Gene Information

Name : metB (JDM601_1025)
Accession : YP_004522279.1
Strain : Mycobacterium sp. JDM601
Genome accession: NC_015576
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1098454 - 1099599 bp
Length : 1146 bp
Strand : +
Note : -

DNA sequence :
TTGCACGGCCCGATCGGCCCCTCCACGACGGCGATCCATGCCGGTTTCCGGCCCGATCCGGCCACCGGGGCGGTCAATCC
GCCGATCTACGCGAGCAGTACGTTCGCCCAGGACGGCGTCGGTGGGCTGCGGGGCGGTTACGAGTACGCCCGCACCAGCA
ACCCGACCCGGACCGCGCTGGAGACCGCACTGGCCGCCGTCGAGCAGGGCCGATACGGCCGGGCGTTCTCCTCCGGGATG
GCCGCCACGGACTGCGCGCTGCGGGCGATGCTGCGTCCCGGTGATCATCTGATCATCCCCGACGACGCCTACGGCGGCAC
CTTCCGGCTGATCGACAAGGTGTTCACCGGTTGGGGTTTGGCCTACACGCCGGTCGCGCTGTCCGACCTGGATGCAGTGC
GTGCCGCACTCACCGACAAGACCCGACTGATCTTGGTGGAGACGCCCACCAACCCGTTGCTGTCGATCAGCGACATCGAA
AGCATTGCCGCAATCGGCCGGGAGTCGGGCGCAAAGGTGTTGGTGGACAATACGTTCGCCTCGCCGGCGCTGCAGCAGCC
GCTGACGCTGGGCGCTGACGTGGTGCTGCACTCCACCACGAAGTACATCGGCGGCCACTCCGATGTGGTCGGTGGCGCGC
TGGTCACCGACGACGAGGAGCTCGACGCCGCCTTCGCGTTCCTGCAGAACGGCGCCGGGGCGGTCCCCGGTCCGTTCGAC
GCCTACCTCACGCTGCGGGGCCTCAAGACGCTGGTGCTGCGGATGCAGCGGCACAGCGAGAACGCGGCCGCGGTGGCGGA
GTTCCTTGCCGGACACGCCGCCGTCGACACCGTGCTGTATCCGGGCCTGCCCGGCCACCCGGGGCACGACATTGCCGCGC
GCCAGATGCGCGGGTTCGGTGGCATGGTGTCGGTGCGGCTGCACGGCGGTCGGGGAGCTGCGGAGAAGCTGTGCGCCGCA
ACCGAGATCTTCATCCTGGCCGAGTCACTGGGCGGGGTGGAGTCGCTGATCGAACACCCGGGCGCGATGACCCATGCGTC
GACGGCCGGTTCGCAACTGGAGGTTCCCGACGACCTGGTGCGGCTCTCGGTCGGCATCGAGGACATCGACGACCTGCTCG
AGGACCTGAAGCAAGCGCTGCGCTGA

Protein sequence :
MHGPIGPSTTAIHAGFRPDPATGAVNPPIYASSTFAQDGVGGLRGGYEYARTSNPTRTALETALAAVEQGRYGRAFSSGM
AATDCALRAMLRPGDHLIIPDDAYGGTFRLIDKVFTGWGLAYTPVALSDLDAVRAALTDKTRLILVETPTNPLLSISDIE
SIAAIGRESGAKVLVDNTFASPALQQPLTLGADVVLHSTTKYIGGHSDVVGGALVTDDEELDAAFAFLQNGAGAVPGPFD
AYLTLRGLKTLVLRMQRHSENAAAVAEFLAGHAAVDTVLYPGLPGHPGHDIAARQMRGFGGMVSVRLHGGRGAAEKLCAA
TEIFILAESLGGVESLIEHPGAMTHASTAGSQLEVPDDLVRLSVGIEDIDDLLEDLKQALR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-69 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-70 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-53 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_004522279.1 cystathionine gamma-synthase BAC0207 Protein 7e-61 44