Gene Information

Name : SerAS12_2750 (SerAS12_2750)
Accession : YP_004501178.1
Strain : Serratia sp. AS12
Genome accession: NC_015566
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 2947830 - 2949755 bp
Length : 1926 bp
Strand : -
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain, subgroup; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: spe:Spro_2718 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim dom

DNA sequence :
ATGCGACTGTTTATTGCCGAGAAACCGAGTTTGGCGCGCGCCATTGCCGACGTTCTTCCCAAACCGCATCGCCGCGGTGA
CGGGTTTATTGCCTGTGGCAACAATGATGTGGTCACCTGGTGTGTGGGCCATTTACTAGAGCAGGCGCAGCCGGATGCCT
ACGATAGCCGCTATGCGCGCTGGTCGCTGGCGGATCTGCCCATTATCCCCGAAAAGTGGCAACTGCAGCCGCGTCCCTCG
GTCAGTAAACAGCTTAATGCGATTAAAAAGCTATTACATGACGCTGACGAGGTAGTGCATGCGGGTGACCCGGATCGCGA
AGGACAATTGCTGGTGGACGAAGTGCTGGACTATCTGGCGCTGACACCGGAAAAACGTCACAGCGTACGCCGTTGCCTGA
TTAACGATCTCAACCCGCAGGCGGTGGAGCGCGCTATCGATCGGCTGCGTGACAACCGCGACTTTATCCCGCTGTGCGTC
TCTGCGCTGGCGCGTTCCCGCGCTGACTGGCTGTATGGCATCAACATGACCCGCGCCTATACCATTTTAGGGCGAAATGC
CGGCTACGACGGCGTGTTGTCCGTTGGGCGGGTGCAAACGCCGGTGTTGGGGTTAGTCGTGCGGCGTGATGAAGAAATTG
AAAACTTTGTGCCAAAAGACTTCTTTGAAGTTAAAGCGCACATAGTGACGCCAAAGGAAGAGCGCTTTGTCGCGCTTTGG
CAGCCGAGTGACTCTTGTGAACCTTATCAGGATGAAGAAGGGCGTTTGCTGCACCGGCCGCTGGCGGAGCACGTGCTTAA
ACGCATCGAGGGCCAGCCGGCGCTGGTCACGTCTTATAATGATAAACGGGAATCAGATACCGCGCCGCTGCCGTTTTCGC
TCTCGACGCTGCAAATTGAGGCTTCCAAACGTTTCAACCTGAGTGCGCAGCAGGTGCTGGATATCTGCCAGCGGTTGTAT
GAAACGCATAAATTGATCACCTATCCGCGTTCCGACTGCCGCTACCTGCCGGAAGAACATTTCGCCGGGCGTCACGCGGT
GCTTAACGCGATCAGCGCACATCAGCCGGATCTTTACCCGCAGCCGGTGATCGACAGCGATCGTCGCAACCGTTGCTGGG
ACGATAAAAAAGTTGATGCTCACCATGCCATTATTCCCACTGCCCGCGCCAGCAAAGTGAGCCTCAGCCAGGACGAGCTG
AACGTCTACGGGTTGGTGGCGCGCCAGTACCTGATGCAGTTTTGCCCGGATGCCATGTTCCGCAAATGCGTGATTGAACT
GGATATCGCCGGGGGAAAATTCGTTGCCAAGGCGCGTTTCCTGGCCGAAGCGGGCTGGCGGACGCTGCTGGGCAGCAAAG
AGCGCGATGAAGAAAATGAAGGTTCTCCGCTGCCGGTGGTGGCGAAAGATGATGAGCTATTGTGCGAACGTGGTGAGGTG
GTGGAACGCCAGACTCAGCCTCCGCGGCCTTTCACCGATGCCAGTCTGCTTTCTGCTATGACCGGCATAGCGCGTTTCGT
ACAAGATAAAGCGCTAAAGAAAATCCTGCGAGCGACCGATGGTTTAGGTACCGAGGCGACGCGTGCGGGCATCATTGAGT
TGCTGTTCAAGCGGGCGTTTTTGTACAAGAAAGGACGCTATATTCATTCCAGCGAAACCGGCCGGGCGTTGATCCATTCG
CTGCCGGATATTGCCGCTCGCCCTGATATGACGGCCAACTGGGAGGCTACGTTGACGCAAATCAGTGAAAAATCCTGCCG
CTATCAGGACTTTATGCAACCCTTGGTAGGCACTTTGCAGGAGCTGATTTATCAGGCCAAGCAAAGCCGGGCGAGTATGG
CGTTTCGCGGGTTGCCGCCGTCGCCTTCCGCCGGGGCAAAAAAACGCAAGAAAAGCGCCGGCAAGGCGCGGGAGAAAAGC
GAGTGA

Protein sequence :
MRLFIAEKPSLARAIADVLPKPHRRGDGFIACGNNDVVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPS
VSKQLNAIKKLLHDADEVVHAGDPDREGQLLVDEVLDYLALTPEKRHSVRRCLINDLNPQAVERAIDRLRDNRDFIPLCV
SALARSRADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIENFVPKDFFEVKAHIVTPKEERFVALW
QPSDSCEPYQDEEGRLLHRPLAEHVLKRIEGQPALVTSYNDKRESDTAPLPFSLSTLQIEASKRFNLSAQQVLDICQRLY
ETHKLITYPRSDCRYLPEEHFAGRHAVLNAISAHQPDLYPQPVIDSDRRNRCWDDKKVDAHHAIIPTARASKVSLSQDEL
NVYGLVARQYLMQFCPDAMFRKCVIELDIAGGKFVAKARFLAEAGWRTLLGSKERDEENEGSPLPVVAKDDELLCERGEV
VERQTQPPRPFTDASLLSAMTGIARFVQDKALKKILRATDGLGTEATRAGIIELLFKRAFLYKKGRYIHSSETGRALIHS
LPDIAARPDMTANWEATLTQISEKSCRYQDFMQPLVGTLQELIYQAKQSRASMAFRGLPPSPSAGAKKRKKSAGKAREKS
E

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-111 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 6e-104 41