Gene Information

Name : Metme_3340 (Metme_3340)
Accession : YP_004514210.1
Strain : Methylomonas methanica MC09
Genome accession: NC_015572
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3678895 - 3680763 bp
Length : 1869 bp
Strand : +
Note : TIGRFAM: Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; KEGG: mca:MCA2710 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC

DNA sequence :
ATGAGCGCTGTCCGCAATGAAATTACTACCGATACCGGCAGTAGCATAAGAATCGATTCCTACCCCGCCTCGGAAAAAGT
CTACATTCCCGGCAGCCGGCCCGATATTCAAGTACCGATGCGTCAAATTAACCTGTCGGACACCCCCGCCACTTTCGGCG
CCGAAAAAAACCCGCCGATTTTCGTCTACGACACCTCCGGTGTGTACACCGACCCGAATGTCGATGTCAATCTGCATAAA
GGCCTGAGTTCGATACGCGGCGCCTGGATAGATGAGCGCGGCGACACCGAATTACTGAGCGGCCCCACGTCCAAATACGG
CCATGAACGCTTGCACGACCCCAAAACAGCCCATCTGCGTTTCGAACTGACCCGCAATCCGCGTCGCGCCAAGGCCGGCC
ATAACGTCTCGCAAATGCATTATGCCCGCAAAGGCATCATCACCCCGGAAATGGAATATATCGCCATTCGCGAAAACCAA
AATCTGGAAGTCATGCGCGACCGTTATAAAGGCCAACACCCTGGTTTTTCCTACGGCGCCAACATTCAAACCATGATCAC
ACCGGAATTCGTCCGCTCGGAAGTCGCCCGCGGCCGCGCCATCATCCCGGCCAACATCAACCACCCCGAACTGGAACCAA
TGATCATCGGCCGCAACTTCCTGGTCAAGATCAACGGCAACCTGGGTAACTCGGCGGTAACTTCTTCCATTGAGGAAGAA
GTGGAAAAGATGCTGTGGGGCATCCGCTGGGGCGCCGACACCATCATGGATTTATCGACCGGTAAAAATATCCACGAAAC
CCGCGAATGGATCTTGCGCAATTCGCCCGTACCGATCGGCACGGTGCCGATATACCAAGCCCTGGAAAAAGTCGACGGCA
GAGCCGAAGAACTGACCTGGGAAATCTTCCGCGACACCCTGATCGAACAAGCCGAGCAAGGCGTGGATTATTTCACCATT
CACGCCGGCGTGCGCCTGCACCACGTGCCGCTGACCGCCAAGCGCCTGACCGGCATTGTCTCGCGCGGCGGTTCCATCAT
GGCCAAATGGTGTCTGGCACATCACACCGAGAGCTTCCTCTACACAAACTTCGAGGAAATCTGCGAGATCATGAAAGCCT
ACGACGTGTCGTTCTCGTTAGGCGACGGACTGCGGCCCGGTTCGATTTACGACGCCAACGACGAAGCCCAGTTCGGCGAA
CTGGAAACCCTGGGCGAGCTGACCCAAATCGCCTGGAAACACGACGTGCAAACCATGATCGAAGGCCCCGGCCACGTGCC
GCTGCAAATGATCAAGGTCAACATGGAAAAACAATTGGAAGACTGCTTCGAAGCACCTTTTTATACCTTGGGTCCGCTGA
CCACCGACATTGCCCCCGGCTACGACCACATCACGTCCGCGATCGGCGCCGCCAACATCGGCTGGTACGGCTGTGCGATG
CTGTGCTATGTCACCCAGAAAGAACACTTGGGCCTGCCCAACAAACAGGACGTGCGCGAAGGCATCGTCACCTACAAAAT
CGCCGCCCACGCGGCCGACTTGGCTAAAGGTCATCCAGGCGCGCAAATCCGCGACAACGCCATGTCCAAGGCCCGCTTCG
AATTTCGCTGGGAAGACCAGTTCAATCTGGCGCTGGACCCTGAAAAAGCCCGCTCTTTCCATGACGAGACCCTGCCTAAG
GATTCGGCCAAGGTTGCCCATTTCTGTTCGATGTGCGGCCCGCATTTCTGTTCGATGAAAATCAGCCAGGACGTGCGCGA
TTACGCGGCGGAAAAAGGCTTACAGGAAGAAGAAGCGCTTAGACAAGGTATGGTTGAAAAGTCAGAGCAATTTTTGAAGG
AAGGCGCGGCGATCTATCACGAAGTGTAA

Protein sequence :
MSAVRNEITTDTGSSIRIDSYPASEKVYIPGSRPDIQVPMRQINLSDTPATFGAEKNPPIFVYDTSGVYTDPNVDVNLHK
GLSSIRGAWIDERGDTELLSGPTSKYGHERLHDPKTAHLRFELTRNPRRAKAGHNVSQMHYARKGIITPEMEYIAIRENQ
NLEVMRDRYKGQHPGFSYGANIQTMITPEFVRSEVARGRAIIPANINHPELEPMIIGRNFLVKINGNLGNSAVTSSIEEE
VEKMLWGIRWGADTIMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVDGRAEELTWEIFRDTLIEQAEQGVDYFTI
HAGVRLHHVPLTAKRLTGIVSRGGSIMAKWCLAHHTESFLYTNFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFGE
LETLGELTQIAWKHDVQTMIEGPGHVPLQMIKVNMEKQLEDCFEAPFYTLGPLTTDIAPGYDHITSAIGAANIGWYGCAM
LCYVTQKEHLGLPNKQDVREGIVTYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPEKARSFHDETLPK
DSAKVAHFCSMCGPHFCSMKISQDVRDYAAEKGLQEEEALRQGMVEKSEQFLKEGAAIYHEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 77
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 77
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 73