Gene Information

Name : fliI (TREAZ_0888)
Accession : YP_004526981.1
Strain : Treponema azotonutricium ZAS-9
Genome accession: NC_015577
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1572279 - 1573739 bp
Length : 1461 bp
Strand : +
Note : identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR03496

DNA sequence :
ATGCCAGCCCTTATGGAAATTGGACACTCCGCCGAGATCCGCCAGGATCGCGGTTTCCCTCCGGATATAATAAAAAAATA
CCTCGAAACTACCGAAAGCATCGACCCCATTAAATGCATAGGCCGCATCAGCAAAGTCCAGGGCCTTCTTATAGAAAGCC
GGGGCCCCCAGGCTATCATAGGCGAAATATGCCGCATCGAAGCGCCGAAAGGCGCAGGTCTCATACGGGCGGAAGTGGTG
GGCCTTAGGGGCGACACAGTCCAGCTCATGGCATACGATGAAACCGACGGCCTTGAGATAGGCGCCAGGGTAGTCGCGTC
AGGTACGCGCCTTGAAGTGGCTGTTTCCAACAAACTCCTTGGCCGTGTCCTCGATCCCCTTGGGCATCCGGTTGATGGCA
AGGGCAATATCGAATCCCCGGTGCATTATCCGGCCCTTGCCAATCCTCCTGACCCTTTGAAGCGCAGGCGCATCACCGAG
CGCATCAGTACCGGCGTGCGCGCAATTGATGGTATGCTCGCGGTGGGCCGGGGCCAGCGGCTTGGCATTTTTGCAGGTAC
CGGTGTTGGCAAGTCCACACTCCTTGGCATGATTGCCAGAAACACTAACGCTGATGTCAATGTCATTGCCCTGATCGGCG
AACGGGGCAGGGAAGTGAACGATTTTATCGAAAACGATCTTGGCCCCAACGGCCTGGCCCGCAGCGTCATTGTGGTAACC
CCTTCCAATTCTCCTCCCCTGGCGCGGCTTCGCGGGGCTTATACAGCTACCGCAGTGGCCGAATATTTTAGGGATCAGGG
CCTGGATGTGATGCTCCTCTTTGACTCCGTAACCCGCTTTGCCAGGGCCCAGCGTGAAATAGGCCTTGCCACAGGCGAGC
CCCCCGCAACCCGGGGCTTTCCCCCCTCCATGTTTGATTCCATGCCCAAGCTCCTTGAACGCTGCGGTACTTCGGACCGG
GGAACCATCACGGGCTTTTATACCATACTGGTAGACGGCGATGACATGGACGAGCCTGTCGCGGACACCGTGCGGGGCAT
ACTGGACGGGCATATTGTCCTGTCCCGCAGCCTTGCGCAGCGTTACCATTACCCGGCCATCGATATCCTTAACAGCATTT
CCCGTCTTTCGACTGCGGTGTCTGGGTCCGAAACCAAAAAAGCAGTGGGAATTATCCGCCGCCTCATGGCCGATTATGCT
GATTCCGAGGATCTTATCAATGTGGGCGCTTACAAACAGGGATCAAATCCAAAAATAGACGAGGCCATAGCCAAGCGTGA
CGCCCTTGAGAATTTTTTCATTCAGAATGTGGATGATAAGTCTTCCATAGTTGACACCCTCAATGCATTGGGAAAAATCG
CCGGTGTTGAAATCCCCGAAAGCGAAATGGAAGTGTTCCTGCCCAAGATGGTTTTTTCGATGAATAACAATGAAGACGCG
GAATTCCAGGGCAATGCATGA

Protein sequence :
MPALMEIGHSAEIRQDRGFPPDIIKKYLETTESIDPIKCIGRISKVQGLLIESRGPQAIIGEICRIEAPKGAGLIRAEVV
GLRGDTVQLMAYDETDGLEIGARVVASGTRLEVAVSNKLLGRVLDPLGHPVDGKGNIESPVHYPALANPPDPLKRRRITE
RISTGVRAIDGMLAVGRGQRLGIFAGTGVGKSTLLGMIARNTNADVNVIALIGERGREVNDFIENDLGPNGLARSVIVVT
PSNSPPLARLRGAYTATAVAEYFRDQGLDVMLLFDSVTRFARAQREIGLATGEPPATRGFPPSMFDSMPKLLERCGTSDR
GTITGFYTILVDGDDMDEPVADTVRGILDGHIVLSRSLAQRYHYPAIDILNSISRLSTAVSGSETKKAVGIIRRLMADYA
DSEDLINVGAYKQGSNPKIDEAIAKRDALENFFIQNVDDKSSIVDTLNALGKIAGVEIPESEMEVFLPKMVFSMNNNEDA
EFQGNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-103 51
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-104 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-104 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-104 51
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-104 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-105 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-105 51
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-101 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-101 50
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-97 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-90 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 8e-88 47
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-88 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-87 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-87 47
escN AAC38383.1 EscN Virulence LEE Protein 2e-87 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-88 47
escN AAC31513.1 L0034 Virulence LEE Protein 8e-88 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-87 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-86 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-86 46
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-87 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-87 46
escN AAK26715.1 EscN Virulence LEE Protein 2e-87 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-88 46
escN AAL57542.1 EscN Virulence LEE Protein 2e-87 46
escN CAC81862.1 EscN protein Virulence LEE II Protein 9e-88 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 4e-85 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 6e-86 45
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-86 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-86 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-86 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-80 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-80 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-74 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-77 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 8e-77 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-77 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-76 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-79 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 7e-79 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-74 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-74 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-70 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-70 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-70 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-70 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-70 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG2144 Protein 2e-104 54
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG0048 Protein 2e-98 49
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG1254 Protein 2e-91 49
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG0192 Protein 6e-98 48
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG0390 Protein 3e-98 48
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG2499 Protein 5e-87 48
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG2331 Protein 1e-83 47
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG0730 Protein 1e-87 47
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG0812 Protein 4e-88 47
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG0515 Protein 9e-87 45
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG2459 Protein 3e-77 43
fliI YP_004526981.1 flagellar protein export ATPase FliI VFG0555 Protein 6e-71 41