Gene Information

Name : TepRe1_0862 (TepRe1_0862)
Accession : YP_004460344.1
Strain : Tepidanaerobacter acetatoxydans Re1
Genome accession: NC_015519
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 933399 - 934598 bp
Length : 1200 bp
Strand : +
Note : TIGRFAM: Methionine gamma-lyase; KEGG: toc:Toce_1559 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

DNA sequence :
ATGGACGGTAAAGTGAAAGGTTTTAATACAAAAGCTATTCATGCGGGACAAAAGCCCTGTCCTGTTACCGGAGCACATGT
AACTCCGATTTATCAAACTTCTACCTTTGTGTTTAAGGATGTGGACCAAGGTGCACGCAGGTTTGCAGGCGAGGAGGAGG
GCTATATCTACACAAGGCTCGGCAACCCTACTTTAACCGAGCTTGAGGCAAAAGTCGCCGCATTGGAAGGCGGAGAAGCA
GCTATCGGCGCAGCTTCCGGCATGGCTGCAATCTCCACCGCACTTGTAACGCTTTTGAAGAAAGGCGATCATATTGTAGC
AGGTGATGCCCTCTATGGATGTACCCACAGTTTTATAAGCGAGATTTTACCGCAATACGGTATTGAGGTAACCATGGTGG
ATACATCTAATTTGGAAAACATCGAAAACGCAATGAAACCTAACACTAAAGTAATTTATGTAGAAACTCCGGCAAATCCC
ACAATGAAGCTTGTAGATTTGGAAGGTGCCTCCGACATAGCTCATAAACACGGTGCAATTATTATAGTTGACAACACATT
TATGTCGCCTTATCTGCAGCGCCCCATCGAACACGGTGTTGACGTAGTTGTTCACAGTGCCACAAAATATATAGGCGGGC
ATGGCGATGTGCTTGCAGGCCTGATAATCGGGCCCAAGGAACTGATAGATACTATGCGCATACCTTATTTAAAGGATTTT
GGCGGAATTTTATCGCCTTTTGATGCATGGCTTTTACTGAGAGGACTTAAAACTCTAGGAGTTAGAATGGATCGGCACTG
TGCCAATGCACAAAAGGTAGCGGAATACTTGGAAAAACATCCGTTGATTGATAAAGTTTACTATCCGGGCCTTCCATCAC
ATCCGCAGTATGAACTGGCAAAGAAACAAATGGACGGTTTTGGCGGCATGATGAGCTTCGAGCTGAAAGGCGGTCTTGAA
GCAGGTAAAGTATTGATGAATAGCGTAAAAATGATAACACTTGCCGTAAGTCTGGGTTGTGTTGATTCGCTTATCCAGCA
TCCGGCTTCTATGACACATTCGCCGGTGCCGCGTGAGGAAAGGCTGAAGGCAGGCATTACCGATGGGCAGGTAAGACTTT
CGGTCGGCATCGAAGATGTGGAAGATATTATCGCAGACTTGGATCAGGCTTTAAAAGAAGTTGAAAAACAAACAATGTAA

Protein sequence :
MDGKVKGFNTKAIHAGQKPCPVTGAHVTPIYQTSTFVFKDVDQGARRFAGEEEGYIYTRLGNPTLTELEAKVAALEGGEA
AIGAASGMAAISTALVTLLKKGDHIVAGDALYGCTHSFISEILPQYGIEVTMVDTSNLENIENAMKPNTKVIYVETPANP
TMKLVDLEGASDIAHKHGAIIIVDNTFMSPYLQRPIEHGVDVVVHSATKYIGGHGDVLAGLIIGPKELIDTMRIPYLKDF
GGILSPFDAWLLLRGLKTLGVRMDRHCANAQKVAEYLEKHPLIDKVYYPGLPSHPQYELAKKQMDGFGGMMSFELKGGLE
AGKVLMNSVKMITLAVSLGCVDSLIQHPASMTHSPVPREERLKAGITDGQVRLSVGIEDVEDIIADLDQALKEVEKQTM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-62 44
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-67 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-68 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TepRe1_0862 YP_004460344.1 methionine gamma-lyase BAC0207 Protein 2e-94 54