Gene Information

Name : Desca_0123 (Desca_0123)
Accession : YP_004495939.1
Strain : Desulfotomaculum carboxydivorans CO-1-SRB
Genome accession: NC_015565
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 126584 - 128317 bp
Length : 1734 bp
Strand : +
Note : TIGRFAM: Pyruvate kinase; KEGG: dhd:Dhaf_2755 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PEP-utilising enzyme, mobile domain

DNA sequence :
ATGAGAAAAACAAAAATTATTTGTACCATCGGGCCGGCCAGTGAAAGCGCGGAACAGGTACAGCGGCTGTTGGCTGCCGG
AATGGATGTGGCGAGGCTGAATTTTTCCCATGGCACCCACGAAGAACACGGCAGACGCATCTCCACCCTCCGGGAAGAGG
CTGCCAAATTGGGTAAGCATTTGGCCATTATTCTTGATACCAAAGGGCCTGAAATCCGTACAAGAATGGTTCCTGAACAG
GGTATGTATCTCTGTAGCGGTGACACCTTTATACTGGACACCGATCCCGAACTCGGTTCCCGAGAAAGGGTGGGCATTAC
TTACCGAGACCTGTGGCAGGAGGTGGTCCCGGGAACCCGGATTTTAATTGATGACGGGCAAATTGAACTGGAGGTCACCG
CTGTGCAGCAGGAGCGGATCACTACCGTGGTGCGCAATGGCGGGCTCCTGAAGTCCCAAAAGGGAGTCAACATCCCCGGA
GTTTCCATTCAACTGCCTGCCGTTACCGAAAAAGACATTGCGGACATCCGGTTCGGGCTTTCCCAGGGTATTGATTTCAT
TGCCGCGTCCTTTGTCCGCAAAGCGGCCGATATTCTGGCGGTACGCCGGATCGTTGAAGAGGCGGGTGCCGGTGTGCATA
TCATTGCCAAAATTGAGAACAGAGAAGGGCTGCAAAACCTCGATGCCATTTTACAAGTGGCCGATGGGCTGATGGTAGCC
CGTGGGGACCTCGGGGTGGAGATTCCGGCTGAGGAAGTGCCCATTGCCCAAAAAGAAATGATCAATAAATGCAATCTTCT
GGGCAAGCCGGTGATCGTTGCCACACAAATGTTGGACTCTATGATTCGTCAGCCCCGCCCCACCCGGGCCGAAGCCAGCG
ATGTAGCCAACGCCATTTTAGACGGGGCCGACGCCATCATGTTATCCGGCGAAACCGCTGCCGGTAAGTTTCCGGTGGAA
GCGGTAAAAATGATGGATAAAATCGCCAGACGTACAGAAACTATACTGTCGAACAAAAGCAGAGAGAGAAACCCTCACAT
TAATGTGACGGAAGCAATCAGTCACGCCAGCTGTACCATTGCAGAAGATCTCAATGCAGCGGCCATATTGACGCCCACTC
ATTCCGGGCTGACTGCCAGGATGATTTCCAAATACCGTCCCCGGTGCCCCATTGTGGCAGCTACACCCTTTGCAGGGACG
GCCCGGCGGTTGGCCCTGCAGTGGGGGGTGCAACCGCTGCTGGTTCCGGAAAGCGCCGGTACGGACCAGGTGATGTCGGT
GGCAGTGACTACGGCTCTGCAGCACAACCTGGTGCAAACCGGTGATGTGGTGGTGATTACCGCCGGTGTCCCCGCCGGTC
AAGCAGGAACCACCAACATGATCAAGATCCAGGTTGTGGGTAATATTTTAACCAGGGGAGCCGGTATCGGCCGTCAGGCT
TACTCGGGGACTGCCCGGAAGATCACCTCTCCTGAAACGGACACCTTCAACAACGGGGATGTCCTGGTGGCAGCTGCCAT
TGATGTCGATTTTATGTCACTGGTGGCCCGGGCCGGGGCGCTGGTTGTTGAGGAGGGCGGTTTAACATCCCACGCTGCCA
TTGCGGCCCTGCATTATGGTATTCCGGCGGTGGTAGGTGCGGCAGAGGCTTTAATAAAAATTTCCGATGGGCAGACCGTT
ACGGTGGACGCCCTCTCGGGGGTGGTTTACGAAGGTTCTGTAGCCATTCTATAG

Protein sequence :
MRKTKIICTIGPASESAEQVQRLLAAGMDVARLNFSHGTHEEHGRRISTLREEAAKLGKHLAIILDTKGPEIRTRMVPEQ
GMYLCSGDTFILDTDPELGSRERVGITYRDLWQEVVPGTRILIDDGQIELEVTAVQQERITTVVRNGGLLKSQKGVNIPG
VSIQLPAVTEKDIADIRFGLSQGIDFIAASFVRKAADILAVRRIVEEAGAGVHIIAKIENREGLQNLDAILQVADGLMVA
RGDLGVEIPAEEVPIAQKEMINKCNLLGKPVIVATQMLDSMIRQPRPTRAEASDVANAILDGADAIMLSGETAAGKFPVE
AVKMMDKIARRTETILSNKSRERNPHINVTEAISHASCTIAEDLNAAAILTPTHSGLTARMISKYRPRCPIVAATPFAGT
ARRLALQWGVQPLLVPESAGTDQVMSVAVTTALQHNLVQTGDVVVITAGVPAGQAGTTNMIKIQVVGNILTRGAGIGRQA
YSGTARKITSPETDTFNNGDVLVAAAIDVDFMSLVARAGALVVEEGGLTSHAAIAALHYGIPAVVGAAEALIKISDGQTV
TVDALSGVVYEGSVAIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-102 50
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-102 50
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-102 50
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-101 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desca_0123 YP_004495939.1 pyruvate kinase VFG0479 Protein 3e-102 50