Gene Information

Name : Mahau_0855 (Mahau_0855)
Accession : YP_004462875.1
Strain : Mahella australiensis 50-1 BON
Genome accession: NC_015520
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 895685 - 896992 bp
Length : 1308 bp
Strand : +
Note : COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR003593: IPR005714: IPR004100: IPR000194: IPR 020003; KEGG: cce:Ccel_2048 ATPase FliI/YscN; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+tran

DNA sequence :
GTGATATCGCTTGACAAGTATAAAGGGGCGATTAAAAATATTGACTCCATAGAATATAAGGGAGCGGTTTCACGTCTGAC
AGGTCTTACAATAGAGGCTGATGGGCCAGGTGTGGAAATAGGCCGTTTGTGCAAGATATTGTCACAGGATGGTTCGATTT
CTGCGATAGCTGAGGTTGTCGGTTTCAGAGAAGAACGTATGCTGCTTATGCCGCTAGGCAACGTTAAAGGCATAGGTCCA
GGCAGTACCGTCATTGCCATGAATACCTCACTTACGGTACCGGCAGGCCCCGGTTTATTAGGAAGGGTGCTGGACGGTTT
AGGGCGGCCTATGGATTCGGCAGGGCCGTTGGCTGCTGATATGTATTACGATGTGGAAAAAGATCCGCCTGACCCACTGA
CTCGCCAGCGCATATGCGAACCTATCGTATTAGGCATAAAAGCAATAGACGGCCTTCTCACGTGCGGATACGGGCAAAGG
ATGGGCGTATTTGCGGGCAGCGGTGTGGGTAAAAGCACGCTCATGGGCATGATGGCGCGTTATGCATCAGCGGATGTGAA
CGTGATAGCGCTGATAGGAGAGCGTGGCAGAGAAGTAAAGGAATTCATAGAAAAAGATCTGGGAGAGGGACTGGCCCGTT
CAGTGCTCGTAGTAGCCACATCAGATCAACCTCCCCTTATCAGGACCAAAGCTGCCTTTGTAGCTACCGCAATAGCTGAG
TACTTTAGAGATCAGGGATGCAACGTGTTATTGATGATGGATTCGCTTACAAGATTTGCTATGGCCCAGCGTGAGGTCGG
CTTGGCTATAGGCGAACCACCGGTATCGCGCGGTTATACGCCATCGGTATTTGCTACTATGCCAAGGCTGTTGGAACGAG
CAGGAACATCGGATAAAGGCAGCATTACCGGTATATATACCGTGCTGGTAGACGGCGATGATTTTAACGAACCTGTCACC
GATAACGCGCGTAGTATATTGGATGGCCATATAGTATTATCCAGAGAATTGGCTAACCGAAATCACTATCCACCTATAGA
TATACTGGCGAGCGTCAGCAGGGTTATGCCTGATGTCGTAACAGACAGGCATATGATGCTGGCATCTCAGATAAAAAAGA
TCATGGCTGTGTATAAGGGAGCTGAGGATCTTATAAATATAGGCGCTTATGTAAGAGGGAGCAGCCGGGATATAGACTAT
GCGATAGATCATATAGATGATATAAATGATTTTTTACAGCAGCTTGTGGGACAAGCCTTCAGTTTGCCAGAGATACTGTC
AATGATGGAAAATATTATAAAGGAATAG

Protein sequence :
MISLDKYKGAIKNIDSIEYKGAVSRLTGLTIEADGPGVEIGRLCKILSQDGSISAIAEVVGFREERMLLMPLGNVKGIGP
GSTVIAMNTSLTVPAGPGLLGRVLDGLGRPMDSAGPLAADMYYDVEKDPPDPLTRQRICEPIVLGIKAIDGLLTCGYGQR
MGVFAGSGVGKSTLMGMMARYASADVNVIALIGERGREVKEFIEKDLGEGLARSVLVVATSDQPPLIRTKAAFVATAIAE
YFRDQGCNVLLMMDSLTRFAMAQREVGLAIGEPPVSRGYTPSVFATMPRLLERAGTSDKGSITGIYTVLVDGDDFNEPVT
DNARSILDGHIVLSRELANRNHYPPIDILASVSRVMPDVVTDRHMMLASQIKKIMAVYKGAEDLINIGAYVRGSSRDIDY
AIDHIDDINDFLQQLVGQAFSLPEILSMMENIIKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-98 53
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 7e-75 53
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-75 53
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-75 53
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-75 53
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 8e-75 53
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-86 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-86 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-87 52
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-79 52
escN AAC38383.1 EscN Virulence LEE Protein 2e-80 52
escN AAC31513.1 L0034 Virulence LEE Protein 2e-80 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-79 52
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-80 52
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-79 52
escN AAK26715.1 EscN Virulence LEE Protein 3e-79 52
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-80 52
escN AAL57542.1 EscN Virulence LEE Protein 3e-79 52
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-80 52
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-79 52
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-80 52
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-78 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-86 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-87 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-87 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-87 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-87 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-87 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 8e-80 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-78 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-78 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-74 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-62 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-64 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-64 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-64 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 6e-63 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-75 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-69 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-69 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-70 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 8e-66 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 8e-61 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 8e-61 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-65 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-65 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-65 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-65 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-63 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 3e-97 57
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 5e-95 56
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 9e-95 55
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 6e-89 55
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 4e-75 53
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 1e-80 52
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 1e-80 52
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 5e-82 52
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 5e-89 49
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 5e-78 49
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 3e-63 44
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 1e-65 43
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 1e-67 42
Mahau_0855 YP_004462875.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 2e-70 42