Gene Information

Name : Mar181_2537 (Mar181_2537)
Accession : YP_004482487.1
Strain : Marinomonas posidonica IVIA-Po-181
Genome accession: NC_015559
Putative virulence/resistance : Virulence
Product : (2,3-dihydroxybenzoyl)adenylate synthase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 2805729 - 2807399 bp
Length : 1671 bp
Strand : +
Note : KEGG: sen:SACE_2694 2,3-dihydroxybenzoate-AMP ligase; PFAM: AMP-dependent synthetase/ligase

DNA sequence : 
ATGAATGCGGCATTCGATGGACTTACTCCGTGGCCAGAAGAATTGGCAGAAACCTATTGCAAAGGCGGTTATTGGCAAAA
CCAAAACCTAGCCAGCTGGTTTGCTGAGAAAGTCTCTAATAAAGAAAACATTGTTCTCAGTGGACTGGGGATAGATGGTA
AGCCTCAGGACCTCACAGGGAAAGAATTACACCTTTGCGTGCAGGAACTTGCGCAAGGCTTGGCGAAACTAGACATTCAA
CCAAGTGAGAAAGTGGTATTACAAATGGGTAATACCAATAGCTTTGTTATTACCTTGTTTGCACTGTTTGAACTAGGTGC
TATTCCAGTGATGGCACTGCCTGGCCATAGGTATAGAGAAATAGAACATTTCCTTAACCTAACCAAGGCTCGTACATGGA
TTGCAGGAGACATTGAAGAAAACTCTCCTATTCCAGACTTGGCCGTTAAGCTAAAAGAAGGTGTACCTAGCTTACAAAAT
ATCATTCTTGATAAACAAGATACTGGCTCGTTTCACTCATTAGGGTCCTTACTAAAAAAAGGGAATAAAAAGTTTGAAAG
CACCAATCTCGGTCATGCAACTGACCCAGCTGGAATAGCTGTATTGTTATGCTCAGGTGGCACAACTGGATTACCTAAGC
TGATTCCTCGAACGCATCGTGATTATCTATTCAATGCAAAAGCCAGCGCTGAAGTATGTGAATTAGATGAAAATGATGGC
TATTTAGTCGCATTACCAGCAGGACACAACTTCCCATTGGCTTGCCCGGGGATTTTAGGCGCCTTCGAACAAGGTGCTAA
AGTGGTTATGTGCCCTTCTCCTAGCCCAGACATTGCCTACCAATGGATCACAGATACCAATGCCACTGTTACCGCCCTCG
TCCCTCCCCTAGTTCGAGTATGGCTACAAAATGCTGAGCTTGGCTTTAAAGCCCCAAGCACATTGAGAATGCTGCAAGTA
GGTGGATCACGCCTAGATGCAGATTTAGCCCAATGTATTCCGAATAAGTTAAGCTGCAAATTACAGCAAGTATTCGGCAT
GGCCGAAGGCCTATTAAACTTCACTCGCAGTAAAGACCCAGACCTTTTGGTACAAAAAACACAAGGTCGACCTTTGTCTG
AGCTGGATGAAATTCGAATAGTTGATAGCCAAGGACAAGACGTACCCAATGGCCAACGAGGCGAACTTTGGACAAGAGGC
CCTTACACTTTAAGAGGTTATTACAAGGACCCAAAAGCAAATGATTCTTCATTTTCGGCAGATGGTTATTACAAATCAGG
CGACCTTGTCCGCCGTTTAAGTTCTGGTCACCTTATTGTTGAGGGACGTATAAAAGAAGTCATTCGTAGAGGCGCAGAGA
CCATACCAGCAGAATCTCTCGAGACGCACTTAAGCCTACATTCAGAGATTCAAGCCGCCGCGGTGATTGGACTACCTTGC
GAACGTTTAGGACAGCAAGTATGCGCTGTACTGGTTAACAAAGAAGAGACAGATCTAACACTGACGCTAAATGAAGTCCG
TCATTTCTTAATTGAAGAAGGCGTTGCGCATTTTATGCTGCCCGATTCAATCGAATATGTGCCTGAACTTCCTCTTACTG
CTGTAGGTAAAGTGGCCTACCAACAATTGATCTCAAAATTTTCTCCCCCTTCACCTGAGACCACATATTAA

Protein sequence : 
MNAAFDGLTPWPEELAETYCKGGYWQNQNLASWFAEKVSNKENIVLSGLGIDGKPQDLTGKELHLCVQELAQGLAKLDIQ
PSEKVVLQMGNTNSFVITLFALFELGAIPVMALPGHRYREIEHFLNLTKARTWIAGDIEENSPIPDLAVKLKEGVPSLQN
IILDKQDTGSFHSLGSLLKKGNKKFESTNLGHATDPAGIAVLLCSGGTTGLPKLIPRTHRDYLFNAKASAEVCELDENDG
YLVALPAGHNFPLACPGILGAFEQGAKVVMCPSPSPDIAYQWITDTNATVTALVPPLVRVWLQNAELGFKAPSTLRMLQV
GGSRLDADLAQCIPNKLSCKLQQVFGMAEGLLNFTRSKDPDLLVQKTQGRPLSELDEIRIVDSQGQDVPNGQRGELWTRG
PYTLRGYYKDPKANDSSFSADGYYKSGDLVRRLSSGHLIVEGRIKEVIRRGAETIPAESLETHLSLHSEIQAAAVIGLPC
ERLGQQVCAVLVNKEETDLTLTLNEVRHFLIEEGVAHFMLPDSIEYVPELPLTAVGKVAYQQLISKFSPPSPETTY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-83 41
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-83 41
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-82 41
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-82 41
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-82 41
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-82 41
ybtE CAA21394.1 - Virulence HPI Protein 2e-82 41
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-82 41
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-82 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mar181_2537 YP_004482487.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG1817 Protein 4e-100 43
Mar181_2537 YP_004482487.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0168 Protein 4e-91 41