Gene Information

Name : Desca_0745 (Desca_0745)
Accession : YP_004496542.1
Strain : Desulfotomaculum carboxydivorans CO-1-SRB
Genome accession: NC_015565
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 819733 - 821448 bp
Length : 1716 bp
Strand : +
Note : PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; TIGRFAM: Urease, alpha subunit; HAMAP: Urease, alpha subunit; KEGG: tjr:TherJR_0607 urease, alpha subunit

DNA sequence :
ATGACCTTAAAAATGACCAGGCAGGAATATGCGGATATGTTTGGCCCGACAGTAGGGGATAAGGTGCGCTTGGCGGATAC
CGATATCATTATAGAGGTAGAAAAAGATTATAGCGTTTATGGAGATGAGTGCAAGTTTGGTGGGGGCAAAGTGATCAGGG
ACGGCATGGGGCAAACCCCTAATGCTACCAGGGCAGAAGGGGCCTTGGATTTAGTGATCACCAATGCCTTGATTTTGGAC
TACTGGGGTATTGTTAAAGCCGACATTGGCATCAGGGACGGTAAAATTGCCGGGATTGGTAAGGCCGGGAACCCTAATTT
AATGGACGGGGTGGATGGTAACCTGATTATCGGAGCTTCTACTGAGGTTGTTGCCGGAGAAGGGCTTATTGTCACTCCCG
GCGGGGTGGACGCACACATTCACTTTATTTGTCCCCAGCAAATTGAAGTGGCCATTGCTTCTGGGATAACCACCATGATC
GGAGGTGGTACCGGTCCTGCTACGGGGACCAATGCTACCACTTGTACCCCGGGGGCTTGGAATATCCACCGGATGTTGGA
AGCAGCAGAGCAGTTCCCGGTAAACCTGGGTTTTTTGGGTAAGGGTAATAGTTCATTTGAAAAGCCTTTAATTGAACAAA
TCACAGCAGGAGCCATGGGGCTGAAGCTCCATGAAGATTGGGGAACTACCCCGGTAGCCATTGATACCTGCTTAAAAGTG
GCTGATGCTTATGATGTGCAGGTGGCCATCCATACCGATACTTTAAATGAAGCCGGGTTTGTGGAGGATACCATTACCGC
TATTAACGGCCGGACCATCCACACTTACCATACGGAAGGGGCCGGTGGAGGCCATGCTCCGGATATTATTAAAATCGCGG
CGGAACCTAATATATTGCCTTCCTCAACTAATCCAACAAGGCCCTATACGGTGAATACCATTGATGAACATTTAGATATG
TTGATGGTTTGCCATCACTTGGATAGCAAGGTGCCTGAGGATGTAGCCTTTGCAGATTCTCGGATTCGGGCGGAGACCAT
TGCAGCGGAAGATATTCTCCATGATTTAGGAGTCTTCAGTATGATCAGTTCCGATTCCCAGGCTATGGGACGGGTTGGGG
AAGTTATTATACGCACATGGCAGACTGCTGATAAAATGAAAAAACAGCGGGGCCCGCTGCCTGAAGACAAGGGTAATGAT
AATTTCCGGGCCAAGCGCTATATTGCCAAATACACTATTAATCCGGCCATTACTCATGGTATCAGTGATTATGTTGGTTC
CATTGAAATTGGTAAACTGGCGGATCTTGTGTTGTGGCAGCCCAAATTTTTCGGGGTTAAACCAGAGATGGTAATTAAGG
GTGGCATGATTGCTTTTAGCCAAATGGGAGATGCCAATGCATCTATTCCAACTCCTCAGCCGGTGATAAGCCGTCTGATG
TTTGGAGCTTTGGGCCGGGCTAAATATACTACCAGCTTAACCTTTGTCTCTAAAGCTGCTTATGATGCGGGTATTAAGGA
ACAACTCAAGTTGGAGAAGCAAGTGGTACCGGTGAAAAATTGCCGCAGTGTATCTAAAAGCCAAATGATCCACAATAACA
AGACTCCGGAAATTTTGGTGGATCCGGAAACATATGAAGTAAGAGTTAATGGGGAGTTGTTAACCTGCGGGCCGGCTAAA
GAGCTAGCGATGGCTCAGCGATATTTTCTCTTTTGA

Protein sequence :
MTLKMTRQEYADMFGPTVGDKVRLADTDIIIEVEKDYSVYGDECKFGGGKVIRDGMGQTPNATRAEGALDLVITNALILD
YWGIVKADIGIRDGKIAGIGKAGNPNLMDGVDGNLIIGASTEVVAGEGLIVTPGGVDAHIHFICPQQIEVAIASGITTMI
GGGTGPATGTNATTCTPGAWNIHRMLEAAEQFPVNLGFLGKGNSSFEKPLIEQITAGAMGLKLHEDWGTTPVAIDTCLKV
ADAYDVQVAIHTDTLNEAGFVEDTITAINGRTIHTYHTEGAGGGHAPDIIKIAAEPNILPSSTNPTRPYTVNTIDEHLDM
LMVCHHLDSKVPEDVAFADSRIRAETIAAEDILHDLGVFSMISSDSQAMGRVGEVIIRTWQTADKMKKQRGPLPEDKGND
NFRAKRYIAKYTINPAITHGISDYVGSIEIGKLADLVLWQPKFFGVKPEMVIKGGMIAFSQMGDANASIPTPQPVISRLM
FGALGRAKYTTSLTFVSKAAYDAGIKEQLKLEKQVVPVKNCRSVSKSQMIHNNKTPEILVDPETYEVRVNGELLTCGPAK
ELAMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-175 69
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-175 69
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-162 63
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-163 63
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 7e-163 63
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-163 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desca_0745 YP_004496542.1 urease subunit alpha VFG0270 Protein 1e-173 69