Gene Information

Name : Metme_0544 (Metme_0544)
Accession : YP_004511488.1
Strain : Methylomonas methanica MC09
Genome accession: NC_015572
Putative virulence/resistance : Virulence
Product : Fis family transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 586101 - 587447 bp
Length : 1347 bp
Strand : +
Note : KEGG: nhl:Nhal_0598 sigma-54 factor interaction domain-containing protein; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulato

DNA sequence : 
ATGAATATGCCCGTTACTCTTGTTGTCGACGACGAACCCGATATCAGGGAGCTGTTGGATATTACCTTAAGTCGCATGAA
TATCCGCGCCTGTTGCGTTGAAACCATTAAGGAAGCGCGGCAGCTTTTGGATAGCCAGCATTTTGATTTGTGTCTGACCG
ATATGCGTCTGCCCGACGGCGACGGCTTGAGTTTAGTCGAGTATATTCAAGAGTCCGGCTTGCAGTTGCCGGTGGCCGTG
ATTACCGCCCATGGCAGTATGGATATTGCCGTCAGCGCCATGAAGAAAGGCGCCTTCGACTTTTTGAGCAAACCCGTGGA
TTTAGCCGCTTTGCGGCAATTGGTCGGCAATGCCCTGCAGGTCTCGCCCAATCATTCCCTGGAAAAAGATCGCCGGACCC
GCGATACCTTGTTGGGCGAATCGGAGTTGATGTGCGAGATTCGCTCCAAGATTCAAAAGGTGGCGCGTAATCAGGCGCCA
ATTTATATCAGCGGCGAATCCGGTTCCGGCAAGGAGTTGGTCGCCAAATTGATCCATCAGCAAGGCCCGCGCGCCGATAA
GTCGTTTGTAGCGATCAACTGCGGAGCCATACCTCACGAGTTGATGGAAAGCGAGTTTTTCGGACATAAAAAAGGCAGTT
TCAGCGGTGCCATTGCCGATAAACAAGGCTTGTTTCAGGCGGCGGACGGCGGTACGTTGTTTCTGGACGAGGTGGCGGAC
CTGCCGTTGAGTTTACAGGTCAAGCTGCTACGAGCCATTCAGGAAAAGAAAATCCGCCCCGTGGGCGAGCAGCATGAAGT
TTCCGTGGATGTACGTTTATTGAGCGCCACCCATAAGGATTTGGCGAAAATGGTGCAGGAAGGCAGTTTTAGACAGGACT
TGTATTATCGCATTAACGTTATTGAGTTGAGTTTGCCGCCGTTACGCGTCAGAGCGGCTGATATCGTGCAAATAGCCGAA
CATTTACTGGAGCGTTTGGCGAAAGCAAACCAAGTGCCGGTGCCGCAATTTAGTAGGCAAGCGTTAATCGCTTTACAGCA
GTATAGTTTTCCGGGAAATGTCAGGGAGTTGGAGAATATCCTGGAACGCGCGTTGGCCTTGCATGAGGGCGATAAGATCG
ATGTTGACGATTTAAACTTGCAAATGACGTGTGACGAAGCCGCAAAACCGCATGGCGATTACAACGCGGAACAAATGTCG
TTGGAAAATTATTTGGAGGATGTCGAGAAAAAAGCCCTGACGGCTGCCTTGGAAGAAAATCGTTGGAATAAAACCGCCGC
CGCCAAACAATTGGGCATGACATTCAGATCTTTTCGTTATCGATTGAAAAAACTGGGGCTGGAATAA

Protein sequence : 
MNMPVTLVVDDEPDIRELLDITLSRMNIRACCVETIKEARQLLDSQHFDLCLTDMRLPDGDGLSLVEYIQESGLQLPVAV
ITAHGSMDIAVSAMKKGAFDFLSKPVDLAALRQLVGNALQVSPNHSLEKDRRTRDTLLGESELMCEIRSKIQKVARNQAP
IYISGESGSGKELVAKLIHQQGPRADKSFVAINCGAIPHELMESEFFGHKKGSFSGAIADKQGLFQAADGGTLFLDEVAD
LPLSLQVKLLRAIQEKKIRPVGEQHEVSVDVRLLSATHKDLAKMVQEGSFRQDLYYRINVIELSLPPLRVRAADIVQIAE
HLLERLAKANQVPVPQFSRQALIALQQYSFPGNVRELENILERALALHEGDKIDVDDLNLQMTCDEAAKPHGDYNAEQMS
LENYLEDVEKKALTAALEENRWNKTAAAKQLGMTFRSFRYRLKKLGLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 1e-104 49
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 1e-104 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Metme_0544 YP_004511488.1 Fis family transcriptional regulator BAC0467 Protein 2e-71 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Metme_0544 YP_004511488.1 Fis family transcriptional regulator VFG1214 Protein 1e-133 61
Metme_0544 YP_004511488.1 Fis family transcriptional regulator VFG0116 Protein 3e-65 42
Metme_0544 YP_004511488.1 Fis family transcriptional regulator VFG1249 Protein 5e-66 41