Gene Information

Name : clpC (PGTDC60_0010)
Accession : YP_004508747.1
Strain : Porphyromonas gingivalis TDC60
Genome accession: NC_015571
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 7402 - 9981 bp
Length : 2580 bp
Strand : +
Note : similar to RefSeq{20100916}, gi|34539890|ref|NP_904369.1| ATP-dependent Clp protease, ATP-binding subunit ClpC [Porphyromonas gingivalis W83]|, percent identity 98.7 in 859 aa, BLASTP E(): 0

DNA sequence :
ATGGCATACGACTTTACACAAACATTCCGCAACAGCCTGGAGTACAGCTATCAGGAAGCAACCCGTCTCGGCGTCGTAGC
CGTGACGCAGGATATGCTCGTACTCGGTATCATTCGCGACGGAGACAATGGCGCGATCGACATCATGCGGCACTATGGGA
TCAACTTGTACGAACTCAAACGGTTGATCGAGTTGGAAGCCATCGCCGAGAGTTTGCCTGCTTCGCCTGAGGGATCGCCC
ATCTTCACCCCTTCGGCTCGGGAGGCTATCAATGATGCCACAGACATCTGTGCCGACATGGAGGACGAGGCCGTCAGCCC
GGTCCATCTGTTGCTGAGTATCCTCAACTCGACACAGGAGAGCTTAGTACAAAAGATATTTATGAAACAAGGTATAAAAT
ACGACACCATCCTGTCGGATTACTTCGGACAGCGCAACCCCTCCGAAGGGAAGTCTCCCTCCGAAATGGAGATCCTCGAC
GGGTACCAAGACAACGACTTCGACGACGAAGAGGACGAATCCTCTCCGCCTTCCGGGAATGGCGGGGCAGGCAGAGGCTC
CGGCGACGCCCCCGAACAGAATACCGGCGGAGGCGATACTACCACCACGACACGGAGTGGAGGCGACACGCCTGCACTGG
ACACCTTCGGCACCGACATCACCGCCATGGCAGCAGCAGGCAAGCTCGACCCGGTAGTGGGTCGGGAGCAGGAGATCGAA
AGGGTGATACAGATACTCAGCCGGCGCAAAAAGAACAATCCGGTGCTCATCGGCGAACCCGGTGTGGGCAAGAGTGCCAT
CGTGGAAGGACTGGCCGAACGCATCGTGAACAGGAAGGTGAGCCGTATTCTTTTCGACAAGCGGATCATCAGCCTCGATT
TGGCTCAGATGGTAGCCGGCACCAAATATCGCGGACAGTTCGAAGAGCGGTTGAAAGCCGTGCTCGATGAGCTGAAGAAG
AATCCGCAGATCATCTTCTTCATCGACGAGATACATACCATCGTGGGAGCAGGCTCTGCAGCCGGATCGATGGATACGGC
CAATATGCTCAAACCCGCTCTTGCCCGTGGACAGATACAGTGCATCGGAGCCACTACGCTGGATGAGTATCGTAAGAACA
TAGAAAAGGACGGAGCACTCGAACGCCGCTTCCAGAAGGTGCCGATAGCCCCCTCGACTGCAGAAGAAACGCTGACCATC
CTGCAAAACATCAAAGAGAAATACGAGGACTATCACGGTGTACGCTATACGGACGAAGCGATCAAAGCGGCAGTGGAACT
GACCGATCGCTATGTATCCGATCGTTTCTTCCCAGATAAGGCGATAGATGCCATGGACGAGGCCGGCGCGAGCGTCCATA
TCACCAATGTGGTGGCTCCGAAAGAAATTGAGATACTGGAGGCCGAATTGACATCGGTGCGAGAGAACAAGCTCTCGGCC
GTAAAGGCTCAGAACTACGAACTGGCTGCCTCCTTCCGCGATCAAGAGCGGCGCACTCAGCAGCAGATAGCGGAAGAGAA
GAAAAAATGGGAAGATCAGATGTCCAAGCACCGCGAGACGGTGGACGAGAATGTAGTGGCGCACGTAGTGGCGTTGATGA
CAGGCGTTCCGGCTGAGCGGCTGAGCACGGGCGAAGGCGAACGTCTGCGCACGATGGCAGATGATCTCAAGACCAAAGTA
GTAGGTCAGGACACAGCCATCGAAAAGATGGTGCGTGCCATCCAGCGCAATCGTCTGGGACTTCGCAATGAAAAGAAACC
GATCGGCTCTTTCCTTTTCCTCGGCCCCACGGGGGTAGGCAAGACCTATTTGGCCAAGAAGCTCGCCGAATACCTGTTCG
AGGATGAGAATGCCATGATCAGGGTGGATATGAGCGAGTATATGGAGAAGTTCTCCGTATCGCGTCTCGTGGGTGCCCCT
CCGGGATATGTGGGCTATGAAGAAGGCGGCCAACTGACGGAGCGCGTAAGACGCAAACCCTATTCCGTGGTTCTCTTGGA
TGAGATCGAAAAGGCGCATGCCGATGTCTTCAATCTGCTCTTACAGGTGATGGACGAAGGTCAGCTGACCGATAGTCTGG
GACGGCGCGTGAATTTCAAGAACACCGTGATCATCATCACCTCCAACGTGGGTACACGCCAGCTCAAAGACTTCGGGCAG
GGTATCGGGTTTCATTCGGAAAAAGACGAGGAAGCGAACAAGGAGCATAGCCGTTCCGTGATCCAAAAAGCCCTGAACAA
GACGTTCAGCCCCGAATTTCTCAACCGTTTGGACGACATCATCCTCTTCGACCAACTGGGCAAGACGGAGATTCGCCGGA
TGGTGGACATAGAGCTTAAATCCGTCTTGGCGCGCATCCATCGTGCCGGATACGACCTCGTCCTTACCGATGAAGCCAAG
GATGTGATAGCGACGAAGGGATACGACCTCCAATACGGAGCACGACCGCTCAAGCGCACACTCCAGAACGAAGTGGAGGA
TCGCCTCACGGATCTTATCCTCTCCGGACAGATCGAGAAAGGGCAGACGCTTACGCTCTCTGCTCGCGATGGCGAGATCA
TCGTACAAGAACAAGCATAA

Protein sequence :
MAYDFTQTFRNSLEYSYQEATRLGVVAVTQDMLVLGIIRDGDNGAIDIMRHYGINLYELKRLIELEAIAESLPASPEGSP
IFTPSAREAINDATDICADMEDEAVSPVHLLLSILNSTQESLVQKIFMKQGIKYDTILSDYFGQRNPSEGKSPSEMEILD
GYQDNDFDDEEDESSPPSGNGGAGRGSGDAPEQNTGGGDTTTTTRSGGDTPALDTFGTDITAMAAAGKLDPVVGREQEIE
RVIQILSRRKKNNPVLIGEPGVGKSAIVEGLAERIVNRKVSRILFDKRIISLDLAQMVAGTKYRGQFEERLKAVLDELKK
NPQIIFFIDEIHTIVGAGSAAGSMDTANMLKPALARGQIQCIGATTLDEYRKNIEKDGALERRFQKVPIAPSTAEETLTI
LQNIKEKYEDYHGVRYTDEAIKAAVELTDRYVSDRFFPDKAIDAMDEAGASVHITNVVAPKEIEILEAELTSVRENKLSA
VKAQNYELAASFRDQERRTQQQIAEEKKKWEDQMSKHRETVDENVVAHVVALMTGVPAERLSTGEGERLRTMADDLKTKV
VGQDTAIEKMVRAIQRNRLGLRNEKKPIGSFLFLGPTGVGKTYLAKKLAEYLFEDENAMIRVDMSEYMEKFSVSRLVGAP
PGYVGYEEGGQLTERVRRKPYSVVLLDEIEKAHADVFNLLLQVMDEGQLTDSLGRRVNFKNTVIIITSNVGTRQLKDFGQ
GIGFHSEKDEEANKEHSRSVIQKALNKTFSPEFLNRLDDIILFDQLGKTEIRRMVDIELKSVLARIHRAGYDLVLTDEAK
DVIATKGYDLQYGARPLKRTLQNEVEDRLTDLILSGQIEKGQTLTLSARDGEIIVQEQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 8e-166 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004508747.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0079 Protein 9e-177 53
clpC YP_004508747.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0080 Protein 1e-148 49