGGTTCCATTATAGCCGGAACCAAGTACCGGGGCGAATTCGAAGAACGCC
TCAAGAAGATCATGAGGGAGATAGGCCAGGCCAAGAATGTCATCCTTTTTATCGACGAGATCCACACAGTGATAGGGGCA
GGGGGGGCGGAAGGGACCATCGATGCGTCCAATATGCTCAAGCCCGGTCTTTCCCGGGGCGAGATCCAGTGCATAGGCGC
AACCACCCTGGCCGAATACCGCAAGCATTTCGAGAAAGACGCTGCCCTGGAACGCCGTTTCCAATCCATACTGGTGGAAG
AGCCCAGCCTGGACGAAACCATCGAAATACTCGAAGGCATTAAGAAACACTACGAAGAGCATCACGGGGTGACCTATACC
CCCGAGGCAGTGGACGCTGCGGCCCGGCTTGCCCAGCGCTATATCACTGGCCGCTTTATGCCCGACAAAGCCATCGACAT
ATTGGACGAGGCAGGGGCCATGAAGAAGCTCGCCCCTCCCGTTATCCCGCCGGAAATTTCGGGCCTCGAAGACGAGATAC
GGAAGCTCACCGATGAAAAGGTATTCATGGTGACAGCCCAGGATTACGAAGGCGCAGCTGAACTCAGGGACAAGGTGAGG
GGCCTCCGGGGCCGGCTCGAAACCATGAAGGTCGCCTGGGAGCAGAGCACCAGGGCAGAAAAGCTCAAAGTAGACGAGGC
TGACATAAGGCGCATAGTGGCTGAGATTACCGGCATTCCCCTGACCCATCTTGAAGAACAGGAATCCCGGCGTCTCCTTA
AAATCGAAGAAGAACTCCACCGGGGGGTTATTGGCCAGGACGATGCAGTAAAGCGCATTGCTTCTTCCATACGGCGCTCA
CGGGTGGGGATCTCGAACCCCCACAGGCCCATGGGTTCCTTTATCTTTTTGGGGCCTACAGGCGTCGGCAAGACCCTCCT
GGCAAAGCGGCTTTCAGAATATCTCTTTCAAACCCCCGAATCCCTGGTACGCATAGATATGTCGGACTATATGGAGAAGC
ACAATGCTTCCCGCCTTGTCGGCGCGCCTCCGGGCTATATCGGCTATGAAGAGGGCGGGGTGCTTACGGAAAAAATACGC
CGCAACCCCTATAGGGTGGTGCTTTTTGACGAGATCGAAAAAGCCCACCGGGATGTTTTCAACCTTCTTTTGCAGGTACT
TGAAGAGGGCGAGCTTAAAGACAACCTGGGCCATACCATAAGCTTCCGCAACACGGTTATTATCATGACCAGCAACGCGG
GGGTACGGGAAATTTCAAAAGATTCGCGCCTTGGCTTCGGCGCCGGGAGCGGCCTCATGAGCTTCCAGGAAATAGAATCC
CAGGCGCTCTCCGAGCTCAAGCGTTTCCTTAACCCCGAATTCCTGAACCGTGTTGACGATGTGGTGGTCTTCCATCCCCT
GGAAAAGGAACAGGTTGAATCCATCCTCGGCCTGCAGCTTGACGAACTTGGCCAGCGTATGGCAGAGCAGGGCTATGCAA
TCGAAGTCGATCCCTCGGCCCGTTCCATACTCATAGAAAAAGGCTGGGATCCCAAATTCGGCGGAAGGCCCTTGCGCAGG
GCAATTCAGAAGGAACTGGAAGATCCTATTTCCCTTAAGATACTGGAAGGGGGTTTGCCCATAGGCACATCTTTCAAAGC
CGAGGGGGAAAACGGGAAGATTCTTTTGACTGTCCAGGCACTTCCTGTAGAATCCGGAAGCCTAACGCTTTAA

Protein sequence :
MFKGLTQRVQRIISIDAQEEARHSGADELLPEHVIIALLKDGAGTACKILQTAKVDSVEFIRALETTLSRSSSIMVRGDV
PPSKRTKILLDTATDEARILGTDYIGTEHILFAALREKDSLVHAFLHQLDVELEFLRVIAQTTFSNRGNFPNAQDISREA
SRSSYGHEHPFYARREEGRDNPRIRTASYPVLTPTLDEFSRDLTALARAGKLDPMVGRQKEVSRALRILARRSKNNPVLV
GEPGVGKTAIVEGLAQLFAGNMVPQALAGKRILSLDMGSIIAGTKYRGEFEERLKKIMREIGQAKNVILFIDEIHTVIGA
GGAEGTIDASNMLKPGLSRGEIQCIGATTLAEYRKHFEKDAALERRFQSILVEEPSLDETIEILEGIKKHYEEHHGVTYT
PEAVDAAARLAQRYITGRFMPDKAIDILDEAGAMKKLAPPVIPPEISGLEDEIRKLTDEKVFMVTAQDYEGAAELRDKVR
GLRGRLETMKVAWEQSTRAEKLKVDEADIRRIVAEITGIPLTHLEEQESRRLLKIEEELHRGVIGQDDAVKRIASSIRRS
RVGISNPHRPMGSFIFLGPTGVGKTLLAKRLSEYLFQTPESLVRIDMSDYMEKHNASRLVGAPPGYIGYEEGGVLTEKIR
RNPYRVVLFDEIEKAHRDVFNLLLQVLEEGELKDNLGHTISFRNTVIIMTSNAGVREISKDSRLGFGAGSGLMSFQEIES
QALSELKRFLNPEFLNRVDDVVVFHPLEKEQVESILGLQLDELGQRMAEQGYAIEVDPSARSILIEKGWDPKFGGRPLRR
AIQKELEDPISLKILEGGLPIGTSFKAEGENGKILLTVQALPVESGSLTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-173 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TREAZ_0761 YP_004527095.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 3e-153 49
TREAZ_0761 YP_004527095.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 47