Gene Information

Name : Mahau_2111 (Mahau_2111)
Accession : YP_004464105.1
Strain : Mahella australiensis 50-1 BON
Genome accession: NC_015520
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.99.3
Position : 2258580 - 2260055 bp
Length : 1476 bp
Strand : +
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: dds:Ddes_1981 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase (NAD+); PFAM: Aldehyde dehydrogenase

DNA sequence : 
ATGTCTAAGTTGATCGATGATAGTTACAAACTCTTTATTGACGGTAAATGGGTCGATGGAAAAGAAGGTAAGACTTATAA
AGAATATAATCCAGCCAACGGCGAATTATTAGCAACGTGTGCAGATGCTGGAAAAGAAGACGTAGATATGGCCGTAAACG
CGGCGTGGAAAGCGTTTGAAACATGGAAAGACGTAAGCCCTCAAGAACGTGCTAAGATGCTTCTTAAAATCGCCGATCTA
ATCGATGAAAATGCAGAAAAATTGGCTATGATAGAAACCCTAGACAATGGCAAACCTATACGTGAAACTTCCACTATAGA
TGTCCCTCTAAGTTCGGATCACTTCCGTTATTTTGCTTCAGCTATAAGAACAGAAGAAGGCCAAGCTGTAATGATCGATA
AAGACACCATGAGTATAATCTTAAGAGAGCCTATAGGCGTTGTAGGCCAGATAGTCCCATGGAACTTCCCGCTTTTAATG
GCGGCATGGAAGCTCGCTCCCGCACTGGCTGCCGGCGATTGCGTTGTATTTAAACCTTCTTCCGAAACATCTCTAAGCGC
GCTGGAGCTGGCCAAGCTCATGAGCGAAGTATTGCCTCCAGGAGTGATAAATGTCGTCACGGGTAAAGGTTCTACCACAG
GCAATTACATGCTTGAACACGAAGGCTTCCGCAAACTAGCTTTCACTGGTTCTACAGAGGTCGGTTACACTGTAGCTGAG
GCAGCAGCCAAAAAGCTTATTCCTTCCACATTAGAGCTGGGCGGCAAATCTGCCAATATTTACTTTGAAGATGCACCATG
GGAGAAAGCCATAGAAGGTTTACAGATAGGCATCCTATTTAACCAAGGCCAGGTCTGCTGCGCTGGCTCACGTGTATTTA
TCCAAGATTCCATATATGATAATTTCCTCGCTGACGCTATAGCAGCCTTCGAAAAAGTAAAGGTGGGCCTGCCGTGGGAA
AAAGATACACAAATGGGCTCACAGATCAATGAAAACCAGCTCAAAAAAATCCTTGCCTACATAGAGATAGGCAAAAAAGA
AGGTGCCAAAATAGCCGCAGGAGGCTACCGCATCACTGACAATGGTCTCGATAAAGGCTACTTTATAAAACCTACCATAC
TCATCGATGTCGATAATAAAATGAGAGTGGCCCAGGAAGAAATCTTTGGTCCAGTTGTATGCTTCATACGCTTCAAGGAC
GAAGATGAGGTTATTAAAATGGCAAATGATAGTGAATACGGCCTTGGCGGTGCCGTATGGACAAAGGATCTCAATCGCGC
TTTCCGCGTTGCTAGAGCTGTGGAAACCGGTAGGATGTGGGTAAACAATTACAACAACCTGCCTGCACACGCACCTTTTG
GCGGCTATAAAAAGTCTGGTATAGGACGTGAAACGCATAAGGTTATCCTTGAGCATTATACGCAGATGAAAAACATTTTT
ATCAGTTTCACCGAAAATAAAACAGGACTTTATTGA

Protein sequence : 
MSKLIDDSYKLFIDGKWVDGKEGKTYKEYNPANGELLATCADAGKEDVDMAVNAAWKAFETWKDVSPQERAKMLLKIADL
IDENAEKLAMIETLDNGKPIRETSTIDVPLSSDHFRYFASAIRTEEGQAVMIDKDTMSIILREPIGVVGQIVPWNFPLLM
AAWKLAPALAAGDCVVFKPSSETSLSALELAKLMSEVLPPGVINVVTGKGSTTGNYMLEHEGFRKLAFTGSTEVGYTVAE
AAAKKLIPSTLELGGKSANIYFEDAPWEKAIEGLQIGILFNQGQVCCAGSRVFIQDSIYDNFLADAIAAFEKVKVGLPWE
KDTQMGSQINENQLKKILAYIEIGKKEGAKIAAGGYRITDNGLDKGYFIKPTILIDVDNKMRVAQEEIFGPVVCFIRFKD
EDEVIKMANDSEYGLGGAVWTKDLNRAFRVARAVETGRMWVNNYNNLPAHAPFGGYKKSGIGRETHKVILEHYTQMKNIF
ISFTENKTGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-92 51
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-95 51
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-95 51
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-95 51
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-95 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mahau_2111 YP_004464105.1 aldehyde dehydrogenase VFG0082 Protein 4e-92 51