Gene Information

Name : SerAS12_2129 (SerAS12_2129)
Accession : YP_004500563.1
Strain : Serratia sp. AS12
Genome accession: NC_015566
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2288374 - 2289786 bp
Length : 1413 bp
Strand : -
Note : TIGRFAM: Pyruvate kinase; KEGG: spe:Spro_2187 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta

DNA sequence : 
ATGAAAAAGACCAAAATTGTTTGTACCATCGGTCCAAAAACCGAATCGGAAGAAATGCTGACCAACCTGCTCAATGCAGG
CATGAACGTAATGCGCCTCAACTTCTCCCACGGCGATTATGAAGAACATGGCAACCGCATCAAGAACATGCGCGCCGTGA
TCGCGAAAACCGGCAAAAACGCCGGTATCCTGCTGGATACCAAAGGCCCGGAAATCCGCACCATGAAGTTGGAAGGCGGT
AAAGACGCGGCGCTGGTTGCCGGCCAGACCTTCACTTTCACCACCGATCAAAGCATTATCGGCAATAACGAACGCGTTGC
GGTCACCTACGCCGGTTTCTCCGCCGATCTGAAAATCGGCAATACCGTGCTGGTTGACGATGGCCTGATCGGCATGGAAG
TCACTAACGTGACCGAAAACGAAGTGATCTGTAAGGTACTGAACAGCGGCGATCTGGGCGAAAACAAAGGCGTTAACCTG
CCGGGCGTTTCCATCCAACTGCCTGCATTGGCGGAAAAAGACAAACGCGACCTGATTTTCGGCTGTGAACAAGGTGTCGA
CTTCGTTGCCGCGTCCTTTATCCGCAAACGCTCCGACGTGCTGGAAATCCGCGAACATCTGAAAGCCCACGGCGGCGCGC
AGATTCAGATCATCTCCAAAATTGAAAACCAGGAAGGCCTGAACAATTTCGACGAGATCCTCGAAGCCTCTGACGGCATC
ATGGTAGCTCGTGGCGATCTGGGCGTAGAAATCCCGGTAGAAGAAGTGATCTTCGCTCAGAAGATGATGATCGAAAAATG
TAATCGCGCACGTAAAGTGGTGATCACCGCCACCCAAATGCTGGATTCGATGATCAAGAACCCGCGCCCTACCCGTGCTG
AAGCCGGCGACGTGGCGAACGCCATTCTGGACGGTACCGACGCCGTTATGCTGTCAGGCGAGAGCGCCAAGGGCAAATAC
CCGCTGGAAGCCGTGACCATTATGGCCACCATCTGCGAGCGCACCGATCGCGTGATGCCGAGCCGTATTGACAGCCTGAA
CGACAACCGCAAACTGCGCATCACCGAAGCCGTCTGCCGTGGCGCCGTTGAAACCGCAGAAAAACTGGATGCGCCATTGA
TTGTGGTTGCCACCAGCGGCGGTAAATCAGCCAAATCCGTGCGTAAATACTTCCCTAACGCCGTGATCCTGGCGCTGACC
ACCAACGAAGTCACCGCTCGCCAATTGATCCTGACCAAAGGCGTTACGCCGCAAATGGTCAAAGAAATCGCCTCTACCGA
CGACTTCTATCGCATTGGCAAAGAAGCTGCGCTGGCCAGCGGCCTGGCGCAAAAAGGCGACGTTGTGGTGATGGTTTCTG
GCGCTCTGGTACCGAGCGGCACCACCAATACTGCCTCGGTTCACGTGCTGTAA

Protein sequence : 
MKKTKIVCTIGPKTESEEMLTNLLNAGMNVMRLNFSHGDYEEHGNRIKNMRAVIAKTGKNAGILLDTKGPEIRTMKLEGG
KDAALVAGQTFTFTTDQSIIGNNERVAVTYAGFSADLKIGNTVLVDDGLIGMEVTNVTENEVICKVLNSGDLGENKGVNL
PGVSIQLPALAEKDKRDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGAQIQIISKIENQEGLNNFDEILEASDGI
MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY
PLEAVTIMATICERTDRVMPSRIDSLNDNRKLRITEAVCRGAVETAEKLDAPLIVVATSGGKSAKSVRKYFPNAVILALT
TNEVTARQLILTKGVTPQMVKEIASTDDFYRIGKEAALASGLAQKGDVVVMVSGALVPSGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 0.0 88
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 0.0 88
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 0.0 88
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 0.0 87

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SerAS12_2129 YP_004500563.1 pyruvate kinase VFG0479 Protein 0.0 88