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Name : Metme_1967 (Metme_1967) Accession : YP_004512879.1 Strain : Methylomonas methanica MC09 Genome accession: NC_015572 Putative virulence/resistance : Unknown Product : HsdR family type I site-specific deoxyribonuclease Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 2159865 - 2162999 bp Length : 3135 bp Strand : + Note : TIGRFAM: Restriction endonuclease, type I, EcoRI, R subunit; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; KEGG: app:CAP2UW1_1871 type I site- DNA sequence : ATGACCGAAGACCAACTGGAACAGGAAGCACTCGGCTGGCTGGCCGAGGTTGGATACTCTACGCTTTACGGGCCAGACCT GGCGCCGGATGGCGACAACCCGGAGCGCGACAATTACCTGCAAGTGGTGCTGGTCGAAAGATTACGTTCGGCGATTGCCC GCTTAAACCCGTCTATTCCACTGGCGGCGCGGGAAGATGCCTTGCAGCAGATATTGAATCTGGAAGTGCCGGGATTGTTG GCAGCCAATCGCCACTTTCATCGTCTGTTAGTCAATGGCGTGCCGGTGGAGTATCAAAAGGACGGTGATACGCGGGGCGA TAGGGTGCGCTTGATCGAGTTTGCCGAGCCGTCCAGCAATGAATGGTTAGCGATCAATCAATTTGCCATCAAGGGGCCGA AACATTCACGTCGGCCGGACATCATCCTATTCATCAATGGCCTGCCGTTGGTGTTGCTGGAGCTGAAAAATCCGGCTGAT GAGAACGCTGACATCTGGAAAGCTTTCGGTCAGATTCAAACCTATAAAGAACAAATCCCGGATGTATTCCAGTACAACGA AGTGTTGGTGGTTTCTGACGGTAGCGAGGCGCGGCTGGGTTCGTTATCCAGCGATGCCGAACGCTTTATGCAGTGGCGCA CCATCGACGGCATCACACTGGACCCGTTAGGCCAATTCAACGAACTGGAAACGCTGATACACGGTTTGTTGAACCCGGCG ACTTTGCTCGATTACTTGCGCTTTTTCGTGCTGTTCGAGGATGACGGCGGCCTAGTCAAAAAGGTTGCCGGTTACCATCA ATACCATGCGGTACGCGCGGCGATTCAACAAGTGGTGACCGCTTCCCGCCCTGATGGCAACCATAAGGGCGGCGTGGTCT GGCACACGCAAGGCAGTGGCAAAAGTATCACCATGACCTGTTTTGCCGCTCGCGTGATGCAGGAAACGGCGATGGAGAAT CCGACCATTGTGGTGATCACCGACCGCAACGACCTGGATGGGCAATTGTTTGGGGTATTCTCGTTGGGGCAGGATTTACT CCGCGAACAACCGGTGCAAGCTGAAACTCGGCAGGACTTGCGGGCCAAGTTGGACAATCGACCATCCGGCGGCATCGTTT TCGCCACCATTCAGAAATTTATGCCGGGTGCCGACGAAGACAGTTTCCCGGTGCTATCCGATCGCAGCAATATCGTGGTG ATTGCCGATGAAGCACATCGCACTCAGTATGGTTTTGAAGCCAAGCTCAAAACCGTCAAAACCCAACAAACCGCTGCCAA CGAGGGCAGGGTGGACATGGCCGCCGAATACCGAGGCATGTATCAAGTTGGTTATGCCCAGCATTTACGCGATGCTTTGC CAAATGCCACCTTTGTCGCTTTTACCGGTACTCCGGTGTCGCTGGAAGACCGCGATACCCGCGCGGTGTTTGGCGAATAT ATTCATGTCTACGACATGCAGCAGGCCAAAGAAGACGGCGCGACAGTGGCAATTTACTTTGAATCGCGACTGGCCAAGTT GGCACTGAAGCCGGAGCAATTGCCACAGATCGATGATGAGGTTGATGAACTGGCCGAGGATGAAGAGGAAGATCAGCAGG CTAAGTTGAAAAGTCGTTGGGCGGCCTTGGAAAAAGTGGTCGGTGCCGAACCGCGTATCGCCAGCGTGGCTGCGGATTTG GTGGCCCACTTCGAAGAACGTAATAAGGCACAAGATGGCAAGGCCATGGTGGTGGCGATGAGCCGGGAAATTTGTGTGCA TCTGTATAACGAGATCATCAAGCTACGCCCTGACTGGCACAGCGACGATCCCGAGCAAGGCGCGATCAAAATCGTCATGA CCGGCTCCGCCAGTGACAAAGCCTTGCTGCGGCCGCATATCTACAGCAAACAACAGAAAAAGCGCCTGGAAAAGCGCTTT AAAGACCCGGCCGATCCGTTGCGATTGGTCATCGTCCGTGACATGTGGCTTACCGGCTTCGACGCGCCGTGTGTGCATAC GCTGTATGTCGATAAACCGATGAAGGGCCACAACCTGATGCAAGCCATCGCCCGCGTCAACCGGGTATTTAAAGATAAGC AAGGCGGCCTGGTGGTGGATTACATCGGCATCGCCAACGAATTAAAGTCTGCTTTGAAGGACTACACCGCCAGCCAGGGC CGTGGCCGACCCACCGTCGATGCGGCCGAAGCCTATGCCGTGCTGGAGGAAAAGCTCGATATTCTGCGGGGCATACTGCA CGGCTATGACTACAGTGACTTTTTAACCACAGGCCATAAACGACTGGCCGGCGCAGCCAACCATGTGCTGGGTCAGAAGG ACGGCAAAAAGCGTTTTGCCGATACCTCGCTGGCGATGAGCAAGGCCTTTACCCTGTGTTGCACGCTGGACGAAGCCAAG GCGGTACGGGAGGAAATGGCGTTTTTTCAGGCGGTGAAAGTCATTCTCACCAAGCCCGACATCAGCCGGAAAAAACGCAG CGACGAGGAACGTGATCTGGCGATTCGTCAAATCATCAATTCCGCCGTGGTCTCGGAAGATGTGGTGGACATCTTCGAAG CCGTTGGTCTGGACAAGCCCAACATCGGTATCCTTGATGAAGCCTTTCTGGCCGACGTGCGTAACCTGCCGGAACGCAAT CTGGCCGTGGAGTTGCTGGAGCGGCTACTGGAAGGTGAAATCAAATCTCGCTTTGCCGGCAACGTGGTGCAGGAAAAGAA GTTCTCCGAGCTGTTGACCAATGTCATCAAGCGTTATCAAAACCGGGCTATCGAAACAGCCCAGGTGATTGAAGAGCTGA TCCAGATGGCTAAGAAGTTTAGAGAAGCTGCCGGACGCGGGGAATCGTTGGGGTTGAGCGAAGATGAAATTCGCTTCTAC GATGCATTGGCCGATAATGAATCAGCCGTCCGCGAACTGAGCGATGACACCCTGAAGCTTATCGCCCATGAGCTTACAGA GAACCTACGCCAGAACATTACGGTGGACTGGTCGCAACGGGAAAGCGTCAGGGCCAAGTTACGCTTGATGGTGAAACGTA TCCTTCGTAAGTACAAGTATCCGCCAGACCAACAGGAGGCGGCGATTGAGCTGGTTTTGCAGCAGGCACAGGCGTTAGGT GACGCATGGATTTAG Protein sequence : MTEDQLEQEALGWLAEVGYSTLYGPDLAPDGDNPERDNYLQVVLVERLRSAIARLNPSIPLAAREDALQQILNLEVPGLL AANRHFHRLLVNGVPVEYQKDGDTRGDRVRLIEFAEPSSNEWLAINQFAIKGPKHSRRPDIILFINGLPLVLLELKNPAD ENADIWKAFGQIQTYKEQIPDVFQYNEVLVVSDGSEARLGSLSSDAERFMQWRTIDGITLDPLGQFNELETLIHGLLNPA TLLDYLRFFVLFEDDGGLVKKVAGYHQYHAVRAAIQQVVTASRPDGNHKGGVVWHTQGSGKSITMTCFAARVMQETAMEN PTIVVITDRNDLDGQLFGVFSLGQDLLREQPVQAETRQDLRAKLDNRPSGGIVFATIQKFMPGADEDSFPVLSDRSNIVV IADEAHRTQYGFEAKLKTVKTQQTAANEGRVDMAAEYRGMYQVGYAQHLRDALPNATFVAFTGTPVSLEDRDTRAVFGEY IHVYDMQQAKEDGATVAIYFESRLAKLALKPEQLPQIDDEVDELAEDEEEDQQAKLKSRWAALEKVVGAEPRIASVAADL VAHFEERNKAQDGKAMVVAMSREICVHLYNEIIKLRPDWHSDDPEQGAIKIVMTGSASDKALLRPHIYSKQQKKRLEKRF KDPADPLRLVIVRDMWLTGFDAPCVHTLYVDKPMKGHNLMQAIARVNRVFKDKQGGLVVDYIGIANELKSALKDYTASQG RGRPTVDAAEAYAVLEEKLDILRGILHGYDYSDFLTTGHKRLAGAANHVLGQKDGKKRFADTSLAMSKAFTLCCTLDEAK AVREEMAFFQAVKVILTKPDISRKKRSDEERDLAIRQIINSAVVSEDVVDIFEAVGLDKPNIGILDEAFLADVRNLPERN LAVELLERLLEGEIKSRFAGNVVQEKKFSELLTNVIKRYQNRAIETAQVIEELIQMAKKFREAAGRGESLGLSEDEIRFY DALADNESAVRELSDDTLKLIAHELTENLRQNITVDWSQRESVRAKLRLMVKRILRKYKYPPDQQEAAIELVLQQAQALG DAWI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 56 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 48 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 47 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 47 |
