Gene Information

Name : Desca_1696 (Desca_1696)
Accession : YP_004497456.1
Strain : Desulfotomaculum carboxydivorans CO-1-SRB
Genome accession: NC_015565
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1818610 - 1820361 bp
Length : 1752 bp
Strand : -
Note : TIGRFAM: Pyruvate kinase; KEGG: drm:Dred_2312 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PEP-utilising enzyme, mobile domain

DNA sequence :
ATGAGACGTACCAAAATTGTTTGCACTATCGGGCCTGCCAGTGAAAATGTGGAAACCTTAAAGAAAATGATGTTGGCTGG
CATGAACGTAGCAAGACTAAACTTTTCTCATGGCACCCACGAAGACCATGGTCGGAGAATAAAAGCCATTCGCCAAGCTG
CCGCTGAAGTGGGCAAAAATATTGCCATTATGCTGGATACCAAAGGACCGGAAATCCGGTTAAAGACCTTTGCCAATCCA
CCGGTAACGTTGGAACAAGGACAACGTTTTACCCTGACCACCCGAGATATTGTGGGTGATAACACCATTGTTGCTGTTAC
CTATAGTGATTTACCCAATGATGTAAAACCCGGTAGCCGGATAGCCATTGCTGACGGCTTAATTGAATTGGAAGTGGAGT
CGGTGGACGGGCCGGATGTACATTGCCGGGTGATCAACGGAGGCAAACTTTCCAACCAAAAGGGTGTAAACCTACCGGGC
GTCAACGTTAACCTGCCTTCTCTCACCGAAAGGGATATTGCCGATATTAAATTCGGGTTGGAACAAGGCGTCGATTTTAT
CGCTGCCTCCTTTATTCGTAAAGCCTCTGATGTTTTGGCCATTCGACAAATTGTAGAAGAGTACGGGGCAGAAGTGGACA
TCATTGCTAAAATTGAAAGCCGTCAGGGTGTTGATAATTTAGCGGATATAATTAATGTTGCTGATGGTATTATGGTGGCC
CGGGGTGATTTGGGAGTGGAGATCCCCGCTGAAGAAGTCCCGGTGCTACAAAAAACTATGATTGAAATGTGTAACATGGC
GGGGAAACCGGTAATTACCGCCACCCAAATGTTGGAATCCATGACCCAGAACCCCAGACCCACCAGGGCTGAAGCCAGTG
ATGTGGCCAACGCCATTTTCGACGGTAGTGACGCCATTATGCTGTCCGGTGAAACTGCCGCCGGTAAGTACCCGGTCCAG
GCAGTGGAGACCATGGCTCGCATTGCCCAGCGAGCCGAACTGGCCCTGGATTTTGATGAGCTTTTAGAAACTCGCGGGGC
AGCCATCGAGAGAACGGTTACCGACGGAATCAGCCATGCGGTTTGTACCATTGCCAAGGAACTGGGTGTAAGCGCCATTA
TTACAGCCACTGCCAGCGGGCATACAGCCAGGATGATTGCCAAATACCGGCCTAAAGCGCCTATCATTGCCGTTACACCA
AGGGCCAAGGTATTACGTAAAATGGCCCTGGTCTGGGGAGTCGAACCGCTTTTGATGGCTGACCTCACCGGCACAGATGA
AATGATTGCCGGTTCGGTGGAGGTGGCCTTGGCGGCAGGACTGATTTCCGCCGGCGACCTGGTTGTGATTACTGCCGGTG
TGCCGGTGGGTGTGCATGGTACCACTAACATGATGAAGGTACATACCGTGGGTACCCTGCTGGCCAGAGGCACCGGTATC
GGCCAGCGGGCGGTAACAGGGAAGGCCAGGGTCTGCCGCACCCTGAAGGATGCTTTGGATAAAGTGCAGCCAGGCGATAT
TTTGATTACCCATGCCACTGACCGTGACTTTGTCCCGGCCATGGAAAAAGCCGCTGCCGTCATTACCGAAGAGGGCGGTT
TAACCTCCCATGCAGCCATTGTTGGACTGGAATTTGGTATCCCGGTTATTGTGGGAGTGGAAAATGCCACCGACATTTTA
CCCGATGATGAGATTATTACCGTGGACGGGCAGCGGGGTCTGGTATACGGTGGCGTGGCCAGGGTACTGTAG

Protein sequence :
MRRTKIVCTIGPASENVETLKKMMLAGMNVARLNFSHGTHEDHGRRIKAIRQAAAEVGKNIAIMLDTKGPEIRLKTFANP
PVTLEQGQRFTLTTRDIVGDNTIVAVTYSDLPNDVKPGSRIAIADGLIELEVESVDGPDVHCRVINGGKLSNQKGVNLPG
VNVNLPSLTERDIADIKFGLEQGVDFIAASFIRKASDVLAIRQIVEEYGAEVDIIAKIESRQGVDNLADIINVADGIMVA
RGDLGVEIPAEEVPVLQKTMIEMCNMAGKPVITATQMLESMTQNPRPTRAEASDVANAIFDGSDAIMLSGETAAGKYPVQ
AVETMARIAQRAELALDFDELLETRGAAIERTVTDGISHAVCTIAKELGVSAIITATASGHTARMIAKYRPKAPIIAVTP
RAKVLRKMALVWGVEPLLMADLTGTDEMIAGSVEVALAAGLISAGDLVVITAGVPVGVHGTTNMMKVHTVGTLLARGTGI
GQRAVTGKARVCRTLKDALDKVQPGDILITHATDRDFVPAMEKAAAVITEEGGLTSHAAIVGLEFGIPVIVGVENATDIL
PDDEIITVDGQRGLVYGGVARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-103 50
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-103 50
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-103 50
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-103 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desca_1696 YP_004497456.1 pyruvate kinase VFG0479 Protein 7e-104 50