Gene Information

Name : PGTDC60_2201 (PGTDC60_2201)
Accession : YP_004510904.1
Strain : Porphyromonas gingivalis TDC60
Genome accession: NC_015571
Putative virulence/resistance : Virulence
Product : UDP-glucose-6 dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2271972 - 2273237 bp
Length : 1266 bp
Strand : -
Note : similar to RefSeq{20100916}, gi|34540979|ref|NP_905458.1| UDP-glucose-6 dehydrogenase, putative [Porphyromonas gingivalis W83]|, percent identity 99.8 in 421 aa, BLASTP E(): 0

DNA sequence :
ATGAATAACATTAGGATTGCTATCATCGGTTTGGGATATGTGGGTCTCCCTTTAGCTCGTCTGTTTTCCACAAAATTTCC
GACAATCGGCTTCGACATCAACCCGAACCGTGTAGAAGAACTAATGTCAGGATATGACAGCACGGGGGAAATTGGAAATG
AATTATTACAGGAAGCCTTGCAAAAGGGGTTACTTTGTACAACAAAAATTGAAGAGATTAGGGATTGTAACTTCTATATC
GTGACAGTTCCTACCCCTATAGATCACAATCACACCCCGGACTTACGGCCACTTTTGGCAGCCAGCGAAACAATCGGAAA
GGTAATCGGCCAAGGAGATGTGGTGGTGTACGAAAGTACGGTGTATCCCGGTGTAACAGAAGACGAATGTATTCCGATTA
TCGAGAAAGTTTCGGGTCTCAAATACAATGTGGACTTCTTTGCCGGATACAGTCCCGAACGAATCAATCCGGGAGATAAA
GTTCACACAGTAGAGAATATAAAAAAAGTGACATCCGGTTCTACTCCGGAAATAGCCGACTATGTGGATAGAATGTATAA
TACCGTGTTGGTCAATGGCACACACAAAGCATCTTCCATAAAAGTTGCAGAGGCTTCAAAAATCATAGAAAATGCCCAAC
GAGATGTAAACATTGCATTTATGAACGAAATCGCGAAGATTTTCAATGCAATGGACATTGATACGCGCGAAGTATTGGAG
GCTGCAGCTACAAAATGGAACTTCCTACCTTTTCAGCCGGGCTTGGTCGGTGGGCATTGTATAGGGGTAGACCCCTATTA
CCTTATTCAGCGAGCACAGGTATATGGAGTTTATCCTCGGGTATTGATGTCTGCGAGAAGGCTGAATGACAGCATGGGCT
CCTATATAGCCTCGCAAACCATCAAGCAAATGAATAAAGCAGGCATCATGGTGAAAGATGCACGAATTCTGATTTTAGGA
TTTACATTCAAAGAGAATTGTCCGGATATCCGTAATACCAAAGTGATAGACACGTACAGCACCCTGCAAGAATACACGAA
AAATATTATAGTACACGATCCTTGGGCAAATCCTTCTATCGCTGAGCAAGTATATGGAATAAAGATTCACAATGAATTCC
CTAAAGGAAAATTCGATGCCATTATTATTGCTGTAGCGCATAGAGATTTTTCGAATATCGATCTCGAAAAATCATCCACA
GCCAACACCATTATCTACGATGTGAAGGGCATTCTACCCCAAGGGAAAAAGTGTCACAAACTGTAG

Protein sequence :
MNNIRIAIIGLGYVGLPLARLFSTKFPTIGFDINPNRVEELMSGYDSTGEIGNELLQEALQKGLLCTTKIEEIRDCNFYI
VTVPTPIDHNHTPDLRPLLAASETIGKVIGQGDVVVYESTVYPGVTEDECIPIIEKVSGLKYNVDFFAGYSPERINPGDK
VHTVENIKKVTSGSTPEIADYVDRMYNTVLVNGTHKASSIKVAEASKIIENAQRDVNIAFMNEIAKIFNAMDIDTREVLE
AAATKWNFLPFQPGLVGGHCIGVDPYYLIQRAQVYGVYPRVLMSARRLNDSMGSYIASQTIKQMNKAGIMVKDARILILG
FTFKENCPDIRNTKVIDTYSTLQEYTKNIIVHDPWANPSIAEQVYGIKIHNEFPKGKFDAIIIAVAHRDFSNIDLEKSST
ANTIIYDVKGILPQGKKCHKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-107 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-107 54
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-102 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PGTDC60_2201 YP_004510904.1 UDP-glucose-6 dehydrogenase VFG0431 Protein 1e-107 54