Gene Information

Name : mbtA (JDM601_1528)
Accession : YP_004522782.1
Strain : Mycobacterium sp. JDM601
Genome accession: NC_015576
Putative virulence/resistance : Virulence
Product : bifunctional salicyl-AMP ligase/salicyl-S-ACP synthetase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1652267 - 1653808 bp
Length : 1542 bp
Strand : -
Note : -

DNA sequence : 
TTGGACTCGATCCTCACCGAGGCGGCGAGCAACTGGCCACAGCGGCCCGCTGTCATCGATGCGGGCCGCAGCTATTCCTT
TGCCGAACTCGATTCGGCTGCTGACCGATTCGCGGCAGGCCTGGCGCGGCTCGGCATCGCTGCGGGCGATCGTGTACTGC
TTCAGCTGCCGAACTCGACGCAATTCGCGCTGGCGTTTTTCGGCGTATTGCGGGCCGGCGCCGTGCCGGTGATGTGCTTG
CCGGGTCACCGTGCCGCCGAGCTGGGCCACTTCGCCGACGTGAGTGACGCGGTGGCTCTGATAATCGCCGACCGTGCAGG
CGGTTTCGACTACCGCGAACTTGCCGCGCGCGTCACCGAGGGCCGCTCGAGGCTGCAGCACGTCATCGTCGATGGAGATC
CCGGACCGTTCACTGTGTGGTCGACAGTCGCCCAATGCGCAGGCCCCGCCGTCCAGCGTGCCGATGTCGACACCACCACG
CCCGCTCTGCTGCTGGTATCGGGCGGTACGACCGGCATGCCCAAGCTCATTCCCCGCACCCATGACGACTACCTCTACAA
CACGACGGCCTGCGCTCAGGCGTGCGGACTGACCGGGGACGACGTCTACCTGGTGGCGCTGCCCGCCGGTCATAACTTTC
CGCTGGGATGCCCGGGAATGTTGGGCGCGATGACGGTGGGCGCCGCCACGGTGTTCACCGCCGATCCCAGCCCCGAAGCC
GCTTTTGCGCTGATCCACCGGCACGGCGTGACCGCTACCGCGTTGGTCAACGCCTTGGCGAAGTTGTGGGCGCAGGCCTG
CGATTGGGAGCCGAACCCGCCGACAGCGCTGCGATTGCTGCAAGTGGGTGGATCACGGATGGCGCCCGACGAAGCCCGCT
ATCTCCGAGAGACCCTGGGTCCGGGACTGCAGCAGATTTTCGGAATGGCCGAGGGGATGCTGAATTTCACTCGCCCCGGC
GACCCCGTCGAGGTCGTCGAGCAGACCCAGGGCCGGCCGATGTCACCGCACGACGAACTGCGCGTCGTGGACGACAACGG
CGAGGACGTGGCCCCGGGCGAGGAAGGCGAACTGCTGGTCCGCGGACCGTACACCCTCAACGGCTACTACCGGGCGGATC
AGGCCAATGCGCGGTCGTTCAGCCCCGATGGATTCTTCCGGACCGGAGACCAGGTGCGTATCTTTGCCGACGGTCCGCTC
GCCGGCAACGTCGAAGTCACCGGGCGGATCAAGGACGTGATCCACCGTGGCGGGGAGACCGTTTCGGCGTCCGACATCGA
GGAGCACATCCTTACCCATCCGGCCGTCTCGGCTGCCGCGGCGATCGCGCTGCCAGATGAATTTCTGGGTGAAAAGATCT
GCGCCGCAGTGATCTTCAAGAGCGAACAGATCTCCCTCGCCGAACTCAACCGCCACCTGGACGAGCGCGGAGTCTCTGCC
CATTCGCGCCCGGACATGCTCGTTGCGATGCCCTCGCTGCCCATCACCGCCGTCGGGAAGGTCGACAAGAAGCAGATCGT
CGCCCAGGTGGGCAGCAGATGA

Protein sequence : 
MDSILTEAASNWPQRPAVIDAGRSYSFAELDSAADRFAAGLARLGIAAGDRVLLQLPNSTQFALAFFGVLRAGAVPVMCL
PGHRAAELGHFADVSDAVALIIADRAGGFDYRELAARVTEGRSRLQHVIVDGDPGPFTVWSTVAQCAGPAVQRADVDTTT
PALLLVSGGTTGMPKLIPRTHDDYLYNTTACAQACGLTGDDVYLVALPAGHNFPLGCPGMLGAMTVGAATVFTADPSPEA
AFALIHRHGVTATALVNALAKLWAQACDWEPNPPTALRLLQVGGSRMAPDEARYLRETLGPGLQQIFGMAEGMLNFTRPG
DPVEVVEQTQGRPMSPHDELRVVDDNGEDVAPGEEGELLVRGPYTLNGYYRADQANARSFSPDGFFRTGDQVRIFADGPL
AGNVEVTGRIKDVIHRGGETVSASDIEEHILTHPAVSAAAAIALPDEFLGEKICAAVIFKSEQISLAELNRHLDERGVSA
HSRPDMLVAMPSLPITAVGKVDKKQIVAQVGSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-92 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-92 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-92 43
ybtE CAA21394.1 - Virulence HPI Protein 3e-92 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-93 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-92 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-93 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 4e-92 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-92 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mbtA YP_004522782.1 bifunctional salicyl-AMP ligase/salicyl-S-ACP synthetase VFG1817 Protein 4e-158 65
mbtA YP_004522782.1 bifunctional salicyl-AMP ligase/salicyl-S-ACP synthetase VFG0168 Protein 1e-84 44