Gene Information

Name : Desca_1062 (Desca_1062)
Accession : YP_004496844.1
Strain : Desulfotomaculum carboxydivorans CO-1-SRB
Genome accession: NC_015565
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 1183779 - 1185965 bp
Length : 2187 bp
Strand : -
Note : TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: tjr:TherJR_0444 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPa

DNA sequence :
ATGAGTAGCGCCGCTTTTCTGGAATTCCGCCTGGAAGGTTTATCCTGCGCTGATTGCGCCGCCAAATTGGAGCGTAACAT
TGCTGCTTTACCCGGCGTAGAACAGGCCAAATTGAATTTTGCTGCAGCCAAACTTACGGTTCGCGGTGACGTACAAGCAA
GCCTGATTATTGATGAGGCCAGGCGGGACGGTGTCCGGGCTATTCCGGCCCACCAAGACCGGGAGGCGGACCAGATAGCA
TTCTGGAAAAAACACCATAGGGCCATTTTCAGTGGTCTTGCCGGTATCCTGGTGGCTACCGGGTGGTTGGTTCATTATGC
CTTGGGTATGGAAAGTTGGGCCAAGCTGTTATACACAGCCACTATAGCCGTGGGAGGCTATGCTGTAGGCAAAAAAGCTT
TAGTATCCTTAGGCCGCCACCGGTTGGATATGAACGTTTTAATGAGTATCGCGGTGATCGGAGCCGTCTTAATTGGAGAA
TGGAGCGAGGGTGCCACGGTAGCCTTCTTATTCTCGGTCAGTGAAGCCTTAGAATCCTACACCATGGATAAAGCCCGCAA
CTCCATTCGTAACTTAATGAATCTGGCCCCGGATACGGCGATAGTCATCAGGAACGGCCAGGAAATCCAATTGCCGGTCA
AAGACGTGATCATCGGGGATATGCTGGTGGTACGCCCCGGCGAGAAAATTGCTATGGACGGCATTATTACTAATGGACAT
TCATCCATTAACCAGGCCACCATTACCGGGGAATCAGTACCGGTGGATCGTGGCCCGGGAGGCGAAGTCTATGCCGGTAC
CATCAACGGCGAAGGCAGTTTAATGGTCAGGGTGACTAAACTAGTGCAGGATAACACCATCTCTCGGATCATCCACTTGG
TGGAAGAAGCCCAAGGCCAGCGGGCTCCGTCCCAGGCCTTTGTTGACCGCTTTGCCGCCGTCTATACGCCGGTGGTGATA
ACTTTGGCGGCATTAATTGTGGTAATTCCTCCCCTGCTTTTAAACCAGCCCTGGGCACCATGGATTTACCGGGGTTTAGC
CCTGCTGGTGGTGGCCTGTCCCTGTGCGCTGGTTATCTCAACGCCGGTGGCCATCGTTTCGGCCATTGGCAATGCCGCCA
GGCACGGTGTGTTAATCAAAGGGGGCATTCATCTAGAAGAAGTAAGCCGCCTTAGGGCCTTAGCCTTTGATAAAACCGGC
ACCTTGACCAAGGGTTTACCGGAGGTCACTCAGGTGATACCTGCTGACCATATTAGCGAAAGCGAATTACTTACTATAGC
CGGGGCGGTGGAACATCATTCAGAGCACCCCCTGGCTCGGGCTATCGTGGCTAAAACCAGGGATATAAATATTTACCCAA
CCCCGGCGGAAAACTTCCAGGCCTTAACTGGGCTAGGCGCCCGGGCCACGGTAAATGGACAAAATATTCTGGTGGGTAGC
CCGCGTTTACTCGAACAAAACGGTATTAATATTGCCGGGTGGCAGGAAGCACTGGCCTCCCTTTTCTCCCTGGGTAACAC
AGTTGTTATGGTGGCCAGAGAAAAAGAAGTGTTGGGTTGTATTGGGTTGGCTGATCGGGTTCGCCCCATGGCCGCAGATT
CTGTGGCTAAACTTAGTAAATTAGGTATATCTCCGCTGATTATGTTGACCGGTGATAACCGGCAGACCGCTGAAGTGATT
GCAGCCCAGGCCGGAATTGATGATTTCCGGGCTAACTTGCTACCTCAGGATAAAGTTGCAGAAATTAAGAAGATGCGCCA
AGAACTTGGTTTTATCGGTATGGTGGGTGATGGTATTAACGATGCCCCGGCCCTGGCAGCAGCCAACGTCGGTATCGCCA
TGGGCGGGGCCGGTAGTGATGCTGCCCTGGAAACTGCTGACCTGGTGTTAATGGGAGATGATTTAAGTAAACTTCCCTTT
ACCGTTCGTATGGCTCGGTCTGCCATGCAAGTAATTAAACAGAATATTACCTTTGCCATAGGGATTAAGCTGCTGGCTGT
TTTAGCAGTATTTCCCGGTTGGTTGACTCTATGGCTGGCTATACTGGCTGATATGGGGGCAACCATTATGGTAACCCTCA
ACAGCATCAGATTAGTGGGCATTAAACCGGACGGCGGGTCAGATTTTACCATTGATCCTGTCCCTGGTTGTGGTGGTAAT
AAGCCTGATCCGGCCACAGGTGGCTGA

Protein sequence :
MSSAAFLEFRLEGLSCADCAAKLERNIAALPGVEQAKLNFAAAKLTVRGDVQASLIIDEARRDGVRAIPAHQDREADQIA
FWKKHHRAIFSGLAGILVATGWLVHYALGMESWAKLLYTATIAVGGYAVGKKALVSLGRHRLDMNVLMSIAVIGAVLIGE
WSEGATVAFLFSVSEALESYTMDKARNSIRNLMNLAPDTAIVIRNGQEIQLPVKDVIIGDMLVVRPGEKIAMDGIITNGH
SSINQATITGESVPVDRGPGGEVYAGTINGEGSLMVRVTKLVQDNTISRIIHLVEEAQGQRAPSQAFVDRFAAVYTPVVI
TLAALIVVIPPLLLNQPWAPWIYRGLALLVVACPCALVISTPVAIVSAIGNAARHGVLIKGGIHLEEVSRLRALAFDKTG
TLTKGLPEVTQVIPADHISESELLTIAGAVEHHSEHPLARAIVAKTRDINIYPTPAENFQALTGLGARATVNGQNILVGS
PRLLEQNGINIAGWQEALASLFSLGNTVVMVAREKEVLGCIGLADRVRPMAADSVAKLSKLGISPLIMLTGDNRQTAEVI
AAQAGIDDFRANLLPQDKVAEIKKMRQELGFIGMVGDGINDAPALAAANVGIAMGGAGSDAALETADLVLMGDDLSKLPF
TVRMARSAMQVIKQNITFAIGIKLLAVLAVFPGWLTLWLAILADMGATIMVTLNSIRLVGIKPDGGSDFTIDPVPGCGGN
KPDPATGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-170 51
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-170 51
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-166 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desca_1062 YP_004496844.1 heavy metal translocating P-type ATPase BAC0298 Protein 8e-105 48
Desca_1062 YP_004496844.1 heavy metal translocating P-type ATPase BAC0092 Protein 7e-101 43
Desca_1062 YP_004496844.1 heavy metal translocating P-type ATPase BAC0100 Protein 1e-76 42