Gene Information

Name : SerAS12_0733 (SerAS12_0733)
Accession : YP_004499195.1
Strain : Serratia sp. AS12
Genome accession: NC_015566
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 824978 - 826168 bp
Length : 1191 bp
Strand : +
Note : TIGRFAM: Methionine gamma-lyase; KEGG: spe:Spro_0798 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

DNA sequence : 
ATGTCTGACACTATCCGACACGCCTTTGCCACACGTGCGATCCACCACGGCTACAATCCTCAGCAATATTTGGGGGCGCT
TTGTCCACCGGTCTTTATGAGTTCGACCTTTGCCTTTCCTACGGCAGAATACGGTGGTGCCTGCTTTGCCGGCAGCGAGC
CGGGCTATTTTTATTCGCGCATCGCCAACCCGACGCTAAATCTGCTGGAACAGCGGATAGCCAACCTGGAGGGCGGTGAG
GCGGCGGTGGCGTTTTCTTCCGGTATGGGGGCGATCACCGCCTGTTGCTGGACGCTGCTGGCGCCGGGAGATGAGCTGAT
CGTCGATGAAACCATTTATGGCTGCACTTTCAGCTATTTTCATCAGGGTCTGGCGCGTTTTGGCGTCAAGGTTACGCACG
TCGATCTGACGCAGCCGGAAAAACTGGCCGCAGCCATAGGGCCACGTACCCGTTTGGTGTACTGCGAAACGCCGGCCAAC
CCCAATATGCGGTTGATCGATATTGCCGCGGTGGCGGAGATTACTCATCGGCAGCAGGCGCTGCTGCTGGTGGATAACAC
GTATTGCACGCCCTATCTGCAACAACCGTTGGCGCTTGGGGCTGACATCGTGGTGCATTCCGCCACCAAGTATATCGGCG
GCCACGGGGATTTACTGGCCGGGTTGGCGGTGACCCGTCAGGATTTGGCGCAGAATATCCGGTTGGTGGGACTGAAGGAT
ATGAACGGCGCGGTATTGTCGGCGCAGGATGCCGCGCTGCTGTTGCGCGGTTTGAAAACCCTGCCGCTGCGCATGGAACG
CCACTGCGATAACGCTCAGCGGTTGGCGGAAATGCTGGTTCAGCATCCTGCGGTAGAGCAGGTGTATTATCCGGGGTTGG
AGACTTTCCCGCAGTACCCTTTGGCGCAGCGGCAGATGACGCGTCCTGGCGGCATGATCGCTTTTGAACTGAAGGGCGGT
ATGGCGGCGGGCATTCGTTTCCTCAATGCGTTGCAGTTAATCTTGCGTGCCGTCAGCCTGGGGGATTGCGAAACGCTGGC
GCAGCATCCGGCGAGCATGACCCATTCCGCTTACAGCGCGGAAGAGCGTCAGCGACATCATATCAGCGATGGATTGATTC
GCCTGTCGGCGGGCCTGGAAGACATAGAGGATTTGTGCGCCGATATCGAACAGGCGCTGGCACAGGCGTAA

Protein sequence : 
MSDTIRHAFATRAIHHGYNPQQYLGALCPPVFMSSTFAFPTAEYGGACFAGSEPGYFYSRIANPTLNLLEQRIANLEGGE
AAVAFSSGMGAITACCWTLLAPGDELIVDETIYGCTFSYFHQGLARFGVKVTHVDLTQPEKLAAAIGPRTRLVYCETPAN
PNMRLIDIAAVAEITHRQQALLLVDNTYCTPYLQQPLALGADIVVHSATKYIGGHGDLLAGLAVTRQDLAQNIRLVGLKD
MNGAVLSAQDAALLLRGLKTLPLRMERHCDNAQRLAEMLVQHPAVEQVYYPGLETFPQYPLAQRQMTRPGGMIAFELKGG
MAAGIRFLNALQLILRAVSLGDCETLAQHPASMTHSAYSAEERQRHHISDGLIRLSAGLEDIEDLCADIEQALAQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-54 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-55 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SerAS12_0733 YP_004499195.1 methionine gamma-lyase BAC0207 Protein 2e-124 66