Gene Information

Name : SerAS9_0272 (SerAS9_0272)
Accession : YP_004503695.1
Strain : Serratia plymuthica AS9
Genome accession: NC_015567
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 319294 - 321333 bp
Length : 2040 bp
Strand : +
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain, subgroup; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: spe:Spro_0310 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim dom

DNA sequence :
ATGCAACTCTACTTGTGCGAAAAACCCAGTCAGGGTAAAGATATCGGCGCCATTCTCGGGGCGACGCAGCGAAAGCAGGG
TTACCTGGCGGGAGCCGGCGTCATTGTCACCTGGGCTATCGGGCACCTGCTGGAACAGGCCCAGCCGGAGACCTACGGTG
AGCAGTTCGGCAGTCCCTGGCGGGAGTCCGTTCTTCCTATTGTCCCTACCCAGTGGAAAATGGCGATAAAAAAAGACACT
GCCGATCAGTTCGCTGTCATCCGTGGGTTACTCAAACAGGTTGATTCTGTGGTGATTGCGACCGATGCGGATCGCGAGGG
GGAAGTGATCGCGCGGGAATTACTAGAGCATTGCCACTTTACCGGCCCGGTCCAGCGGCTCTGGTTGTCAGCGCTGGACG
AGGCCAGTATTCGGCATGCCCTGGCGAACAAACTCCCTGGTGAGAAGACCGCGCCCCTGTATGAAGCTGGCCTGGCGCGA
TCACGGGCTGACTGGATGACGGGGATGAACCTGACCCGGCTTTACACGCTCAAAGCCCGCGAGCAGGGATACGGCGAAGT
GTTGTCGATCGGGCGGGTGCAGACCCCCACGCTGGCGCTGGTCGTGAACCGTGACCGCGATATTGCCAACTTCATCTCAA
AACCATACTGGCAAGTCAGGGGCACGCTGCAGAAAGGTGGGATCGCCTTCCCGGCAAACTGGGTACCTGCGGCCAACTAC
TGTGATGAAGAGAAGCGCTGTATTCAACAGAATGTGGCGCAGGCCGTCGTGCAGCGGTGTCAGCAAACGGCTCATGCCGT
TGTGCTTGAGGTGGGGACCGAGCGCAAGAAAGAGTCCGCGCCGTTGGCATTTGATCTGGGCACCCTGCAGCAGGCTTGCT
CCCGCAAGTGGGGGATGAGCGCCAACCAGGTCTTGAGTATCGCACAGTCACTGTATGAGACGCACAAGGCCACCACATAT
CCCCGGACGGATTGCGGCTATCTGCCGACATCGATGCGGGAAGAGGTTGCCGATGTGCTGAGCGCTGTTACCCGCACGGA
CCCAACGCTCAACGAAAGCGTGGCCAGGCTCGACAGGGCTTTTGTTTCCCGTATCTGGAATGACAAAAAAATTACGGCGC
ACCACGGGATTATCCCAACCAAACAGCCGTTCGACCTGAGCAAGTTGTCAGCCGATGAGCTCAAGGTCTATCAGCTGATC
CGTCAGCATTACCTGGCACAGTTCCTGCCCTTACATGAAGTAGATGTGACGGAAGCCACCTTCAATATCGGCGGGCAACT
GTTCCGCACTCGCGGCAAGGTCGAGGCTGTTGCTGGATGGAAAGTGTTGTTCCAGCATGACGTGAGCGAGGCGAAAGAGG
AACCGGCTGACACGGATGATGTCCGGCTGCCGGCGCTGGTTAAAGGGGAAACCGTCGCGGTAGCCGGCGCTGAGCTCAAA
ACGTTGCAGACGAAGCCCCCAGGACATTTCACCGACGGGACACTGATCGCCGCCATGAAAAATGCAGCGGCGTTCGTCAG
TGACCCGCAACTGAAGAAAGTGTTGAAAGAGAACGCAGGGCTGGGTACTGAAGCGACGCGCGCCGGTATCCTGGAGACGC
TGTTTAAACGCGGGTACCTGGAGAAGAAGGGTAAATACCTACTCTCCACACCGATCGCCGGCGAACTGATTGATGCGTTA
CCGACTGCGCTGACCAACCCCGGGATGACGGCGCTGTGGGAGCAGGCGCTGGACGAGATTGCCCAGGGCCAGATGACACT
CGATACGTTCATGAGCCGCCAGGCACAGTGGACAGGGCATCTGGTGGAGAAAGGGAAGACGCAGGCTGTGAAGTTTACCG
CCCCACCTTCACCGCCGTGCCCGACATGCAGTGGGTCGATGCGCCGGCGTGCCGGCAAGAAAGGCGGTGGTGCTTTCTGG
GGCTGCAGTAATTATCCCACTTGCCAGGGGGTCATTAACATCGATGCAAAAGGTGGGCGCAAGGCTAAGCGCTATAAAGC
GAAATCACCGACTAAAAATAAAGCAACAGGATCGGAGTAA

Protein sequence :
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAIKKDT
ADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLAR
SRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRGTLQKGGIAFPANWVPAANY
CDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTY
PRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLI
RQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELK
TLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDAL
PTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFW
GCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 65
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 65
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 65
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 58
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 1e-164 54
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 6e-166 52
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 6e-157 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 6e-155 50
topB AAW83109.1 TopB Not tested GGI Protein 2e-122 43