Gene Information

Name : Desku_2425 (Desku_2425)
Accession : YP_004517760.1
Strain : Desulfotomaculum kuznetsovii DSM 6115
Genome accession: NC_015573
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 2422313 - 2424703 bp
Length : 2391 bp
Strand : -
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain, subgroup; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: mta:Moth_0349 DNA topoisomerase; PFAM: DNA topoisomerase, type IA, central; Toprim domain

DNA sequence :
TTGCGCAAGCTGGTTATAGCCGAGAAACCGTCCGTCGCCCGCGACATTGCCTCCGCCCTGGGGAAATTCGCGCAAAAAGA
CGGCTACCTGGAGAACGACCGTCTGGTCATCTCCTGGGCGCTGGGCCACCTCCTGGAACTGGCCGACGCGCACGAATACG
ACCCGGCCTTCGTCAAGTGGACTCTTGAACCGTTACCCATTATCCCGGAGGAGTTCAAACTGCATCCAATCAGGAGTGGT
GCGAAGCAGCTCAAAATCCTGAAACAACTGCTCAATTCGGCGGACGTGGCGGAAGTAATCAACGCCTGTGACGCGGGGCG
TGAGGGGGAACTGATCTTCCGCCGCATATACGAGTGGTGCGGCTGCAGAAAACCGGTCAAACGCCTGTGGCTTTCGGAGG
CCACCCCCTCCGCAATCCGGGAGGCCTTCAAAAAACTCCGTGACGGCCGCGAACTGGACAACCTGGCAGCGGCGGCCAGG
GCCCGGGCCGAAGCCGACTGGATCGTGGGGATCAACGCCACCCGGGCGTTTTCGGTGAAACACAAAACCCTGCTCTCCGT
CGGCAGGGTACAGACACCCACCCTGGCCCTGGTGGTGCAGCGGGAAAGGGAAATCCGGGATTTCAAGCCGGAGACTTACT
GGGAGGTCCGGGCCACCTTCCAGAAAAGCGGCGGGGCCACCTACCGGGGCAGGTGGTTCAGGGGTGGCGAGAGCCGCATC
AAAGAAAAATCACGGGCAGAGGAACTGGTACGGGCCGCCCTGGCCGCCGGTTCCGGCAGGGTGGCACAGGTTGAAAAACG
CACTAAAACGGAGGCCCCACCCCTGCTCTTCAACCTGAACGACCTGCAGAAAGAAGCCAACCGGAAATACGGAATGACGG
CTCAGAAGGTCCTGGACGCGGCCCAGGCCCTCTACGAAAAACACAAACTGATCACCTATCCCAGGACGGACAGCCGCCAT
TTAACGGAGGCATTGGCGCGGGACACCCTGCAAAAACGCCTGGCCGCTCTGGAAAAATGCCCGGAATACGGGGAACTGAT
CCGCCGGATCAGGCCGGGAATGCTCCCGGGCAAACGTTACATCGACGACGCCGGAGTCACGGACCACCACGCCATCATCC
CCACGGACGTGACTCCGGACCCGTCAGCCCTCAACCCCGCGGAGCGACAGGTATATGATCTGGTGGTCCGGAGGTTCCTG
GCCATGTTTTATCCCCCGGCAGTCTACGACGAAACCGCCGTGGTCACCGAAGTCGGGGACGAGACTTTTATATCCAGAGG
CCGGGTAGAGATCGAGCCGGGCTGGAAAGCAGTATACGGGCCGGAAGAAAAGGAGGAAAAGGATGGGAAAGACGAAGACG
GAGAATCACAACCGCTCCCGCCCCTGGCCGAGGGCGAGACGGTCGGCGTCGAAGAAGCGGGGGCTGTCGAGCGGCAGACG
AAACCCCCGAAACGGTACACCGAAGCCACGCTTCTGGCGGCCATGGAAAATGCCGGCCGCCTTTTGGACGACAGGGAAAT
GGCCGAAACCCTCAAGGCCGCCGGCGGCATCGGCACACCCGCCACCAGGGCGGCAATCATCGAAACGCTGATCAAGCGGG
GATACATCGAGCGCCGCAAGAAAACCCTGGTGCCCACCCCGCGGGGCGAAGCACTGATAGACCTGGTGCCGGAAAAACTG
AAATCGGTGGAACTGACCGCTCAATGGGAAGACGGGCTGCGGCGTATAGAGGAGGGGCTGGATGATGCCCGGTTGTGGCT
GGTTGGCCTCAAAAACTTCACGGTGGAGGTGGTGGCCATGGCAAAAGAACAGGAAGCAAACGGCGCGGTACACCAGAAGG
AGGTGATGGGCAGGTGTCCTCTATGCGGACGTGACGTGCTGGAATATACCAAATCCTACGGCTGCAGCGGGTACAGAGAC
GGATGTAACTTTGCCATCTGGAAGGAAACCGCCGGAAAGAAGATTACGGCCAAACAAGCACGGGAGTTACTCCAAAAAGG
CAGAACCGGCGTAATTAAGGGCTTCAAATCCAAAGCCGGCAAGAGTTTCGACGCCATATTGACCCTGGGGGAAGACGGCA
AAGTCAACTTCGAATTTGCCGACCACGCCGGCCAGGCCCTGGGCAAATGTCCCCTCTGCGGCAAGGATGTCATCGAGGGG
AAGAAGGGCTACGGCTGCGCGGGATGGAAGGAGGGTTGTAAATTCGTTATCTGGAAGGAGATCGCCGGGAAAAAGATTGC
GGCCAACCTGGCAAAAGAACTGCTCCAGAAGGGCAGGACCGGCGTTATCAAGGGCTTTAAGTCCAGGGCCGGCAAGGACT
TCGAAGCCGCCCTGGTCCTGGGAGAAGGCGGCAAAATAGAATTCGAGTTTAAAAACCGACAGGAGGGATAG

Protein sequence :
MRKLVIAEKPSVARDIASALGKFAQKDGYLENDRLVISWALGHLLELADAHEYDPAFVKWTLEPLPIIPEEFKLHPIRSG
AKQLKILKQLLNSADVAEVINACDAGREGELIFRRIYEWCGCRKPVKRLWLSEATPSAIREAFKKLRDGRELDNLAAAAR
ARAEADWIVGINATRAFSVKHKTLLSVGRVQTPTLALVVQREREIRDFKPETYWEVRATFQKSGGATYRGRWFRGGESRI
KEKSRAEELVRAALAAGSGRVAQVEKRTKTEAPPLLFNLNDLQKEANRKYGMTAQKVLDAAQALYEKHKLITYPRTDSRH
LTEALARDTLQKRLAALEKCPEYGELIRRIRPGMLPGKRYIDDAGVTDHHAIIPTDVTPDPSALNPAERQVYDLVVRRFL
AMFYPPAVYDETAVVTEVGDETFISRGRVEIEPGWKAVYGPEEKEEKDGKDEDGESQPLPPLAEGETVGVEEAGAVERQT
KPPKRYTEATLLAAMENAGRLLDDREMAETLKAAGGIGTPATRAAIIETLIKRGYIERRKKTLVPTPRGEALIDLVPEKL
KSVELTAQWEDGLRRIEEGLDDARLWLVGLKNFTVEVVAMAKEQEANGAVHQKEVMGRCPLCGRDVLEYTKSYGCSGYRD
GCNFAIWKETAGKKITAKQARELLQKGRTGVIKGFKSKAGKSFDAILTLGEDGKVNFEFADHAGQALGKCPLCGKDVIEG
KKGYGCAGWKEGCKFVIWKEIAGKKIAANLAKELLQKGRTGVIKGFKSRAGKDFEAALVLGEGGKIEFEFKNRQEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB-2 NP_815968.1 DNA topoisomerase III Not tested Not named Protein 6e-104 41