Gene Information

Name : TepRe1_1786 (TepRe1_1786)
Accession : YP_004461224.1
Strain : Tepidanaerobacter acetatoxydans Re1
Genome accession: NC_015519
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1842207 - 1844798 bp
Length : 2592 bp
Strand : +
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: tjr:TherJR_0928 ATP-dependent chaperone ClpB; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGGTGACAGCCTTGGATCTTAATAAATATACTCAAAAATCTCAAGAAGCCATTTTAAATGCTCAAAATCTTGCATTAGA
GCATCATCATCAAGAAATGACTTCAAAGCATTTATTTTACGCTCTTGTATTTCAGAAGGACGGTATTGTACCGCTGATTA
TAGAAAGGGCGGGAGTCAATGTCAATCAAATTAAATCATTGGCCGAAGACCTGTTAAAACGTATACCTTCTGTTCACGGT
TATGATGGGCCATTGTCCATGAATGCAAATCTTGCCAGGGTTTTTATCAGAGCAGAGCGCGAAGCTCAGAACATGAAGGA
TGAATTTGTAAGTGTCGAACACCTGCTTCTGGCATTGTTGGAAGAGGGCGACACAGATGTAAGGGATGCCTTGAAAAAGG
CAGGTCTGGATAGGGTAGCCATACTGACAGGCCTAAAACAAGTTCGCGGCAGTCAGCAGGTTAACAGTGAAAATCCCGAA
GCTACTTATAATGCTCTTGAAAGATACGGCCGAGACCTTACCCGCTTGGCTCGCGACGGCAAACTTGACCCGGTTATCGG
TAGAGATGATGAGATAAGGCGGGTCATCGAAATTCTGTCAAGGCGAACAAAAAACAACCCTGTTCTCATAGGTGAAGCCG
GTGTGGGAAAAACTGCCATAGTAGAAGGTCTTGCCCGACGCATCGTGGCAGGGGATGTTCCGGAAGGTTTAAAGAATAAA
CAGATAATTGCTTTAGATATGGGTTCCCTTATAGCAGGTGCAAAATTTAGAGGAGAATTTGAAGAAAGGCTTAAGGCAGT
TCTAAAGGAAGTGCAGGAGTCCGACGGTCAAATCATACTCTTTATCGATGAGCTTCATACCGTAGTAGGTGCAGGTGCTG
CCGAAGGGGCCTTGGATGCAGGGAATATCTTAAAACCCTTGTTGGCACGTGGAGAGCTAAGAGTTATCGGTGCCACCACT
ATTGATGAGTACCGCAAATACATCGAAAAAGATGCTGCTCTTGAACGCCGTTTCCAACCGGTGATGGTCAATCCCCCATC
GGTGGAAGATACTATTTCCATCTTAAGAGGTCTTAAAGAAAGATATGAGGTGTTCCACGGTGTCCGAATAAAGGATAATG
CCATAGTAGCATCCGCAACACTTTCAGATAGATATATTACCGATCGTTTCCTGCCGGATAAGGCTATCGACTTAATGGAT
GAAGCTGCGGCTCGACTTCGCACTGAAATTGACAGTATGCCAGTTGAGCTTGATGAAATAAAACGTAAAATAATTCAGCT
TCAGATTGAGGAAACTGCGTTGAAGAAGGAAAAGGACGAAGCATCACTTAAGAGGCTTGAAAAGATACAGGAGGAAATGA
GTAAACTTCAAGATGAATTTGACAGGCTAAATGTCTTGTGGCAGCAAGAAAAAGAAGAAATAAGCAGGATTCATAAAATA
AAATCCGAAATCGAAAAGGTAAAGCTTGAAATTGAAAAGGCAGAACGTGAATATGACCTTAATAAAGTTGCAGAACTTAA
GTTCGGAAGGCTGAATGAACTTGAAAGACAGTTAAAAGCTGAAGAGGAGGCCATCCGGCAAAGACAGAAAGAAGGCGGAC
TTTTAAAGGAAGAGGTCGACGAAGAAGAAATTGCAAGGGTGGTCAGTCAGTGGACAGGTGTTCCCATTGATAAGCTCCTT
GAAGGTGAAAAAGAAAAGCTGCTTAACCTAGAAGATATCCTGCACCGCCGGGTGGTCGGTCAGGATGAAGCGGTTAAGGC
CGTTGCAGATGCCATACTGCGTGCAAGAGCCGGTATCAAAGACCCGTCAAGACCTATAGGAAGCTTTATATTCCTCGGTC
CCACCGGTGTTGGCAAGACTGAACTGGCTAAGGCTTTGGCTGAGGCATTGTTTGACGATGAGAGAAATATTATCCGGATA
GATATGTCCGAATACATGGAGAAACATGCGGTTTCAAGGCTTATAGGAGCGCCTCCGGGATATGTGGGCTATGAAGAAGG
CGGGCAGCTCACTGAAGCTGTGCGCACACACCCTTATTCCGTAATACTCTTTGATGAAATTGAAAAGGCTCATAATGACG
TGTTTAATGTGCTTCTCCAGATATTAGATGACGGTCGGCTTACCGACGGCAAGGGCCGCACCATAAACTTTAAAAACACC
GTATTGATTATGACATCGAATATTGGAAGTCAGGAAATCCTTGAATACCAATCTTCGAGAGATAAAAACTTTTCGCAAAT
TAAAGAGAAGGTTTTGAATTTATTAAAACACTACTTTAAACCGGAGTTTTTAAACCGTGTTGATGAGATAATAGTATTCC
ATCCCTTAGAGCCTGAGCATGTGGCAAAAATTGCCGAGCTGCTTTTGAATAATTTTGCTCAAAGGGTAAAGAATACTGCA
GGAATTAATTTGACATGGTCGGAAAAATCCGTAAGGTATTTAGCTGAAAAGGGCTATGATCCGCTGTTTGGAGCCCGGCC
GTTGAAGAGATTGATACAGCAAGAAATAGAAACACCTCTAAGCCGGAAAATTATTGAAGGAGTAAGGCCCGGAGAAGTGA
TCAACATCGATGAAATCTTAAAAGTTGATTGA

Protein sequence :
MVTALDLNKYTQKSQEAILNAQNLALEHHHQEMTSKHLFYALVFQKDGIVPLIIERAGVNVNQIKSLAEDLLKRIPSVHG
YDGPLSMNANLARVFIRAEREAQNMKDEFVSVEHLLLALLEEGDTDVRDALKKAGLDRVAILTGLKQVRGSQQVNSENPE
ATYNALERYGRDLTRLARDGKLDPVIGRDDEIRRVIEILSRRTKNNPVLIGEAGVGKTAIVEGLARRIVAGDVPEGLKNK
QIIALDMGSLIAGAKFRGEFEERLKAVLKEVQESDGQIILFIDELHTVVGAGAAEGALDAGNILKPLLARGELRVIGATT
IDEYRKYIEKDAALERRFQPVMVNPPSVEDTISILRGLKERYEVFHGVRIKDNAIVASATLSDRYITDRFLPDKAIDLMD
EAAARLRTEIDSMPVELDEIKRKIIQLQIEETALKKEKDEASLKRLEKIQEEMSKLQDEFDRLNVLWQQEKEEISRIHKI
KSEIEKVKLEIEKAEREYDLNKVAELKFGRLNELERQLKAEEEAIRQRQKEGGLLKEEVDEEEIARVVSQWTGVPIDKLL
EGEKEKLLNLEDILHRRVVGQDEAVKAVADAILRARAGIKDPSRPIGSFIFLGPTGVGKTELAKALAEALFDDERNIIRI
DMSEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRTHPYSVILFDEIEKAHNDVFNVLLQILDDGRLTDGKGRTINFKNT
VLIMTSNIGSQEILEYQSSRDKNFSQIKEKVLNLLKHYFKPEFLNRVDEIIVFHPLEPEHVAKIAELLLNNFAQRVKNTA
GINLTWSEKSVRYLAEKGYDPLFGARPLKRLIQQEIETPLSRKIIEGVRPGEVINIDEILKVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-158 45
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 8e-100 44
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 6e-100 44
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-97 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TepRe1_1786 YP_004461224.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-110 43