Gene Information

Name : Mahau_1398 (Mahau_1398)
Accession : YP_004463413.1
Strain : Mahella australiensis 50-1 BON
Genome accession: NC_015520
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1474314 - 1476065 bp
Length : 1752 bp
Strand : -
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR008279: IPR018209: IPR 001697; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFA

DNA sequence :
ATGCGTAAGACTAAGATAATATGCACTATAGGGCCGGCCAGCGACGATAAAGCGATATTCGAACGATTGATAGCACACGG
TACGAATGCCATACGGCTTAATTTTTCTCACGGCTCTTATGAGGAACACGGAAAGCGTATAGACATGGCAAAAGACGCCA
GGCGAAGCCATAATATACCGCTATCGATCATATTGGATACAAAAGGTCCGGAAATGCGATTGGGTAAATTTAAAATCGAG
CCCGTAGAACTAAGAGAAGGTCAGTCGTTCACGCTAGCCACAAGGGATATAGAGGGCGACAATTCTATAGTATCGGTAAA
TTACGCCGGTTTGACCAAAGATATTAAACAAGGCGATAAATTGCTATTAGATGACGGATTGATAGAGCTGAGGGTAAAAG
ATATCGAAGGTACAGATATCCATTGTACGGTCATGAATAGCGGCCTAATAAGCAGCAAAAAAAGTGTTAATGCTCCTGGT
ATATCTATACAGTTGCCTTCGGTGACTCAAAAAGATATAGACGATATTAAATTCGGCGTAGAGAAAGGCATAGATACCAT
AGCAGCTTCTTTCATACGTAGAGCCGAAGATGTATTGGAGATTAAAAGGATTCTCGAAGATAATAATGCCTATGATGTAC
AGATAATAGCTAAAATAGAGAATCAAGAGGGAATCAACAATCTGGATGATATAATGGCTGTGGCTGATGGTATAATGATA
GCAAGAGGAGACCTCGGCGTAGAGATACCTACAGAAGATGTTCCGGTAGTACAAAAGGCCATTATATCCAAGTGCCGTGA
TGCCGGTAAACCGGTCATAATAGCTACCCAAATGCTCGATTCCATGATACGTAATCCGCGGCCCACGCGAGCTGAGGCCA
CCGATGTGGCCAACGCTATATACGAGGGGGCCGACGCTATAATGTTATCGGGAGAAACAGCATCAGGTAAATATCCCGTA
GAGGCTCTAACTACCATGATACGCATAGCCGAAAGGGTCGAACGCTCGCTTAACTGTGATGCTGCTTTTTATGATAAGGC
TATATCCTCAGCTAGCATTACAAACGCTATAAGCCATGCTACATGTACTATAGCACGGGACCTAGGTGCCAGAGCCATAA
TAACCGCTACAAAGTCAGGCTATACTGCAAGAATGGTGGCCAAATACAGGCCGGTGGCTCCGATAATAGCGACCACTATA
AGCGAAATGGTGTACAATAAATTATCGTTGGTATGGGGCGTAGTGCCGTTTTTGGCCTCTCAGATGGAAGGTACAGACGA
AATGATAGAACAATCAGTCGATATCGCTTTGGAATCTGAACTGATAAGCAGCGGAGATCTGGTCGTTATCACGGCAGGTG
TTCCAGTAGGAGTAAGTGGCACTACCAATCTTATAAAGGTCCATATAGCTGGAGATATACTTGTCAAGGGCGTGGGATTC
GGTGTTAAAGCTGTATATGGCAGAGTATGCTCTATAAAAAACTATATGGATGCAAAGACCAAATTCAAGGATGGCGATAT
ATTAGTGGCTAAGTCTACCGACAATACGTTATTGCCATTCATGCGCAGAGCCTCGGCAATTATAACCGAAGAGGGCGGCA
TAGCCTCACATGCCGCTGTAGTTGGACTGACACTAGAGATACCAGTTATAGTGGGAGCCCAAGAAGCTACCGAAACATTG
ACTGATGGGATATGGGTAACAGTAGATCCACAACATGGCTTTGTGTATAACGGAAAGGCTGCTGTAATATAA

Protein sequence :
MRKTKIICTIGPASDDKAIFERLIAHGTNAIRLNFSHGSYEEHGKRIDMAKDARRSHNIPLSIILDTKGPEMRLGKFKIE
PVELREGQSFTLATRDIEGDNSIVSVNYAGLTKDIKQGDKLLLDDGLIELRVKDIEGTDIHCTVMNSGLISSKKSVNAPG
ISIQLPSVTQKDIDDIKFGVEKGIDTIAASFIRRAEDVLEIKRILEDNNAYDVQIIAKIENQEGINNLDDIMAVADGIMI
ARGDLGVEIPTEDVPVVQKAIISKCRDAGKPVIIATQMLDSMIRNPRPTRAEATDVANAIYEGADAIMLSGETASGKYPV
EALTTMIRIAERVERSLNCDAAFYDKAISSASITNAISHATCTIARDLGARAIITATKSGYTARMVAKYRPVAPIIATTI
SEMVYNKLSLVWGVVPFLASQMEGTDEMIEQSVDIALESELISSGDLVVITAGVPVGVSGTTNLIKVHIAGDILVKGVGF
GVKAVYGRVCSIKNYMDAKTKFKDGDILVAKSTDNTLLPFMRRASAIITEEGGIASHAAVVGLTLEIPVIVGAQEATETL
TDGIWVTVDPQHGFVYNGKAAVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-90 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-90 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-89 48
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-89 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mahau_1398 YP_004463413.1 pyruvate kinase VFG0479 Protein 3e-90 48