Gene Information

Name : Psefu_3770 (Psefu_3770)
Accession : YP_004475821.1
Strain : Pseudomonas fulva 12-X
Genome accession: NC_015556
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 4065145 - 4067094 bp
Length : 1950 bp
Strand : -
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: pst:PSPTO_2478 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim domain

DNA sequence :
ATGCGTCTGTTTCTCTGCGAAAAGCCCTCCCAAGCCAAAGACATCGCCAGCGTGCTTGGTGCCACGCGGCGTGGCGACGG
CTGCTGGCTGGGCAACGGCGTGACGGTCACCTGGTGCATCGGCCATTTGCTCGAAACCGCGCCACCGGATGCCTACGACG
CGCGCTACAAGCGCTGGGTGCTGGACGACCTGCCCATCGTCCCGCAGCAGTGGAAAATGCGCGTCAAAGCCAATACCGCC
GCTCAGTTCAAGGCCATCAAGCGCCTGCTTGGCGAGGCCAGCGAGCTGGTGATCGCCACCGACGCGGATCGCGAGGGCGA
GATGATCGCTCGCGAGTTGCTCGAGCATTGCCGCTACCGCGGGCCGATCCAGCGTTTGTGGCTGTCGGCGCTGGACGACG
CCTCGATCCGCAAGGCCCTGGCGGCGCTCAAACCGGGCGCCAGCACCTACAACCTCTATCAGTCGGCGCTCGGTCGCTCG
CGGGCCGACTGGCTGATCGGCATGAACATGAGCCGCCTGTTCACCCTGCTGGGGCGCAAGTCCGGTTATCAGGGCGTGCT
GCCGGTCGGCCGCGTGCAGACGCCGACCCTGCGCCTGGTGGTCGACCGCGACCGCAGCATCGCCGACTTCGTGCCGGTGC
CGTTCTGGGCCATCGACGTGACGCTCGACGGCAATGGCATTCCGTTTACCGCCGTGTGGCGCGCGCCCCAGGACGATTGC
GACGAGCAGGGCCGCTGCCTGAAGCAGGAAGTGGCGCAGCGCGCCGCCGAGGCCATGCAGGGCGCCGAGCATGCCGTGCT
GGAGAAGTTGAAGACCGAGCGCATGCGTGAGGCGCCGCCGTTGCTGTTCGACCTCGGTACGCTGCAGCAGGTGTGCTCGA
AGAAGCTCGGCCTGGGCGCCCAGGAAACCCTGGACATCGCCCAGAAACTCTACGAGACAGACAAGCTGATCACCTATCCG
CGCAGCGATTGCGGTTACCTGCCGCTCAGCCAGCACGCCGAGGCACCGGCCATTTTAGCCGCGCTGGGGCAGGCCGATCC
GACATTGCGTGAAGTGCTGGCGCATACCCAGACGCAGCGCCGCTCGCGGGCCTGGAACGATGCCAAGGTCAGCGCCCACC
ACGGCATCATCCCGACCCTGGCGGCTGGAGGGCTGACTCGACTGAGCGGCCGGCCGCGTGCGGTTTATGAACTGATCCGT
GCCCGCTATCTGGCGCAGTTTCTGCCCAACCACGAATACGATCGCACCCAGGCCGACTTCGACTGCGCCGGCCATGACCT
GCGTGCGGTCGGCAAACAGATCGTCGAGCCGGGCTGGAAACGCGCGCTGCCCGAAGCCCTGGCTCCGAGCAAGGGCCGTG
AGGCGCCTGCGCCCCAGGCCTTGCCCGCACTGCATGAAGGCCAGACGTGCGCGGTGCGTGAAGTGACGCTCAAGGATCAA
TTCACTCAGCCGCCCAAGCCGTTCACCGAGGGCGACCTAATCCAGGCCATGAAGAACGTCGCGCGGCTGGTCGAGGACCC
GCTTCTGAAGCAGAAGCTCAAGGACACCACTGGCATCGGCACCGAAGCCACCCGCGCCGGCATCATCCAGGGCCTGCTCG
ACCGCGGTTACCTGACCAAGCAGGGCAAGACCCTGGCCGCCACCTCGGCAGCCTTCGGCCTGATCGATGCGGTGCCCCGC
GCTATCGCCGACCCCGGCACCACGGCGATCTGGGAGCAGGCGCTGGATATGGTGCAGAGCGGCGAGATGCCCCTGGACGA
ATTCGTTGCCAAGCAATCTGCTTGGATGGCCAGGCAGATCGAGCGCTGCCGTGGCCTGCAACTGACCATCAGCGGCCCGC
CGCCGGGTGGCAGGCCGGCTTGGAAGGGCAAGCGAAAAGGCGCCTCGCGCAAGAAGGCTGCATCGGCCAAGCGTGCAGGT
GCTAGCGCCGCAGGGGGCAGATCTAAGTAG

Protein sequence :
MRLFLCEKPSQAKDIASVLGATRRGDGCWLGNGVTVTWCIGHLLETAPPDAYDARYKRWVLDDLPIVPQQWKMRVKANTA
AQFKAIKRLLGEASELVIATDADREGEMIARELLEHCRYRGPIQRLWLSALDDASIRKALAALKPGASTYNLYQSALGRS
RADWLIGMNMSRLFTLLGRKSGYQGVLPVGRVQTPTLRLVVDRDRSIADFVPVPFWAIDVTLDGNGIPFTAVWRAPQDDC
DEQGRCLKQEVAQRAAEAMQGAEHAVLEKLKTERMREAPPLLFDLGTLQQVCSKKLGLGAQETLDIAQKLYETDKLITYP
RSDCGYLPLSQHAEAPAILAALGQADPTLREVLAHTQTQRRSRAWNDAKVSAHHGIIPTLAAGGLTRLSGRPRAVYELIR
ARYLAQFLPNHEYDRTQADFDCAGHDLRAVGKQIVEPGWKRALPEALAPSKGREAPAPQALPALHEGQTCAVREVTLKDQ
FTQPPKPFTEGDLIQAMKNVARLVEDPLLKQKLKDTTGIGTEATRAGIIQGLLDRGYLTKQGKTLAATSAAFGLIDAVPR
AIADPGTTAIWEQALDMVQSGEMPLDEFVAKQSAWMARQIERCRGLQLTISGPPPGGRPAWKGKRKGASRKKAASAKRAG
ASAAGGRSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 63
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 61
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 61
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-155 52
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-155 52
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-155 52
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 9e-152 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-145 49
topB AAW83109.1 TopB Not tested GGI Protein 9e-114 43