Gene Information

Name : SerAS12_0810 (SerAS12_0810)
Accession : YP_004499272.1
Strain : Serratia sp. AS12
Genome accession: NC_015566
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 904503 - 907076 bp
Length : 2574 bp
Strand : +
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; Clp ATPase, C-terminal; KEGG: spe:Spro_0886 protein disaggregation chaperone; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGCGTCTGGATCGTCTTACCAACAAATTCCAGCTTGCCCTCGCCGATGCCCAATCTTTAGCCCTTGGGCACGACAACCA
GTTTATGGAACCGTTACATCTGATGAGCGCTCTGCTCACTCAGGAAGGGGGCACGGTTCGTCCATTATTAACTTCAGCCG
GTATCGATAGCGGGCGCGTGCGCACCGAAATCGAACAGGCATTGTCTCGTCTGCCTCAGGTTGAAGGCACTGGTGGTGAC
GTTCAACCGTCCCATGAACTGGTGCGCGTTCTAAACCTGTGCGACAAGCTGGCGCAAAAGCGGGCGGACAAATTCATTTC
TTCCGAACTGTTCGTCCTGGCGGTGCTTGAAGATCGCGGAACCTTGACCGATCTGCTGAAAGCCGCCGGAGCAACAGCCG
ATAAGATCAGTAAGGCCATTGAGCAAATGCGGGGTGGTGACAGCGTGGAAGATCAGGGTGCTGAAGATCAGCGTCAGGCG
TTGAAGAAATACACTATCGATCTGACCGAGCGCGCCGAACAGGGCAAACTTGACCCGGTTATCGGCCGTGACGAAGAGAT
CCGCCGCACTATTCAGGTGTTGCAACGTCGTACCAAGAATAACCCGGTGCTGATCGGCGAGCCTGGCGTGGGTAAAACCG
CGATTGTCGAAGGTCTGGCGCAGCGCATCATTAATGGTGAAGTGCCGGAAGGCCTGAAGCACAAACGCGTGTTGTCCCTC
GACATGGGGGCGTTGATCGCCGGGGCTAAATACCGCGGTGAATTTGAAGAGCGACTCAAAGGCGTACTGAGCGATCTGTC
AAAACAGGAAGGCAGCGTCATTCTGTTTATCGATGAGTTGCATACCATGGTCGGCGCGGGCAAGGCCGATGGCGCAATGG
ATGCCGGCAACATGCTTAAACCTGCGCTGGCGCGTGGGGAACTTCACTGTGTTGGCGCGACTACGTTGAACGAGTACCGT
CAGTATATAGAGAAGGATGCGGCGCTTGAACGTCGTTTCCAGAAGGTCTATGTGGCTGAGCCGAGCGTCGAAGATACCAT
TGCTATCCTGCGCGGCTTGAAGGAGCGTTATGAGCTGCACCACCATGTGCAGATCACCGACCCGGCGATAGTTGCTGCGG
CCACGCTGTCACACCGCTATATCTCCGATCGTCAGTTGCCGGATAAGGCTATCGATCTGATCGATGAGGCGGCGTCAAGT
ATCCGTATGCAGATGGACTCCAAACCGGAATCGCTCGACAGGCTGGAACGCCGCATTATTCAGCTCAAACTGGAACAGCA
GGCGCTGAACAAAGAGTCGGACGACGCCAGCAAGAAACGCCTGGAAATGCTCAGCAGCGAGCTGGAGCAGAAAGAGCGTG
AATATTCAGAATTGGAAGAAGAGTGGAAAGCCGAGAAAGCTTCGCTCTCCGGTACCCAGAATATAAAGGCGGAACTGGAG
CAGGCCAAGATCACTCTGGAGCAGGCGCGTCGCGTCGGCGATCTGGGACGCATGTCTGAACTGCAGTATGGCAAGATCCC
TGAGTTGGAAAAACAGCTCGCCGCCGCTACGCAGGCCGAAGGCAAAACCATGAAGCTACTGCGTAACCGGGTGACTGACG
CGGAAATCGCTGAAGTGCTGGCGCGCGCCACCGGTATCCCGGTAGCCAGAATGTTGGAGGGCGAGCGTGACAAACTGCTG
CGTCTGGAGCAGGAGTTGCATTCGCGGGTGATTGGCCAGGATGAAGCGGTCACTGCGGTATCCAATGCGATCCGTCGCAG
CCGTGCGGGATTGTCTGACCCTAACCGGCCGATCGGCTCGTTCCTGTTCCTCGGCCCGACCGGGGTGGGTAAAACCGAGC
TGTGCAAAGCGTTGGCGTCTTTCCTGTTCGACAGTGACGATGCGATGGTGCGTATCGATATGTCCGAGTTTATGGAGAAA
CATTCGGTATCGCGGCTGGTGGGCGCACCTCCGGGCTACGTTGGTTATGAAGAGGGCGGTTATCTGACCGAGGCCGTGCG
CCGTCGACCTTATTCGGTGATCCTGCTGGATGAAGTGGAGAAAGCTCACCCGGATGTGTTCAACATCCTGCTGCAGGTAT
TGGATGACGGGCGTCTGACCGATGGTCAGGGTCGTACCGTTGATTTCCGCAATACCGTGGTGATCATGACCTCTAACCTT
GGGTCTGACCTGATACAGGAACACTTTGGTCAGATGAACTATGCGCAGATGAAAGAATCGGTTATGGAAATGGTTACCCA
TCATTTCCGTCCGGAATTCATCAACCGTATAGATGAGGTGGTAGTGTTCCACCCGCTCGGCCAGAAGCATATTGCCGAGA
TTGCCAAGATTCAGCTGGCGCGTCTGTATAAGCGTCTTGAGGAGCGTGGTTACGAAGTCACCATGACCGAACCGGCATTG
GCACTGTTGGGCCAAACCGGCTACGACCCTGTTTATGGCGCACGTCCGTTGAAACGCGCTATCCAGCAGGAAATCGAGAA
CCCGTTGGCGCAGCAAATTCTTTCCGGCAAGCTGATCCCGGGCAAACTGGTGACGCTGGATGTGGAAAACGAGCATATCG
TGGCCAGGCAATAA

Protein sequence :
MRLDRLTNKFQLALADAQSLALGHDNQFMEPLHLMSALLTQEGGTVRPLLTSAGIDSGRVRTEIEQALSRLPQVEGTGGD
VQPSHELVRVLNLCDKLAQKRADKFISSELFVLAVLEDRGTLTDLLKAAGATADKISKAIEQMRGGDSVEDQGAEDQRQA
LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKHKRVLSL
DMGALIAGAKYRGEFEERLKGVLSDLSKQEGSVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLNEYR
QYIEKDAALERRFQKVYVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMQMDSKPESLDRLERRIIQLKLEQQALNKESDDASKKRLEMLSSELEQKEREYSELEEEWKAEKASLSGTQNIKAELE
QAKITLEQARRVGDLGRMSELQYGKIPELEKQLAAATQAEGKTMKLLRNRVTDAEIAEVLARATGIPVARMLEGERDKLL
RLEQELHSRVIGQDEAVTAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALASFLFDSDDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQEHFGQMNYAQMKESVMEMVTHHFRPEFINRIDEVVVFHPLGQKHIAEIAKIQLARLYKRLEERGYEVTMTEPAL
ALLGQTGYDPVYGARPLKRAIQQEIENPLAQQILSGKLIPGKLVTLDVENEHIVARQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-103 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 4e-99 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-99 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SerAS12_0810 YP_004499272.1 ATP-dependent chaperone ClpB VFG0079 Protein 3e-145 45