Gene Information

Name : Thexy_0635 (Thexy_0635)
Accession : YP_004470358.1
Strain : Thermoanaerobacterium xylanolyticum LX-11
Genome accession: NC_015555
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 677190 - 678941 bp
Length : 1752 bp
Strand : +
Note : TIGRFAM: Pyruvate kinase; KEGG: ttm:Tthe_0771 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PEP-utilising enzyme, mobile domain

DNA sequence :
ATGCGTAGAACTAAGATAATATGTACGATTGGTCCTGCCAGTGAAAAGTATGAGATATTGAGAGAGCTTATAGAAAGTGG
TCTTAATATCTGCAGACTGAATTTTTCACATGGTGACCATGAAGAGCATGGAAGCAGGATAGATAATATTATAAAGATTA
GAGAAGAGCTTAATCTGCCTATAGCAATTATGCTTGATACAAAAGGACCTGAAATAAGGACTGGCAAATTTAAAGGCGGT
ATTGCAGAGCTAAAAGAAGGTCAGACATTTACGGTGACATCAAGGGAAATTGAAGGAGATAATACTATTTGCTCTGTTTC
ATACAAGGGGCTTCCTCAAGATGTGGGGAGAGGTTCTCGCATATTGATTGATGACGGGTTAGTATCATTGAAGGTCAATG
ACGTAAAAGGCGAAGATATAATATGCACTGTGGAGAATTCTGGTACAATAGGTGACCACAAAGGTGTAAATGTGCCTGGT
ACAAAGCTTAATTTGCCTGCTATAACGCAAAAAGATGTAGATGACATAGAGTTTGGAATAAAAAAAGGAATCGACATGAT
TGCAGCGTCTTTTGTTAGAAAAGCAGCGGATGTAATAGCTATAAGGAGATTGTTAGAAGACAATGACGCTGGTCATATAC
TTATTATATCAAAAATTGAAAATCGCGAAGGTGTGGAAAATATCGACGAAATAATTAAGGTTTCTGACGGCATAATGGTT
GCCCGCGGTGATTTAGGTGTTGAAATTCCTATAGAGGAAATACCTATAGTTCAGAAAAGGATAATTGAAAAATGCAATAA
AGCAGGTAAACCAGTTGTCACTGCTACCCAGATGCTTGATTCTATGATAAGAAATCCAAGGCCCACAAGGGCAGAGGTGA
CAGATGTGGCCAATGCCATATTGGACGGTACTGATGCGATAATGTTGTCTGGTGAAACAGCACAAGGCAAATATCCGGTA
GAAGCTTTTAAGACAATGTCAAAGATAGCTGAAAAAATTGAAACGTATATAAATTACAAAGAAAATTTAGATAAAAATGT
GGATTACAATATTTCTATGACAAACGCTATAAGCCATGCTACATGCACTACCGCAAGAGATATAGGTGCGACTGCCATTA
TTACATCTACAATATCAGGCTATACTGCTCGAATGGTGTCTAAGTATAGACCGTCAGCACCTATAATTGCAGTGACGCCA
AACAAAGATGTAGCAAGAAAGCTTAGCATCGTATGGGGTGTACATCCACTCATATCACAAGAAGTCAGCTCTACAGATGA
AATGATAGAAGTATCAGTAAATACGGCTTTAAGTGAAGGCTTAATTCGAAATGGCGATATTGTAGTAATATCGGCAGGAA
TACCTGTCGCGACTACAGGCACGACAAATATGTTGAAGGTTCATATTGTGGGAGATGTAATAGTAAAAGGCACAGGCATA
GGTACTAAATCCATAAGTGGTGTTGTTTCCATCATAAGAGATCCATACAAGGACAAAGATAAGTTCAGAGAAGGAGACAT
CATCGTTGCTCAAAAAACTGAAAGGGATTATATGCCTATAATTGAAAAGGCTTCGGCTATCATAACAGAAGAAGGCGGAC
TAACGTCACATGCTGCAATAGTTGGATTAAACTATGGATTGCCTGTCATTGTAGGATGTGAAGGAGTAACAGCTAAGCTA
AAAGATGGAATGACGGTAACTCTCGATACTGCCAGAGGATTGGTCTACAAAGGCATAGTGAATATAAAATAG

Protein sequence :
MRRTKIICTIGPASEKYEILRELIESGLNICRLNFSHGDHEEHGSRIDNIIKIREELNLPIAIMLDTKGPEIRTGKFKGG
IAELKEGQTFTVTSREIEGDNTICSVSYKGLPQDVGRGSRILIDDGLVSLKVNDVKGEDIICTVENSGTIGDHKGVNVPG
TKLNLPAITQKDVDDIEFGIKKGIDMIAASFVRKAADVIAIRRLLEDNDAGHILIISKIENREGVENIDEIIKVSDGIMV
ARGDLGVEIPIEEIPIVQKRIIEKCNKAGKPVVTATQMLDSMIRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPV
EAFKTMSKIAEKIETYINYKENLDKNVDYNISMTNAISHATCTTARDIGATAIITSTISGYTARMVSKYRPSAPIIAVTP
NKDVARKLSIVWGVHPLISQEVSSTDEMIEVSVNTALSEGLIRNGDIVVISAGIPVATTGTTNMLKVHIVGDVIVKGTGI
GTKSISGVVSIIRDPYKDKDKFREGDIIVAQKTERDYMPIIEKASAIITEEGGLTSHAAIVGLNYGLPVIVGCEGVTAKL
KDGMTVTLDTARGLVYKGIVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-95 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-94 49
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-95 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-95 49
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 6e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thexy_0635 YP_004470358.1 pyruvate kinase VFG0479 Protein 4e-95 49