Gene Information

Name : Metme_1268 (Metme_1268)
Accession : YP_004512194.1
Strain : Methylomonas methanica MC09
Genome accession: NC_015572
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1375821 - 1377092 bp
Length : 1272 bp
Strand : -
Note : KEGG: prw:PsycPRwf_0249 UDP-glucose/GDP-mannose dehydrogenase; TIGRFAM: Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-

DNA sequence :
ATGCTAAATAACATCAAAATCGGCATGATAGGCTTGGGCTATGTTGGCTTGCCCCTGGCCGTGGAGTTTGGGCAAAAATA
TCCGACTGTGGGTTTTGACATTAATCATCACCGCATCACCGAACTGCAATCCGGTAATGACCATACCCTGGAGGTCAGTT
CGGCGGAACTCGCGGAAGCCACCCAGCTGACATACAGTTCTCACATGCAGGACATTGCCGATTGTACTGTTTATATCGTC
ACGGTACCCACGCCAATTAATGAGCACAAGCAGCCGGATTTAACCCCGCTGCAAAAAGCCAGCGACCTGCTGGGACAAGT
CATTAAAGCCGACGATATTGTCATTTACGAATCCACCGTTTACCCCGGCGCCACTGAAGAAGTGTGCGTACCTATCCTGG
AAAAAGTCTCCGGATTGAAATTCAACCGGGATTTTTATGTGGGTTACAGCCCCGAGCGGATCAACCCGGGCGATAAACAA
CATCGGGTAACGAATATCTTAAAAGTCACATCCGGTTCAACCCCGGAGATTGCCGAAAAAGTCGACCAACTTTATAAAAG
CATCATCACGGCCGGGACGCACAAAGCCAGCAGCATCAAGGTAGCCGAAGCCGCTAAAGTCATCGAAAACACCCAGCGCG
ACGTCAATATCGCCTTGATCAACGAACTGGCACTGATTTTTAACAAATTAAGCATCGATACCGAGGAAGTGTTGCTGGCA
GCCGGCACCAAATGGAATTTTTTACCGTTTCGGCCCGGCTTGGTCGGCGGCCACTGTATCGGCGTCGACCCCTATTATCT
GACCCATAAAGCGCAAGCCATCGGCTATAATCCGGAAGTGATTCTATCCGGCCGCCGCATCAATGACAGCATGGGCGCGT
ATGTTGTTTCGCAACTGATCAAGTTGATGCTGAAAAAGCGCATCCAGGTGCAAGACGCCCGAGTATTGATCATGGGCCTG
ACTTTTAAGGAAAACTGTCCGGATATCCGCAACACCCGGGTAGTGGATATTGTGGCGGAACTGAAAACCTACGGTATCAC
CGTGGACGTTTACGACCCTTGGGTCAACGGCGACGAGACTTTCGAAGAATATGGCATACGCCCCATCGTACAACCTAGCA
GAGGTAAATACGATGCCATGATATTGGCCGTCGCGCACGAGGAATTCAAGGAAATGCCGATCAACGACATCCGCGCACTG
GGCAAGGAGCAGTCCATCATTTACGACTTAAAATACTTATTCCCGGCTGAACTAACCGACGCGAGACTGTAA

Protein sequence :
MLNNIKIGMIGLGYVGLPLAVEFGQKYPTVGFDINHHRITELQSGNDHTLEVSSAELAEATQLTYSSHMQDIADCTVYIV
TVPTPINEHKQPDLTPLQKASDLLGQVIKADDIVIYESTVYPGATEEVCVPILEKVSGLKFNRDFYVGYSPERINPGDKQ
HRVTNILKVTSGSTPEIAEKVDQLYKSIITAGTHKASSIKVAEAAKVIENTQRDVNIALINELALIFNKLSIDTEEVLLA
AGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAIGYNPEVILSGRRINDSMGAYVVSQLIKLMLKKRIQVQDARVLIMGL
TFKENCPDIRNTRVVDIVAELKTYGITVDVYDPWVNGDETFEEYGIRPIVQPSRGKYDAMILAVAHEEFKEMPINDIRAL
GKEQSIIYDLKYLFPAELTDARL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-137 65
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-137 65
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 9e-109 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Metme_1268 YP_004512194.1 nucleotide sugar dehydrogenase VFG0431 Protein 4e-138 65