Gene Information

Name : Metme_0404 (Metme_0404)
Accession : YP_004511349.1
Strain : Methylomonas methanica MC09
Genome accession: NC_015572
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 428817 - 430403 bp
Length : 1587 bp
Strand : +
Note : PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; NAD+ synthase; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; HAMAP: GMP synthase [glutamine-hydrolyzing]; KEGG: tgr:Tgr7_1036 GMP synthase

DNA sequence :
GTGACACAAGCCCACGCCAATATCCATTCCGACAAAATTCTGATTCTCGACTTCGGCTCGCAATACACGCAACTGATTGC
CCGCCGCATCCGCGAAATTGGTGTCTATTGCGAAATATACTCTTGCGACAGTTCCGCGGACGAAGTCAAAAATTTCGGCG
CAAAAGGCATTATTCTGTCCGGCGGCCCGGAAACGGTTACCAGCAACGATACCCCCCGAGCGCCCGCTTGCGTCTTCGAA
CTCGGCATTCCGGTACTGGGCATTTGTTACGGCATGCAGACCATGGCCGAGCAATTGGGCGGCAGGGTCGAATCCTCCGA
CCACCGAGAATTTGGCTATGCGCAGATTCGCGCTCGAGGCCATTCCAAACTGTTACTGAATATAGAAGACCACGCATCGC
CGGAAGGTTACGGTTTGCTGGATGTCTGGATGAGTCACGGCGACCGCGTCGTCGAATTGCCGGCAGGCTTCAAATTGATC
GCCAGCTCCGACGGTGCGCCGATTGCCGGCATCGCCGACGAAGATAGACACTTTTACGCGCTGCAATTTCATCCGGAAGT
CACCCACACCAAGCAAGGCGGCCGTATTCTGGGTCGTTTCGTATTGGAAATTTGCGGTTGCCAGGCACTTTGGAATGCCA
ACAACATTATCGAAGACAGCATCGCTGCTGTCCGCGAAAAAGTCGGATCCGACCAAGTGATTCTGGGCTTGTCCGGCGGC
GTTGATTCATCGGTGGTCGCGGCCCTGCTGCACAAGGCTATAGGCGAACAACTGACCTGCGTGTTCGTAGACACCGGCTT
GCTGCGCCTGCACGAAGGAGACCAAGTCATGGCGATGTTTGCCCAGCATATGGGCATCAAGGTCATCCGCGTGGATGCGG
AACAGCGTTATCTGGACGCATTAGCCGGCGTCAACGACCCGGAAGCCAAACGTAAAATCATCGGCGGCCTGTTTGTGGAA
ATTTTCGACGAAGAAGCCGGCAAGCTCACCGATGCCAAATGGCTGGCGCAGGGCACTATCTACCCGGACGTGATCGAATC
GGCTGGCGCTAAAAGCGGCAAGGCCCATCTAATCAAATCGCATCACAACGTGGGTGGATTGCCGGAAAACATGACCTTGA
AACTGGTCGAGCCCCTGCGCGAGCTGTTCAAGGACGAAGTGCGCAAACTCGGTCTGGAACTAGGCTTGCCCGCAGACATG
ATCCATCGCCACCCTTTCCCCGGCCCCGGCCTAGGCGTACGCATTCTGGGCGAAGTTAAAAAGCAATATGCCGATTTGTT
GCGTCAAGCGGACGCCATCTTCATCGGAGAACTCTATCGCCACGACCTTTACCACAAAGTCAGCCAAGCCTTCGCGGTAT
TCCTGCCGGTCAAATCCGTCGGCGTGATGGGAGACGGCCGCAAATACGATTACGTCATCGCCATCCGCGCCGTGGAAACC
ATAGACTTCATGACCGCGCGTTGGGCGCATCTACCTTATGATTTTCTGGATTTGATTTCGCGGCGGATAATCAACGAAGT
GAACGGCATTTCGCGCGTCACTTACGACATATCCGGCAAGCCTCCGGCTACGATTGAGTGGGAGTAA

Protein sequence :
MTQAHANIHSDKILILDFGSQYTQLIARRIREIGVYCEIYSCDSSADEVKNFGAKGIILSGGPETVTSNDTPRAPACVFE
LGIPVLGICYGMQTMAEQLGGRVESSDHREFGYAQIRARGHSKLLLNIEDHASPEGYGLLDVWMSHGDRVVELPAGFKLI
ASSDGAPIAGIADEDRHFYALQFHPEVTHTKQGGRILGRFVLEICGCQALWNANNIIEDSIAAVREKVGSDQVILGLSGG
VDSSVVAALLHKAIGEQLTCVFVDTGLLRLHEGDQVMAMFAQHMGIKVIRVDAEQRYLDALAGVNDPEAKRKIIGGLFVE
IFDEEAGKLTDAKWLAQGTIYPDVIESAGAKSGKAHLIKSHHNVGGLPENMTLKLVEPLRELFKDEVRKLGLELGLPADM
IHRHPFPGPGLGVRILGEVKKQYADLLRQADAIFIGELYRHDLYHKVSQAFAVFLPVKSVGVMGDGRKYDYVIAIRAVET
IDFMTARWAHLPYDFLDLISRRIINEVNGISRVTYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-129 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-128 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-129 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-114 48