Gene Information

Name : SerAS12_2496 (SerAS12_2496)
Accession : YP_004500926.1
Strain : Serratia sp. AS12
Genome accession: NC_015566
Putative virulence/resistance : Virulence
Product : L-lysine 6-monooxygenase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3486
EC number : 1.14.13.59
Position : 2684597 - 2685922 bp
Length : 1326 bp
Strand : -
Note : KEGG: spe:Spro_2520 L-lysine 6-monooxygenase (NADPH)

DNA sequence :
ATGAACCAGCGTTTGGACTTTATCGGCATAGGTATTGGCCCGTCCAACCTCAGTCTTGCTGCGCTTGGAAGCGAAATCGA
GGGTTTCAATTGCAGATTCCTCGAACGTAAACCGCACTTTTCCTGGCACCCGGGCATGATCCTGGCAGATAGCAATATGC
AGACCCATTTTTTGAAGGATCTGGTCACTGCCGTCTCGCCAACCAACCCTTATAGTTTTCTCAACTATCTGGTGAAGAGT
AAAAAGTTCTACCGCTTCCTGACGACTGAACAGCGTACAGCGTCGCGCGAAGAGTTTGCCGATTATCTCAACTGGGCGGC
AACGGGTTTGGATTCGCTGATGTTCAACCAAGAGGTTCGCCATGTGGACTTTGATGACGAACAGCGGCAGTTTGTCGTCT
CCACCCAGAATGACGTGCTTTACGCTAAACACCTGTGTGTGGGCATAGGCAAGCAAATCAAACTGCCGGACTGTGTGACC
GAGCAAAATGATCAATGCTTTCACGCCAGCGAAATGATGTTGCGCCAGCCAAACCTTGCCGGAAAACGCGTGGTCATTGT
GGGCGGCGGTCAAAGCGGTGCTGACCTGTTCTTGAATATTTTCCAGGGAGAATGGGGCCGGCCAGAACAACTTGGCTGGA
TATCTCGGCGCAACAACTACAACGCACTTGATGAAGCCGCCTTTGCCAACGAGTATTTTACGCCAGATTATGTCGACAAC
TTCTACACGCTCGGCCACGCGGCCAAAGAACACATGCTGCAAGAACAAAAGATGACTTCCGATGGGATCACCAGCGAGTC
TCTGTTGGCAATTTATCGCGCCATGTATCACCACTTCGATGTACTCCGTGAGCAACGATGGGTGCGCCTGCTGCCCAGCC
GTTCAGTGACGGCCCTTAATGCCAAAGATAATGCTTATCGGCTAGAGACGCTGCATCACCTTGACCAAGGGCGAGAAAGC
TTTGATGCAGACGTGGTCATTTTTGCGACTGGCTATGAACAGGCCCGCCCGGCATTTCTTGATTCCCTGGCTGACCGTTT
GTTAACCACCCCCGATGGGCAATACCGTATTGCTTCTGATTTTACCCTTGAGCGGGAAGGGGAACATGACAATTGCTTGT
TTGCCGTTAACGCCAGCATGCATCACCACGGCATTGCCGATCCGCAGCTTAGCCTGGTGGCCTGGCGATCGGCACGTATT
CTCAATCGAGCTTTAGGCCATAACCAATTTGATTTGAGCACCACTCCGACGATGATTCAATGGCGCAGTGAGCAAGAACA
ACCCGTCGCTTTAAACCCCTTGATGGCCTCTTGGTCACCCCTTTAA

Protein sequence :
MNQRLDFIGIGIGPSNLSLAALGSEIEGFNCRFLERKPHFSWHPGMILADSNMQTHFLKDLVTAVSPTNPYSFLNYLVKS
KKFYRFLTTEQRTASREEFADYLNWAATGLDSLMFNQEVRHVDFDDEQRQFVVSTQNDVLYAKHLCVGIGKQIKLPDCVT
EQNDQCFHASEMMLRQPNLAGKRVVIVGGGQSGADLFLNIFQGEWGRPEQLGWISRRNNYNALDEAAFANEYFTPDYVDN
FYTLGHAAKEHMLQEQKMTSDGITSESLLAIYRAMYHHFDVLREQRWVRLLPSRSVTALNAKDNAYRLETLHHLDQGRES
FDADVVIFATGYEQARPAFLDSLADRLLTTPDGQYRIASDFTLEREGEHDNCLFAVNASMHHHGIADPQLSLVAWRSARI
LNRALGHNQFDLSTTPTMIQWRSEQEQPVALNPLMASWSPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucD AAD44749.1 IucD Virulence SHI-2 Protein 3e-130 60
iucD NP_839220.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 4e-130 60
iucD NP_709457.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 4e-130 60
iucD YP_002414043.1 L-lysine 6-monooxygenase Virulence Not named Protein 5e-130 59
iucD AAK71634.1 IucD Virulence SHI-3 Protein 6e-130 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SerAS12_2496 YP_004500926.1 L-lysine 6-monooxygenase VFG0618 Protein 2e-130 60
SerAS12_2496 YP_004500926.1 L-lysine 6-monooxygenase VFG1084 Protein 3e-130 59
SerAS12_2496 YP_004500926.1 L-lysine 6-monooxygenase VFG0937 Protein 2e-130 59