Gene Information

Name : Desku_1651 (Desku_1651)
Accession : YP_004517030.1
Strain : Desulfotomaculum kuznetsovii DSM 6115
Genome accession: NC_015573
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1646349 - 1648100 bp
Length : 1752 bp
Strand : -
Note : TIGRFAM: Pyruvate kinase; KEGG: pth:PTH_2214 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region

DNA sequence :
TTGAGACGAACCAAAATAATCTGCACCATCGGTCCAGCCTGCGAACAGGTAGAAACCCTCATGGAAATGATGCGGGCAGG
CATGAATATAGCCAGGCTTAATTTCTCCCACGGCACCCACGAAGAACACGCCCGGCGTATTGCCAATATACGGGAGGCTG
CTGGCCGGGTGGGTAAAAATATTGCCATTTTGCTGGACACAAAAGGGCCGGAAATTCGCCTTGGTTACCTTGAAAAGGAA
CCCGTAGTGCTTAAAGCCGGTCAGCGGGTGGTCCTTACCACCGAGAACATCAAGGGCACTCCGGAACGCCTGCCCATTAC
CTATGCCGGATTGCCCCGGGACGTGGCCCCGGGAAATACCGTCCTGATTGCCGATGGACTCATAGAGCTGCGGGTAATAG
GCAGCAACGGGCATGAAGTGGAATGTGAGGTGGTTCACGGGGGGGAATTGACCAGCCAGAAGGGGGTCAATCTTCCCGGG
GTGCCGGTGAACCTGCCCGCCATTACCGAGCAGGACATCCGGGACATCAAGTTCGGCATTGAGCAGGAACTGGATTTTAT
CGCCGCCTCTTTTATTCGCAGTGCTTCAGATGTGCTGGCCATCCGCCGCATCCTGGAAGAACATGGGGCGGACATGGACA
TTATCGCCAAGATTGAAAGCAAAGAAGGCGTGGAAAACCTGGATGAAATTATCAAGGTAGCCGACGGCATCATGGTGGCC
CGGGGTGATTTAGGGGTTGGCCTTCCGGTGGAGGAAGTACCTCTGATCCAAAAAGCCATCATTGAAAAATGCAATCTGGC
CGGAAAACCGGTCATTACCGCCACCCAGATGCTGGAATCAATGATTCACAACCCCCGTCCTACCCGGGCCGAGGCCAGCG
ACGTGGCCAACGCCATCCTGGACGGCACCGATGCCATTATGCTCTCGGGAGAAACAGCCGCGGGGCACTATCCGGTGGAG
GCTGTAAAAACCATGGCCCGCATTGCCAGCCGGGTGGAGAAAGCCCTCCCCTACGAAGAGATTCTACAACGGCGGGGCCG
GGCGCTGGCCCGCACGGTCACCGATGCCATCAGCCACGCCACCTGTACTACCGCCCAGGACCTGGGAGCCGCCGCCATCA
TTACCTCCACGGAGACAGGCTATACGGCCAAGATGGTGAGCAAATACCGTCCCCGGGCGCCGATCATAGCCGTGACGCCG
GTAGCCCGGGTATTGCGCAAGCTGGCCCTGGTCTGGGGCGTGCAGCCCCTTCTGGTAGGACGCACCCGGGACACTGATAG
TATGATTGCTTCAGCCATTGAAGCATCCCTGGCGGCAGACCTGATTAAACCAGGAGATCTGGTTGTCATTACCGCCGGCG
TTCCCGTGGGTGTCCATGGCACCACCAACCTGTTAAAAGTCCATACTGTTGGGGATATCCTGGTCCGCGGCCAGGGTATT
GGCACGCGGGCGGTAACCGGACGTGTGCGCATCTGCCACACCTTGAAGGATGCTTTGGAAAAGGTGGAACCCGGGGACAT
CCTGGTCACACCCTTCACCGACAAGGATTTTATACCGGCCATTGAAAAAGCGGCCGCCCTGATTACTGAGGTGGGAGGCC
TGACTTCCCATGGTGCCATTGTTGGCCTGGAATTTGGCATTCCGGTAATTGTGGGGGTAGATGCCGCCACCTCCATCCTT
ACCGATGGGGATACGGTGACGGTCGACGGACAACGCGGCCTGGTGTACCGGGGTACCGCCAGGGTGCTATGA

Protein sequence :
MRRTKIICTIGPACEQVETLMEMMRAGMNIARLNFSHGTHEEHARRIANIREAAGRVGKNIAILLDTKGPEIRLGYLEKE
PVVLKAGQRVVLTTENIKGTPERLPITYAGLPRDVAPGNTVLIADGLIELRVIGSNGHEVECEVVHGGELTSQKGVNLPG
VPVNLPAITEQDIRDIKFGIEQELDFIAASFIRSASDVLAIRRILEEHGADMDIIAKIESKEGVENLDEIIKVADGIMVA
RGDLGVGLPVEEVPLIQKAIIEKCNLAGKPVITATQMLESMIHNPRPTRAEASDVANAILDGTDAIMLSGETAAGHYPVE
AVKTMARIASRVEKALPYEEILQRRGRALARTVTDAISHATCTTAQDLGAAAIITSTETGYTAKMVSKYRPRAPIIAVTP
VARVLRKLALVWGVQPLLVGRTRDTDSMIASAIEASLAADLIKPGDLVVITAGVPVGVHGTTNLLKVHTVGDILVRGQGI
GTRAVTGRVRICHTLKDALEKVEPGDILVTPFTDKDFIPAIEKAAALITEVGGLTSHGAIVGLEFGIPVIVGVDAATSIL
TDGDTVTVDGQRGLVYRGTARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-94 50
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-94 50
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-94 50
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-94 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desku_1651 YP_004517030.1 pyruvate kinase VFG0479 Protein 1e-94 50