Gene Information

Name : SerAS12_0844 (SerAS12_0844)
Accession : YP_004499305.1
Strain : Serratia sp. AS12
Genome accession: NC_015566
Putative virulence/resistance : Virulence
Product : L-lysine 6-monooxygenase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3486
EC number : 1.14.13.59
Position : 943220 - 944548 bp
Length : 1329 bp
Strand : -
Note : KEGG: spe:Spro_0919 L-lysine 6-monooxygenase (NADPH)

DNA sequence :
ATGAATCAGCCTCTGGATTTCATCGGCATCGGCATCGGCCCCTTCAACCTCAGCATCGCCGCGCTCGGCAGTGAAGTTGC
CGGCTTTAACGGCAAATTCCTGGAGCGCAAACCGCACTTTTCCTGGCACCCCGGCATGATGGTGCCGGATTGTCATATGC
AGACCAGCTTCCTGAAAGATTTGGTCAGCGCGGTGTCGCCCACCAATCCGTACAGCTTTCTTAACTACCTGGTGAAAAGG
AAGAAATTCTACCGTTTCCTGACCACCGAACTGCGTACGGTGTCGCGCGAAGAGTTCGCCGATTACCTCGACTGGGCCGC
CAACGGGCTGAGTTCGCTCGAGTTCAGCCAGGATATTCAGAGCGTGGATTTTGACGATCGGCAGCGCCAGTTTGTCGTCA
CCACCCAGCGCGCTACCTACCGGGCGCGCCATGTCTGCCTGGGCATCGGCAAGCGCATCAAACTGCCGGACTGCGTTACC
GAGCAAAACGACCGCTGCTTCCACGCCAGCGAGATGACCTTGCGCAACCCGGATCTGACCGGCAAACGCGTCACCATCGT
CGGCGGCGGCCAGAGCGGCGCCGATCTGTTCCTGAACATTTTCCGCGCCGAGTGGGGCCAACCGGCGCAACTGAACTGGA
TCTCGCGCCGCAATAACTACAATGCGCTGGACGAAGCGGCGTTCGCCAACGAGTACTTCACGCCGGACTACGTCGACAGC
TTTTATGGCCTGAACGACAGCGCCAAGCAACGCATGCTGACCGAGCAGAAAATGACCTCCGACGGCATCACCAGCGATTC
GCTGCTGGCCATCTACCGCGCGATGTATCACCAGTTTGAAGTGCTGCGTGAAAAACCCTGGGCGCATCCGCTACCAAGCC
GTTCGCTGGCGGCGATCCACGCTCAGGGTAACGGCTATCAGTTGGTGACTCATCACCACCTCGATCAGGGCAAAGAAACG
TTCGATACCGATGTGGTGATCTTCGCCACCGGTTATCAGCAGGATCGCCCGGCGTTCCTCGCCCCGCTGGCGGAGCGTCT
GCTGACCACGGCCGATGACCAATACCGCGTTGCCCCCGACTTTACCCTCGAGTGGCAGGGCCCACAGGAAAACTGCCTGT
TTGCCGTCAACGCCGGCATGCACAGCCACGGTATCGCCGAACCCCAGCTCAGCCTGATGGCCTGGCGGTCGGCACGCATT
CTCAACCGGGCTTTAGGACGCGACCAGTTCGATTTAACGTCCACCCCGGCTGTGATCCAATGGCGCAGTCAGCAACCAGC
CACCCCGGCCCGCGCTGAACACGTCATGCTCAATTACACCGAGTTTTAA

Protein sequence :
MNQPLDFIGIGIGPFNLSIAALGSEVAGFNGKFLERKPHFSWHPGMMVPDCHMQTSFLKDLVSAVSPTNPYSFLNYLVKR
KKFYRFLTTELRTVSREEFADYLDWAANGLSSLEFSQDIQSVDFDDRQRQFVVTTQRATYRARHVCLGIGKRIKLPDCVT
EQNDRCFHASEMTLRNPDLTGKRVTIVGGGQSGADLFLNIFRAEWGQPAQLNWISRRNNYNALDEAAFANEYFTPDYVDS
FYGLNDSAKQRMLTEQKMTSDGITSDSLLAIYRAMYHQFEVLREKPWAHPLPSRSLAAIHAQGNGYQLVTHHHLDQGKET
FDTDVVIFATGYQQDRPAFLAPLAERLLTTADDQYRVAPDFTLEWQGPQENCLFAVNAGMHSHGIAEPQLSLMAWRSARI
LNRALGRDQFDLTSTPAVIQWRSQQPATPARAEHVMLNYTEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucD AAK71634.1 IucD Virulence SHI-3 Protein 3e-141 61
iucD NP_839220.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 3e-141 61
iucD NP_709457.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 3e-141 61
iucD AAD44749.1 IucD Virulence SHI-2 Protein 2e-141 61
iucD YP_002414043.1 L-lysine 6-monooxygenase Virulence Not named Protein 1e-141 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SerAS12_0844 YP_004499305.1 L-lysine 6-monooxygenase VFG1084 Protein 2e-141 61
SerAS12_0844 YP_004499305.1 L-lysine 6-monooxygenase VFG0618 Protein 1e-141 61
SerAS12_0844 YP_004499305.1 L-lysine 6-monooxygenase VFG0937 Protein 6e-142 61