Gene Information

Name : SerAS12_3963 (SerAS12_3963)
Accession : YP_004502371.1
Strain : Serratia sp. AS12
Genome accession: NC_015566
Putative virulence/resistance : Virulence
Product : lysine decarboxylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 4229446 - 4231602 bp
Length : 2157 bp
Strand : -
Note : KEGG: spe:Spro_3773 lysine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase, N-terminal; Orn/Lys/Arg decarboxylase, C-terminal

DNA sequence :
ATGAATATCATCGCAATCATGAGCCCAACGGGCGTCTATTACAAAGATGAGCCTATTCGTGAGCTGCACACTGCATTGGC
TACGATGGGTTTCCAGTTGGTTTACCCGAAGAATGGCGGCGATCTGCTGAAGCTGATCGAGGCCAATGCGCGTATTTGCG
GAGTGATTTTCGACTGGGACGACTACAGCCTGGAGCTGTGCAGCGAAATTAACGAGCTGAATGAATATCTACCGCTATAT
GCGTTTATCAACCAGTATTCCACCTTCGACGTCAGTCTTCATGAAATGCGCATGGTGCTGTATTTCTTTGAGTATGGCTT
GAATGCGGCAGATGATATTGCGCAGCGTATCCAGCAATACACCGCAGAATATATCGACACCATTACGCCGCCCTTAACCA
AGGCACTATTCAACTACGTGCGCGAGGGCAAATACACCTTTTGCACCCCAGGGCATATGGCCGGCACTGCCTTCCAGAAA
AGCCCGGTTGGCTGCCTGTTTTACGATTTTTTCGGTGCGAACACCTTAAAAGCCGACGTCTCCATATCGGTGACCGAACT
GGGTTCGCTGCTGGACCATACCGGCCCGCATCTGGAGGCCGAAGAGTATATTGCGCGTACCTTTAACGCCGAGCAGAGCT
ATCTGGTGACCAACGGCACCTCCACCGCCAACAAGATTGTCGGCATGTATTCGGCCCCGGCAGGCAGCACGGTGTTGATT
GACCGCAACTGCCATAAATCGCTGTGTCATCTGCTGATGATGAGCGATATCGTCCCGATCTACCTGCGTCCGCTGCGTAA
CGCCTACGGCATTCTTGGTGGCATCCCGCAGCATGAATTTACCCATGAGAGCATTGCCGGTCGAGTCGCCGCCACCGCGA
ATGCCAGTTGGCCGGTACATGCGGTGATTACCAACTCAACCTATGACGGCCTGCTGTATAACACCGATTACATCAAGCAG
ACGTTGGACGTGCCATCAATCCATTTTGACTCCGCCTGGGTACCCTATACCAACTTCCATCCGATCTACGAAGGCAAGAG
CGGCATGAGCGGCGAGCGCACGCCCGGCAAGGTGATCTACGAAACGCAGTCCACGCACAAGCTGCTGGCGGCATTCTCGC
AGGCCTCGATGATTCACATTAAAGGCGATTACGACGAAAGCACCTTTAACGAAGCCTATATGATGCATACCACCACTTCG
CCGAACTACGGCATTGTGGCGTCGATGGAGACTGCCGCCGCGATGCTGCGCGGCAATCCTGGCCGGCGGTTGATTAACCG
CTCGGTAGAGCGTGCATTGCATTTCCGTCGTGAGGTGCAGCGGTTGCGGGAGGAGAGCGATAGCTGGTTCTTCGATATCT
GGCAGCCTGAAGAGATCGACGAGGCGCAATGCTGGCCGTTGAACCCGGACGATAATTGGCATGGGTTTGGCAATACCGAC
AGCGATCACATGTATCTCGATCCGATCAAAGTGACGATCCTGACGCCGGGAATGAACGAACTGGGTACGCTGGAGGGGAG
CGGGATCCCGGCGGCGCTGGTGGCGAAATACCTGGACGAGCGCGGCATCGTGGTGGAAAAAACCGGGCCTTATAATCTGC
TGTTCCTGTTCAGTATCGGCATTGATAAAACCAAGGCGATGAGCCTGCTGCGTGGCCTGACCGATTTTAAACGCGCTTAC
GATCTTAATCTGCGGGTGAAGAACATGCTGCCGGATCTGTATGCGGAGGATCCTGATTTCTATCGCAATATGCGCATTCA
GGATCTGGCAGCCGGGATCCACCGGTTGATCTGCCTGCACGATCTGCCGCGGCTGATGCTGCGGGCGTTCGACGTGCTGC
CGGAAATGAAGCTGACGCCACACCAAATGTTCCAGCAGCAGGTACGTGGCAATGTGGAAACCTGCGAACTGGATCAACTG
GTGGGCAAGGTGGCGGCCAATATGATCCTGCCTTATCCACCAGGCGTGCCGTTAGTGATGCCGGGTGAGATGATCACCGA
GGAGAGCCGTGCGGTGCTCGATTTCTTGCTGATGCTGTGTTCTATCGGCGAGCGTTATCCCGGCTTTGAAACCGATATCC
ACGGTGCGAAATTGACCGAGGATGGGCGTTATCTGGTGAAGGTACTGAAAACGCCGCCGCCCGATCTCAACGTTTGA

Protein sequence :
MNIIAIMSPTGVYYKDEPIRELHTALATMGFQLVYPKNGGDLLKLIEANARICGVIFDWDDYSLELCSEINELNEYLPLY
AFINQYSTFDVSLHEMRMVLYFFEYGLNAADDIAQRIQQYTAEYIDTITPPLTKALFNYVREGKYTFCTPGHMAGTAFQK
SPVGCLFYDFFGANTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFNAEQSYLVTNGTSTANKIVGMYSAPAGSTVLI
DRNCHKSLCHLLMMSDIVPIYLRPLRNAYGILGGIPQHEFTHESIAGRVAATANASWPVHAVITNSTYDGLLYNTDYIKQ
TLDVPSIHFDSAWVPYTNFHPIYEGKSGMSGERTPGKVIYETQSTHKLLAAFSQASMIHIKGDYDESTFNEAYMMHTTTS
PNYGIVASMETAAAMLRGNPGRRLINRSVERALHFRREVQRLREESDSWFFDIWQPEEIDEAQCWPLNPDDNWHGFGNTD
SDHMYLDPIKVTILTPGMNELGTLEGSGIPAALVAKYLDERGIVVEKTGPYNLLFLFSIGIDKTKAMSLLRGLTDFKRAY
DLNLRVKNMLPDLYAEDPDFYRNMRIQDLAAGIHRLICLHDLPRLMLRAFDVLPEMKLTPHQMFQQQVRGNVETCELDQL
VGKVAANMILPYPPGVPLVMPGEMITEESRAVLDFLLMLCSIGERYPGFETDIHGAKLTEDGRYLVKVLKTPPPDLNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 76
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SerAS12_3963 YP_004502371.1 lysine decarboxylase VFG1670 Protein 0.0 64