Gene Information

Name : MPTP_0527 (MPTP_0527)
Accession : YP_004455811.1
Strain : Melissococcus plutonius ATCC 35311
Genome accession: NC_015516
Putative virulence/resistance : Virulence
Product : UDP-N-acetylglucosamine 4,6-dehydratase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : 4.2.1.-
Position : 558885 - 560462 bp
Length : 1578 bp
Strand : +
Note : GO:0009058

DNA sequence :
ATGACTGCTGCTTCAATTTGTGAATTTTTTTTACTTTTGTTATTAGATTTAAACGATGATTATCGTTTTGTACTACTCAC
CTATTTAGTAGCTAATTTTTTAATTATAACTAGTCGTTTAGTATGGTGTACGATCATAGAAGCTAAAAGTAAAAGCAAAG
TACATGGTAATCAAGTATATCCTAAACAAACATTGATTATAGGTGCAGGTGAAGCTGGACAACTTTTATTAAATAGTTTA
CATACTTCTGCAAAAAATAGTGGAATTAAGGTGATTGGGTTAATTGATGATGCGCCTGATAAATACCATACTTACTTATC
AGGAGTTAGAGTATTAGGAAATACAAAACAAATTCCAAATATTATAAAAGATTATGATATTGAAATGTTAACTTTAGCAA
TACCTTCTATTCATCCTGAGCAATTAAAAAGAATTTTAGATATCATTACACCGCTTGGCTTGCCTGTCAATTCGATGCCA
GATTTAGAGGAAGTTGCCTCTGGAAATATTACAATTTCTAGATTAAAAGAAATAGATGTTATAGATCTTTTAGGACGAGA
AGAGGTTCAATTAAATATTGAGCAAATCAAAGATCAATTATCGAATAAAGTTATTTTAGTTACAGGTGCCGGTGGTTCCA
TTGGTTCTGAGATTTGCCGTCAAGTGATGAATTTTAATCCAAAAACATTGATTTTATTAGGACATGGTGAAAATTCTATT
TATCTTATTGAAAAAGAACTACATAATACTTTCCAGCATACTTCAACTGAAATTATTCCAATAATTGCTGATATTCAGGA
CAAGCAACAAATGGTAGAAATTATGAAAAGATTTCATCCACAAATTGTTTATCATGCAGCCGCTCATAAACATGTTCCTT
TAATGGAATACAATCCACAATCTGCTATTAAAAATAATATATTTGGTACAAAAAATACTGCTGAGGCTGCAAAAGCAGCA
AATGTTGCTAATTTTGTTATGATTTCAACGGATAAAGCAGTAAATCCACCTAATATTATGGGAGCGACAAAACGAGTTGC
TGAATTAATCATTACAAACTTAAATAAGACAGGGAATACAAAATTCTGTGCCGTTCGTTTTGGAAATGTACTTGGAAGTC
GGGGAAGTGTCATTCCCTTATTTAAAGAACAAATCAACAAAGGTGGTCCAATTACCATTACTGATTTTCGAATGACACGT
TATTTTATGACTATTCCTGAAGCGAGTCGTTTAGTGATTCAGGCAGGTGCCTTGGCTAGAGGGGGAGAAATTTTTATTTT
GGATATGGGTGATCCTGTGAAAATTATTGACCTAGCTAAAAATATGATTAAATTAAGCGGTTATAAAGAAAACGAAATTA
AAATTATCGAAACAGGAAGTCGACCTGGCGAAAAATTATATGAGGAATTATTGGTAAATAAAAAGAAAAATCATAAACAG
GTATTTGATAAGATTTTTATTGAAGATATTAGAGGTTCCTTTCCAGATGAGGTTTTACCATTTGTTGACAATTTATCAAT
GGCCTCTAAATCTCTTGCAGAAGACATCATTCGTTTTGCCAATGCCTCAAGTCATTAG

Protein sequence :
MTAASICEFFLLLLLDLNDDYRFVLLTYLVANFLIITSRLVWCTIIEAKSKSKVHGNQVYPKQTLIIGAGEAGQLLLNSL
HTSAKNSGIKVIGLIDDAPDKYHTYLSGVRVLGNTKQIPNIIKDYDIEMLTLAIPSIHPEQLKRILDIITPLGLPVNSMP
DLEEVASGNITISRLKEIDVIDLLGREEVQLNIEQIKDQLSNKVILVTGAGGSIGSEICRQVMNFNPKTLILLGHGENSI
YLIEKELHNTFQHTSTEIIPIIADIQDKQQMVEIMKRFHPQIVYHAAAHKHVPLMEYNPQSAIKNNIFGTKNTAEAAKAA
NVANFVMISTDKAVNPPNIMGATKRVAELIITNLNKTGNTKFCAVRFGNVLGSRGSVIPLFKEQINKGGPITITDFRMTR
YFMTIPEASRLVIQAGALARGGEIFILDMGDPVKIIDLAKNMIKLSGYKENEIKIIETGSRPGEKLYEELLVNKKKNHKQ
VFDKIFIEDIRGSFPDEVLPFVDNLSMASKSLAEDIIRFANASSH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 5e-107 52
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 4e-104 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MPTP_0527 YP_004455811.1 UDP-N-acetylglucosamine 4,6-dehydratase VFG1300 Protein 7e-109 55
MPTP_0527 YP_004455811.1 UDP-N-acetylglucosamine 4,6-dehydratase VFG0029 Protein 2e-74 41