Gene Information

Name : Metme_3280 (Metme_3280)
Accession : YP_004514151.1
Strain : Methylomonas methanica MC09
Genome accession: NC_015572
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 3615876 - 3617372 bp
Length : 1497 bp
Strand : -
Note : PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; TIGRFAM: Lysyl-tRNA synthetase, class II; HAMAP: Lysyl-tRNA synthetase; KEGG: ilo:IL0822 lysyl-tRNA synthetase

DNA sequence :
ATGTCAGAACTCGAACAAGACGAACAAGAACAGATCAGGCAACGCCGCGAAAAACTTAACGCTATCCGCGAGGAGGGTAT
AGCATTTCCGACCGACTTTCGCCGCAACGTGGTGGCGGGCGAGTTAATCGCCGAATACGGCGAGAAACCGGAAGAGGAAT
TAACCGCCGAGCCGATTCGGGTGAAAATTGCCGGCCGGATGATGACGCGCCGTATCATGGGCAAGGCCAGTTTTTGCCAT
TTGCAGGATATGTCTGGGCAGATTCAGGTCTACGTGGCCCGCGACAATCTCCCGGAAGGCGTGTACAACGAGCAGTTCAA
AAAATGGGATATTGGCGATATCGTCGGCGCCGAGGGCGTATTGTTTAAGACCAAAACGGGCGAACTGAGCGTCAAGCTCG
ACAGCATTCGTTTGCTGACCAAAGCGCTGCGGCCGCTGCCGGAAAAATTCCACGGTATCGCCGATCAGGAGATCAAGTAC
CGCCAGCGTTATCTGGATCTGATCATGAGCGACGAGGCGCGCAAAACCTTTTTGATGCGTTCCAAAATCGTCAATTATAT
CCGGGATTTTTTGACCCATCGCGACTTTCTGGAAGTGGAAACCCCGATGATGCAGGTGATTCCGGGCGGGGCCACCGCAC
GGCCGTTTACCACCTTTCACAATGCGCTGGATATGGACTTGTATCTGCGCATCGCGCCTGAGCTGTATCTGAAAAGGCTG
GTGGTGGGCGGTTTCGAACGGGTGTTCGAGATTAACCGCAACTTCCGCAACGAAGGTTTGTCGACCCGACATAATCCTGA
ATTCACCATGTTGGAGTTTTATCAAGCTTACGCCGAGTACGGCGATTTGATGGATTTGACTGAAGCCATGCTGCGCGGCA
TTGCCGAAGATATCGTCGGCCGAACGATCATCGAATATCAAGGCGAGCACTACGATTTCGGTAAACCTTTTGTGCGGATG
ACGGTGCTGGAATCGATTCTGCATTTCAACCCGGATTTGACGTTGGAGGATTTGCAAACCCGTGAAGCGGCGGCAAAAGT
GGCGGAAAATCTGAAAATCCCGGTCAAGGACAGTTACGGTTTAGGCAAAATTCAGATTGAGATTTTCGAAAAAACCGTCG
AACATCGCTTGATGAATCCGACTTTTATCACCGCTTATCCGGTGGAAGTGTCCCCTCTGGCTCGTCGTAACGATGACGAC
CCGCATGTCACCGACCGCTTCGAGTTTTTCGTCGGCGGCCGGGAAATCGCCAACGGTTTTACCGAGCTGAACGACGCCGA
GGATCAGGCCGAACGATTCCAGAAACAAGTGCAGGAAAAAGAAGCCGGCGATAATGAAGCCATGCATTTCGATGCCGATT
ACATCACGGCACTGGAGCACGGCATGCCGCCGACGGCCGGGGAGGGTATCGGTATCGATCGGTTGGTGATGTTGTTTACC
AACGCCCCGAGTATTCGCGACGTGTTGTTGTTCCCGCACATGCGGCCGAAAAATTAA

Protein sequence :
MSELEQDEQEQIRQRREKLNAIREEGIAFPTDFRRNVVAGELIAEYGEKPEEELTAEPIRVKIAGRMMTRRIMGKASFCH
LQDMSGQIQVYVARDNLPEGVYNEQFKKWDIGDIVGAEGVLFKTKTGELSVKLDSIRLLTKALRPLPEKFHGIADQEIKY
RQRYLDLIMSDEARKTFLMRSKIVNYIRDFLTHRDFLEVETPMMQVIPGGATARPFTTFHNALDMDLYLRIAPELYLKRL
VVGGFERVFEINRNFRNEGLSTRHNPEFTMLEFYQAYAEYGDLMDLTEAMLRGIAEDIVGRTIIEYQGEHYDFGKPFVRM
TVLESILHFNPDLTLEDLQTREAAAKVAENLKIPVKDSYGLGKIQIEIFEKTVEHRLMNPTFITAYPVEVSPLARRNDDD
PHVTDRFEFFVGGREIANGFTELNDAEDQAERFQKQVQEKEAGDNEAMHFDADYITALEHGMPPTAGEGIGIDRLVMLFT
NAPSIRDVLLFPHMRPKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-143 60
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-85 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Metme_3280 YP_004514151.1 lysyl-tRNA synthetase VFG1668 Protein 3e-143 60