Gene Information

Name : Desca_0171 (Desca_0171)
Accession : YP_004495987.1
Strain : Desulfotomaculum carboxydivorans CO-1-SRB
Genome accession: NC_015565
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 188993 - 191590 bp
Length : 2598 bp
Strand : +
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: tjr:TherJR_0928 ATP-dependent chaperone ClpB; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGGAATTTAATCGCTATACCCAAAAATCACGGGAAGCTGTGGCAGCAGCGCAGAATTTAGCTGCCCAGTGGCACCATCA
AGAAATAAACGGGAAACATTTACTGATGGCTTTGTTAACCCAGGAAGGTGGCTTAACTCCTCGTTTTCTGGAACACGCCG
GGGTAAATGTGGGTGTCCTGCAAAATCTGGTGCAGGGGTTGTTAAGAAAGGCACCCGCGGTCCATGGATATGAAGGTGCC
TTACGGTTGGGCACTGGTTTAGCCAGGGTCTTTACCCGGGCGGAAAAAGAGGCCGGGGATATGAAAGACCAGTATATCAG
TGTGGAGCATCTATTACTGGCCCTGCTGGAAGAAGGGGAGAATGAGCTTAAGGAAGTCTTCCGTCAGGTGGGCTTGAGCC
GGGAAACCCTGCTCAATTCACTACGGGCCATTCGAGGCAACCAGCAGGTAACCAGCGAAAATCCCGAAGAAACTTACGAA
GCCCTGGAGAAGTACGGGCGAGATTTAACCAGACTGGCGAAGGAAGGTAAATTAGACCCGGTCATTGGTCGGGATGATGA
AATCCGCCGCACGGTAGAAATTTTGTCCCGCCGCACCAAGAACAACCCTGTTTTGATTGGCGAACCCGGTGTGGGGAAAA
CCGCCATTGTAGAAGGTTTAGCCCGGCGTATTGTGGCCGGGGATATACCGGAAGGCCTAAAAAACAAACGGGTGATTGCC
CTGGATATGGGGGCCCTGATTGCCGGGGCCAAATACCGGGGAGAATTTGAAGAACGACTTAAGGCAGTGTTAAAAGAGGT
TCAACGGTCCAACGGAGGTATTATCCTCTTTATAGATGAGTTGCATACGGTGGTGGGGGCCGGGGCTGCCGAAGGAGCCA
TGGATGCGGGTAATTTATTAAAACCCATGCTGGCCCGGGGCGAACTGCGAGCCATTGGTGCCACCACCCTGGATGAATAT
CGCAAGCATGTAGAAAAGGATGCCGCCCTGGAGAGACGATTTCAGCCGGTAATGGTCAACCCGCCTACGGTGGAAGATAC
CATCTCAATTTTAAGAGGCTTAAAGGAACGGTACGAGATACACCACGGGGTGCGGATTAAGGACAGTGCCCTGGTGGCGG
CCGCCACCCTGTCTGACCGCTATATCTCCGACCGGTTTTTACCGGACAAGGCTATTGACCTGATGGATGAGGCCGCGGCC
CGACTGCGTACGGAGATAGATAGTATGCCTACTGCCTTAGATGAAATTACCCGCCGGATCATGCGGCTGGAGATTGAAGA
GGCGGCCCTAAAAAAAGAAAAGGACCCTATTTCCCAGGAACGATTAGAAAAATTACAAGAACAATTGGCCAACCTGCGGA
GTGAAGCAGATGTTATGCGAACCCAATGGGAAGTAGAAAAACAAGCCATTTCCCGGGTCCGCCAACTGAAAAAGGAGATT
GAAGAAACCAAGCTGGCCATTGAAAGGGCGGAAAGGGAATACGACCTTAACCGAATGGCCGAGTTAACCTATGGCAAGTT
ACCTGAGCTGGAGAAAAAGTTAAAGTCGGAAGAAGAGTTACTGGCGGGTAAAGAAAAGCACCATCGTTTGTTAAAAGAAG
AAGTCGATGAGGAAGACATTGCCCGGGTGGTCAGCCGGTGGACCGGCATCCCCTTAGAAAAATTAATGGAGGGGGAAAAG
GAAAAACTCATTCACTTAGATGAATTACTGCACCGGCGGGTAATTGGCCAGCATGAGGCGGTACAGGCGGTGGCTGATGC
GGTACTAAGGGCCCGGGCCGGTATTAAAGATCCCAACCGTCCCATCGGCAGTTTTATTTTCCTGGGGCCCACCGGAGTAG
GTAAAACTGAACTGGCCAGGGCTTTGGCGCAAGCGTTGTTTGATGATGAACGCAACATGATCCGTATTGATATGTCCGAA
TATATGGAGAAGCATACTGTGGCCCGGCTGATCGGCGCCCCACCTGGTTATGTAGGTTACGATGAGGGAGGCCAGCTTAC
CGAAGCGGTACGTCGGAAACCTTACTCAGTCATTCTTTTTGATGAAATTGAAAAGGCCCATCACGATGTCTTTAACATCA
TGTTACAGATTCTAGATGATGGAAGGTTAACAGACGGCCAGGGCCGCACCATTGACTTTAAAAACACCGTAATTATTATG
ACTTCCAATATTGGCAGCCATGAGATCCTGGAATTCCAAAGAAAAGGTGACGGGGACTACCGGCAGATGAAAAAGGCGGT
AACCGATTTGCTGCAACGGCATTTTCGGCCGGAGTTTCTCAACCGGGTGGATGAAACAGTGGTATTCCACGCCCTGGAGC
CAAAACATATGCAACAAATCACTACGTTAATGCTGGAACGACTGGCCCGGCGTATTAAAGATACGGCTCGTATTGAGTTA
ACCTGGTCCGATAGTGCTGTGGTCTACCTGGCCCGTAAGGGATATGAACCCAGCTTTGGAGCCCGTCCCTTAAAGCGGCT
TATTCAGCAGGAAGTAGAAACACCGCTGAGCCGTATGATGGTGAAAGGAGATGTTATCCCCGGTAATACCGTTCATATTG
AGGCCAGCGGGGAACAGCTTGATTTGACAATAAAATAA

Protein sequence :
MEFNRYTQKSREAVAAAQNLAAQWHHQEINGKHLLMALLTQEGGLTPRFLEHAGVNVGVLQNLVQGLLRKAPAVHGYEGA
LRLGTGLARVFTRAEKEAGDMKDQYISVEHLLLALLEEGENELKEVFRQVGLSRETLLNSLRAIRGNQQVTSENPEETYE
ALEKYGRDLTRLAKEGKLDPVIGRDDEIRRTVEILSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDIPEGLKNKRVIA
LDMGALIAGAKYRGEFEERLKAVLKEVQRSNGGIILFIDELHTVVGAGAAEGAMDAGNLLKPMLARGELRAIGATTLDEY
RKHVEKDAALERRFQPVMVNPPTVEDTISILRGLKERYEIHHGVRIKDSALVAAATLSDRYISDRFLPDKAIDLMDEAAA
RLRTEIDSMPTALDEITRRIMRLEIEEAALKKEKDPISQERLEKLQEQLANLRSEADVMRTQWEVEKQAISRVRQLKKEI
EETKLAIERAEREYDLNRMAELTYGKLPELEKKLKSEEELLAGKEKHHRLLKEEVDEEDIARVVSRWTGIPLEKLMEGEK
EKLIHLDELLHRRVIGQHEAVQAVADAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELARALAQALFDDERNMIRIDMSE
YMEKHTVARLIGAPPGYVGYDEGGQLTEAVRRKPYSVILFDEIEKAHHDVFNIMLQILDDGRLTDGQGRTIDFKNTVIIM
TSNIGSHEILEFQRKGDGDYRQMKKAVTDLLQRHFRPEFLNRVDETVVFHALEPKHMQQITTLMLERLARRIKDTARIEL
TWSDSAVVYLARKGYEPSFGARPLKRLIQQEVETPLSRMMVKGDVIPGNTVHIEASGEQLDLTIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-163 52
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-99 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desca_0171 YP_004495987.1 ATP-dependent chaperone ClpB VFG2076 Protein 1e-112 41